The anomalous x-ray pulsar 4U 0142+61: a neutron star with a gaseous fallback disk

The recent detection of the anomalous X-ray pulsar (AXP) 4U 0142+61 in the mid infrared with the Spitzer Observatory (Wang, Chakrabarty & Kaplan 2006) constitutes the first instance for a disk around an AXP. We show, by analyzing earlier optical and near IR data together with the recent data, that the overall broad band data can be reproduced by a single irradiated and viscously heated disk model

A natural limit on the observable periods of anomalous x-ray pulsars and soft gamma-ray repeaters

We investigate the dependence of the evolution of neutron stars with fallback disks on the strength of the magnetic dipole field of the star. Using the same model as employed by Ertan et al. (2009), we obtain model curves for different dipole fields showing that the neutron stars with magnetic dipole fields greater than ∼ 1013 G on the surface of the star are not likely to become anomalous X‐ray pulsars (AXPs) and soft gamma‐ray repeaters (SGRs). Other sources with conventional dipole fields evolve into the AXP phase if their disk can penetrate the light cylinder. The upper limits to the observed periods of AXP and SGRs could be understood if the disk becomes inactive below a low temperature around 100 K. We summarize our present and earlier results indicated by the evolutionary model curves of these sources with an emphasis on the importance of the minimum disk temperature and the X‐ray irradiation in the long‐term evolution of AXPs and SGRs with fallback disks

On fallback disks and magnetars

The discovery of a disk around the anomalous X-ray pulsar 4U 0142+61, has rekindled the interest in fallback disks around magnetars. We briefly review the assumptions of fallback disk models and magnetar models. Earlier data in optical and near IR bands combined with new Spitzer data in the mid-IR range are compatible with a gas disk. Higher multipole fields with magnetar strengths together with a dipole field of 1012-1013 G on the neutron star surface are compatible with the presence of a disk around the neutron star. The possible presence and properties of a fallback disk after the supernova explosion is a likely initial condition to complement the initial rotation period and initial dipole field in determining the evolutionary paths and different types of isolated neutron stars

Computational analysis of complicated metamaterial structures using MLFMA and nested preconditioners

We consider accurate solution of scattering problems involving complicated metamaterial (MM) structures consisting of thin wires and split-ring resonators. The scattering problems are formulated by the electric-field integral equation (EFIE) discretized with the Rao-Wilton- Glisson basis functions defined on planar triangles. The resulting dense matrix equations are solved iteratively, where the matrix-vector multiplications that are required by the iterative solvers are accelerated with the multilevel fast multipole algorithm (MLFMA). Since EFIE usually produces matrix equations that are ill-conditioned and difficult to solve iteratively, we employ nested preconditioners to achieve rapid convergence of the iterative solutions. To further accelerate the simulations, we parallelize our algorithm and perform the solutions on a cluster of personal computers. This way, we are able to solve problems of MMs involving thousands of unit cells

Determination of macro and trace element levels of serum, tears, saliva, and hair samples in kilis goats with icp-ms

This study is focused on the evaluation of macro and trace elements concentration including sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), iron (Fe), copper (Cu), zinc (Zn), selenium (Se), nickel (Ni), titanium (Ti), manganese (Mn), cobalt (Co), and chromium (Cr) of the serum, saliva, tears, and hair samples in Kilis goats. The study involved 33 goats without clinical signs of disease. Individual serum, saliva, tears, and hair samples from each goat were collected for element quantifications through the inductively coupled plasma mass spectrometry (ICP-MS) method after acid digestion in a microwave system. Element concentrations varied and depended on the sample type. The most predominant element in serum and saliva samples was Na (3559±55.2 and 3265±53.6 mg/L, respectively), followed by K>Ca>Mg. Potassium was the most abundant element analyzed in tears and hair samples (3506±305 and 4664±100.5 mg/L, respectively). The major trace element was Fe in all sample types except hair samples. Nickel was detected only in serum samples (83.9±6.35 μg/L) and Mn was detected only in hair samples (12903±3142 μg/L). In all samples, Co was below the detection limit. There was a significant correlation of some elements between serum and hair (Na, K, Mg, Cu), tears and hair (K, Mg, Fe), serum and tears (K) samples. Trace elements concentration did not pose a risk for deficiency or excess. It was concluded that tears and saliva are potential alternative materials for element analysis and simultaneous tears, saliva, and hair along with serum could be useful in predicting the inorganic metabolic status of goats

A Rare Complication of Chronic Otitis Media: Cerebellar Abscess

Chronic otitis media (COM) and its associated complications are currently less common because of the popularity of imaging modalities such as computed tomography and magnetic resonance imaging and the increased use of antibiotics. Patients can be treated without any complications owing to early diagnosis. Despite all these new developments and opportunities, complications of autogenous cerebellar abscess may develop and be fatal. In this case report, we present our own clinical experience regarding a patient with cerebellar abscess as a complication of COM

The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study

IntroductionElevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker muscular dystrophy (DMD/BMD) in male children and Pompe disease (PD) in male and female children with isolated hypertransaminasemia.MethodsThis multi-center, prospective study enrolled patients aged 3–216 months with serum alanine transaminase (ALT) and/or aspartate transaminase (AST) levels >2× the upper limit of normal (ULN) for ≥3 months. Patients with a known history of liver or muscle disease or physical examination findings suggestive of liver disease were excluded. Patients were screened for creatinine phosphokinase (CPK) levels, and molecular genetic tests for DMD/BMD in male patients and enzyme analysis for PD in male and female patients with elevated CPK levels were performed. Genetic analyses confirmed PD. Demographic, clinical, and laboratory characteristics of the patients were analyzed.ResultsOverall, 589 patients [66.8% male, mean age of 63.4 months (standard deviation: 60.5)] were included. In total, 251 patients (188 male and 63 female) had CPK levels above the ULN. Of the patients assessed, 47% (85/182) of male patients were diagnosed with DMD/BMD and 1% (3/228) of male and female patients were diagnosed with PD. The median ALT, AST, and CPK levels were statistically significantly higher, and the questioned neurological symptoms and previously unnoticed examination findings were more common in DMD/BMD patients than those without DMD/BMD or PD (p < 0.001).DiscussionQuestioning neurological symptoms, conducting a complete physical examination, and testing for CPK levels in patients with isolated hypertransaminasemia will prevent costly and time-consuming investigations for liver diseases and will lead to the diagnosis of occult neuromuscular diseases. Trial RegistrationClinicaltrials.gov NCT04120168

Atların Ön Bacak Fleksor Tendolarında Akut Peritendinitislerin Termografik, Ultrasonografik ve Radyografik Tanısı

Bu çalısmada çesitli ırklara ait beygir ve kısrakların agır egzersiz öncesi ve sonrası peritendo’da meydana gelen akut yangının termografik, ultrasonografik ve radyografik yöntemlerle karsılastırmalı erken tanısı ve devam eden iyilesme sürecindeki degerler incelenmistir. Ön ekstremitelerin, fleksor tendolarından musculus flexor digitorum superficialis (MFDS) ve musculus flexor digitorum profundus (MFDP) tendolarının muayene ve ölçüm degerleri kayıt edilip 14 gün süreyle takip edilmistir. Termografi cihazıyla agır egzersiz öncesi, egzersizden 20 dk, 35 dk, 50 dk, 80 dk, 7. gün ve 14. gün sonraki görüntüleri alındı. Vücuttan yayılan infrared (kızılaltı) ısının degerleri ölçülerek farklı sürelerdeki ısı ortalamaları arasında istatistiksel olarak anlamlılık olup olmadıgı varyans analizi (ANOVA) ve Duncan Testi ile irdelenmistir. statistiksel degerlendirmelerde termografi ölçümlerinde egzersiz öncesi ve egzersiz sonrasında incelenen her bölgedeki sıcaklık ortalamaları arasında anlamlı farklar gözlenmistir (p<0,05). Ayrıca yapılan Ki-kare bagımsızlık testi sonucunda, egzersiz öncesinde sol bacak 1. bölgedeki sıcaklık ile yas arasında ve egzersiz sonrası 20. dk daki sol bacak 1. bölgedeki sıcaklık ile cinsiyet arasında bagımlılık oldugu tespit edilmistir (p<0,05). Ultrasonografik muayene ve ölçümlerde egzersiz öncesi ve termografiyi takiben egzersiz sonrası 90 dk, 7. gün ve 14. günlerde tendoların mesafe, kalınlık, çevre ve alan degerleri ölçülmüstür. Muayenede 8 MHz lineer prob ara yastıkla transversal olarak ve ara yastıksız longitudinal olarak kullanılmıstır. Ultrasonografi degerleri arasında istatistiksel olarak anlamlı bir fark olmadıgı gözlenmistir (p>0,05). Radyografik olarak röntgen çekimleriyle tendoların görüntüsü elde edilememistir. Elde edilen verilerde termografi cihazının üstün özelliklere sahip oldugu, küçük sıcaklık degisimlerini tespit etmede bile çok duyarlı oldugu belirlenmistir. Diger tanı yöntemlerine (ultrasonografi, radyografi, nükleer sintigrafi gibi) alternatif olmak yerine beraber kullanıldıgında tanıya yardımcı oldugu sonucuna varılmıstır.In this study, comparisons of early diagnosis and healing process of acute inflammation in peritendon by thermographic, ultrasonographic and radiographic techniques in various breeds of stallion and mares were investigated. Values of examination and measurement of front limb of flexor tendons m. flexor digitorum superficialis and m. flexor digitorum profundus were recorded and followed for 14 days. Before enduring egzersize, 20, 35, 50 and 80 mins after egzersize, 7th day and 14th day, images were recorded by an thermography device. The statistically significant differences between measured values of infrared rays from the body were evaluated by analysis of variance (ANOVA) and Duncan tests. There were statistically significant differences in thermographic values between before egzersize and after egzersize (p<0,05). Moreover, using Chi-square independence test, there was a statistically significant difference between heat in regio I and age of animal in left front limb and it was also observed that there was a correlation between heat and sex at 20 min after egzersize (p<0,05). In ultrasonographic examination and measurement before enduring egzersize and 1.5 hour after thermographic examination, at 7th and 14th days distance, length, border and area of tehnods were obtained. An 8 MHz linear probe was used transversally with an interface and longitudinally without interface. No statistically significant difference was observed in ultrasonographic values. (p>0,05). X-ray analysis showed no visible images of tendons. Data obtained here showed that thermography has superior features, and very sensitive to detect minute temperature changes. Not alone but used in combination with other diagnostic techniques (ultrasonography, radiography, scintigarphy etc) it will support the diagnosis

Over karsinomu takibinde tümör markerlerinden carcinoembriyojenik antijen ve ferritin değeri

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.Bu çalışmada 1986 - 1987 yılları arasında kliniğimizde yatarak takib ve tedavi edilen 20 over kanseri olgusuyla, 19 benign jinekolojik hastalıklı olguda radioimmunassay yöntem ile CEA ve Ferritin düzeyleri saptandı. İki grubun hemoglobin değerleri ile over kanseri grubunun karaciğer fonksiyon testleri saptandı. Over kanseri grubu klinik tümör saptanan ve saptanma yan olarak iki grubda incelendi. İki grub arasında CEA, Ferri tin, Hb ve karaciğer fonksiyon testleri bakımından istatistiksel olarak inceleme yapıldı. Over kanseri ve benign jinekolojik hastalıklı grub da elde edilen sonuçlar istatistiksel olarak incelendi. Sonuç olarak Ferritin' in sadece over kanserli olgularda arttığı ve duyarlı bir tümör m arken olduğu, CEA1 nin ise ilerlemiş over kanseri olgularında arttığı ve yanlış pozitifliğin fazla olması nedeniyle duyarlı bir tümör m arken olmadığı kanısına varıldı. Sonuç olarak CEA ve Ferritin'in over kanserinin takibinde yardımcı olabilecekleri fikrine varıld