46 research outputs found

    A Comparative Performance Analyze Model and Supplier Positioning in Performance Maps for Supplier Selection and Evaluation

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    AbstractIn supply chain, supplier has an important role and in this situation supplier evaluation and selection is gained more significance for companies. So that, it is purposed to improve an evaluation model to evaluate and select suppliers more effectively by correlate with company's supply chain. For that reason, a form is designing to collect data from concerned company's personnel and performance measuring model which includes scoring methodology and correlation analysis that is called as “Performance-Effect” analysis in this study. With this model, it is proposed to divest supplier evaluation from its general evaluation concept by presenting alternative selection criteria, suppliers and methods for working with positioning of these in performance maps

    PROLİFERE TRİKOLEMMAL TÜMÖR

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    Amaç: Prolifere trikolemmal tümör kıl folikülünün dış kök kılıfından gelişen, nadir görülen bir tümördür. Özellikle skalpte ve yaşlı bayanlarda gözlenir. Skuamöz hücreli kanser ile sık sık karıştığı için ayırıcı tanısı iyi yapılması gerekmektedir. Olgu sunumu: Olgumuzda gözün lateralinde iyileşmeyen yara ile başvuran hastaya yapılan medikal tedaviye rağmen fayda görmemesi üzerine kitle eksizyonu yapıldı ve patoloji sonucu pilar tümör olarak rapor edildi. Sonuç: Bu olguda bu tümörün tanı, kliniği ve histolojik özellikleri tartışılmıştı

    A Child with Acute Appendicitis Secondary to Blunt Abdominal Trauma: A Case Report and Review of the Literature

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    We present a child with abdominal pain and vomiting after blunt abdominal trauma (BAT). He had tenderness, guarding and rebound on the bilateral lower quadrant of the abdomen. He had no abrasion on the abdominal skin surface. He had marked leukocytosis and increased C-reactive protein level. Contrast-enhanced abdominal computed tomography revealed inflamed appendicitis. He was operated by pediatric surgeons and, an perforated appendix was illustrated on pathological examination. BAT and acute appendicitis (AA) are independently very frequent issues. In pediatric emergency departments, BAT and AA are very frequent issues, however, coexistence of these two condition in the same patient is rare. This case report and review of the literature showed that occurrence of AA after BAT should be considered by emergency physicians

    Comparison of Different Treatment Methods for Idiopathic Sudden Sensorineural Hearing Loss

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    Objective:To evaluate the effectiveness of different therapies for idiopathic sudden sensorineural hearing loss and prognostic factors, and determine the most successful treatment according to the audiogram type and time from onset to treatment.Methods:A total of 90 cases from February 2009 to January 2015 were classified under Group I oral treatment (methylprednisolone, acyclovir, betahistine-dihydrochloride, and vitamin B12); Group II oral treatment + intratympanic steroids (ITS); Group III oral treatment + hyperbaric oxygen; and Group IV only ITS. A pure tone average (PTA) improvement of less than 10 dB was assessed as “no improvement,” a PTA of 10 dB or more or a 10% or more increase in the speech discrimination score (SDS) as “partial improvement,” and a hearing threshold within 10 dB and SDS within 5%-10% of the unaffected ear as “full improvement.”Results:Overall, 32.2% patients showed full and 28.9% showed partial improvement, whereas 38.9% showed no improvement. There was no significant difference in terms of mean hearing gain between the different treatment methods. As the degree of hearing loss and time from onset to treatment increased, improvement worsened (p0.05).Conclusion:The most important factors affecting prognosis were the time from onset to treatment, hearing loss severity, and audiogram type. Only ITS avoided side effects and reduced hospitalization. ITS in the first two weeks, followed by hyperbaric oxygen were considered as the treatment priority

    Business against intimate partner violence; a case of participative action research and social action

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    This book is about the Business Against Domestic Violence (BADV) project, which has been initiated and coordinated by the Corporate Governance Forum of Turkey (CGFT) - a research center at Sabancı University’s School of Management, as a participatory action research project. The Project is aimed at exploring business agency in achieving gender equality through playing a catalytic role in mobilizing companies and business associations against IPV in Turkey in collaboration with the United Nations Population Fund (UNFPA) and the Turkish Industry and Business Association (TÜSİAD). Turkey represents an ideal setting for observing the role of business in achieving gender equality, as it has the highest gender gap amongst G-20 states following Saudi Arabia (WEF, 2018), the lowest labor force participation by women amongst all OECD countries (OECD, 2018), and a persistently high record of gender-based violence

    The efficacy of three regimes of uterotonic agents for prevention of postpartum blood loss at undergoing cesarean section: a prospective randomized clinical trial

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    Objectives: To compare the efficacy of three regimes of uterotonic agents on PPH in women undergoing cesarean section in our RCT. Material and methods: This study was a randomized controlled study (NCT05083910) performed at the Bezmialem Vakif University between July 2021 and January 2022. All women were randomly allocated into three groups: Group I (n = 52) — oxytocin only; Group II (n = 52) — the combination of oxytocin plus intrauterine misoprostol; Group III (n = 52) — carbetocin only. The primary outcome measures were: PPH to evaluate with the change between the concentrations of preoperative and postoperative hemoglobin, hematocrit and intraoperative blood loss. Results: The blood loss characteristics, including the change in hemoglobin and the change in hematocrit concentration, intraoperative blood loss, intraoperative additional hemostatic uterine sutures and the need for additional uterotonics, were lowest in group III, although all groups were comparable in terms of blood loss parameters. Group III had the highest blood loss ratio, exceeding 1000 mL. For the combination of oxytocin and intrauterine misoprostol, the ARR was 3.8% (95% CI 20.02–12.33), with a RR of 1.18 (95% CI 0.58–2.39) and a NNT of 26 (95% CI 8.1–4.9); for carbetocin, the ARR was 5.8% (95% CI 22.15–10.61), with a RR of 1.27 (95% CI 0.63–2.53) and a NNT of 17 (95% CI 9.41–4.51). Conclusions: Our results demonstrate that carbetocin shows no superiority in the prevention of PPH in women undergoing cesarean section. Oxytocin still seems to be a highly effective alternative to prevent PPH

    Evaluation of DNA damages in congenital hearing loss patients

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    In the current study, we aimed to compare the level of genetic damages measured as micronucleus (MN), nucleoplasmic bridge (NPB), and nuclear bud formation (NBUD) in congenital hearing loss patients (n = 17) and control group (n = 24). The cytokinesis-blocked micronucleus assay (CBMN) as applied to the blood samples to measure the frequency of the markers in both groups. The frequencies of MN of hearing loss patients were found to be consistently significantly higher than those obtained for the control group (p < 0.0001). Similarly, we found significantly higher frequency of NPB in patients was obtained for the patient group (p < 0.0001). Finally, the frequencies of NBUD in patients is significantly higher than the level measured in the control group (p < 0.0001). Furthermore, the age-adjusted MNL, BNMN, NPB, and NBUD frequencies in the patients were significantly higher than those obtained in the control group. We observed that the frequency of MN in patients was positivelycorrelated with NBUD frequency which may indicate a common mechanism for these biomarkers in the patientgroup. We found, for the first time, that there were statistically significant higher levels of MN, NPB, and NBUDin sensorineural hearing loss patients. Since the markers we evaluated were linked with crucial diseases, ourfindings might suggest that sensorineural hearing loss patients are susceptible to several crucial diseases, espe-cially cancer. Furthermore, the results demonstrated the significance of the MN, NPB, and NBUD level and thusprovides a potential marker for the diagnosis of congenital hearing loss patients

    Characterization of the BETA1 gene, which might play a role in Beta vulgaris subsp. Maritima salt tolerance

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    Salinity stress has a negative impact on plant growth, which affects homeostasis and productivity. The uptake of nonessential salt ions changes the osmotic balance of the cell and causes dehydration. Higher plants develop salt tolerance mechanisms to avoid dehydration. Sea beet (Beta vulgaris subsp. maritima) is a halophytic ancestor of cultivated sugar beet that displays salt stress tolerance. In this study, we screened a B. vulgaris subsp. maritima cDNA library in Saccharomyces cerevisiae strain Ab11c (ena1Δ, nha1/4Δ, nhx1Δ), which is deficient in sodium transport, to find sodium-detoxifying genes. We identified a cDNA construct, named BETA1, providing salt tolerance to yeast cells. This gene had no previously described function. Intracellular sodium measurements demonstrated no significant differences between yeast cells expressing BETA1 or a sham vector, suggesting that sodium was not effluxed in BETA1-expressing cells. Transcriptionally, BETA1 mRNA levels were induced immediately in leaves and later in the root system in response to the salt stress. Our results suggest that the BETA1 gene is part of the salt tolerance network in B. vulgaris subsp. maritima.Scientific and Technological Research Council of Turkey (115Z694
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