The relationships among impulsivity, anxiety sensitivity and nonsuicidal self-injury characteristics in patients with phobias

Background: The relationship between impulsivity and nonsuicidal self-injury (NSSI) has been revealed in several mental disorders other than phobias. Objectives: The purpose of this study was to examine the relationships among impulsivity, anxiety sensitivity, and NSSI characteristics in patients with phobias, and to compare these relationships with healthy controls. Methods: The sample of this study consisted of outpatients (n = 109) who had been diagnosed with social phobia, agoraphobia or simple phobia in addition to healthy individuals (n = 51) serving as the control group. Data collection tools were the socio-demographic form, the Barratt Impulsivity Scale (BIS-11), the Inventory of Statements About Self-Injury (ISAS), and the Anxiety Sensitivity Index (ASI-3). Results: Mean BIS-11 and ASI-3 scores in the social phobia and agoraphobia groups were found to be significantly higher than those in the control group. In addition, a positive correlation was found between ISAS and cognitive anxiety sensitivity scores in the agoraphobia and simple phobia groups. Discussion: The study revealed a positive correlation between cognitive anxiety sensitivity and NSSI in both the agoraphobia and simple phobia groups. The results of this study indicate that anxiety sensitivity may play a regulatory role between impulsivity and NSSI in some sub-groups of phobia

Effect of escitalopram treatment on white blood cells in patients with major depression

22nd Congress of the European-College-of-Neuropsychopharmacology -- SEP 12-16, 2009 -- Istanbul, TURKEYWOS: 000270312500558…European Coll Neuropsychopharmaco

Low-dose venlafaxine-associated liver toxicity in chronic hepatitis

WOS: 000188188100030PubMed: 14742779

The Relationship between personality disorders and post-traumatic stress disorder developed after earthquake

Giriş ve Amaç: Travma sonrası stres bozukluğu (TSSB) maruz kalınan travma ile ilişkilidir, ancak tek belirleyici travma değildir. Kişilik bozuklukları ile TSSB arasındaki ilişki tartışılmaktadır. Biz kişilik bozukluğu olanlarda TSSB’nin daha kolay geliştiğini ileri sürerek bu çalışmayı planladık. Gereç ve Yöntem: Çalışmamızı 17 Ağustos ve 12 Kasım 1999’da iki şiddetli deprem yaşayan Düzce’de yaptık. Travma birimine yönlendirilen 18 yaş üstü 109 hastadan klinisyen tarafından travma sonrası stres bozukluğu ölçeği (CAPS) ile TSSB tanısı konan 62 hasta çalışmaya alındı. Bunlara SCID-II, yaşam olaylarının etkisi ölçeği (IES) ve sosyodemografik bilgi formu uygulandı. Bulgular: Hastaların 35’inde (%56,5) kişiliği bozukluğu bulundu., kalan 27 hastada (%43,5) kişilik bozukluğu yoktu. 62 hastanın 54‘ü kadındı. Diğer sosyodemoğrafik değişkenler açısından iki grup arasında istatistiksel fark yoktu, sadece sosyal güvence oranı kişilik bozukluğu olmayanlarda daha yüksekti(MWU:312500, z:-2.303, p:0.021 ). Kişilik bozukluğu olan 35 hastada toplam 52 adet kişilik bozukluğu tanısı kondu. Bunların %84,7’sini kaçıngan, obsesif-kompulsif, bağımlı ve paranoid kişilik bozuklukları oluşturuyordu. Kişilik bozukluğu olan ve olmayan iki grup arasında CAPS alt ölçekleri ve IES alt ölçekleri puanları açısından istatistiksel anlamlı fark yoktu. Sonuç: Bulgularımız bize kişilik bozukluğunun TSSB şiddeti üzerinde belirleyici olmadığını, ancak TSSB’nin ortaya çıkışını belirleyen önemli bir faktör olduğunu düşündürmektedir.Introduction and Aim: Posttraumatic stress disorder (PTSD) is related to the trauma exposed, yet not the single predictive one. The relationship between personality disorders and PTSD has not been fully determined. We planned the present study claiming that personality disorders can facilitate the development of PTSD. Material and Method: We conducted the current study in Duzce where two severe earthquakes occurred on 17th August and 12th November 1999. One- hundred and nine patients above 18 years of age were referred to psychiatry trauma unit from the general psychiatry out-patient clinic. CAPS scale was administered to these patients and 62 patients diagnosed with PTSD were included in this study. We administered SCID-II, IES, and sociodemographic data form to these patients. Results: We found personality disorder in 35 patients (56.5%). No personality disorder was found in the remaining 27 patients (43.5%). There was no statistical difference between two groups with regar do other sociodemographic characteristics. Only social security rate was higher in patients who had not personality disorder (MWU: 312500, z:-2.303, p: 0.021). Fifty-two elements of personality disorders were diagnosed in 35 patients with personality disorders. 84.7% of these included avoidant, obsessive compulsive, dependant, and paranoid personality disorders. No statistically significant difference was found between the groups with or without personality disorder with regard to CAPS subscales and IES subscales scores. Conclusion: Our findings suggest that personality disorder has not a predictive role on PTSD but it is an important factor in the development of this disorder

Paroxetine induced reversible dyskinesia: a case report

WOS: 000408012700015Selective serotonin reuptake inhibitors (SSRI) are the primary medications that have been used recently for the treatment of psychiatric disorders. Paroxetine is one of the medications in the category of SSRI. In the literature, dyskinesia cases related to paroxetine are quite rare in comparison to other movement disorders, and the ones that have been presented are facial dyskinesia. The purpose of this report is to present an involuntary choreiform dyskinesia case that appears in the extremities related to addition of paroxetine on chlorpromazine. To our knowledge, our case, extremity dyskinesia related to paroxetine is the first case that has been observed so far

Comparison of child bringing-up attitudes of families having mentally retarded children and families who have healthy children

Amaç: Sağlıklı aileler, “fonksiyonel aile” olarak tanımlanıp, çocuğun psiko-sosyal gelişimini sağlıklı bir şekilde sürdürmesini sağlar. Ailede hasta veya özürlü bir kimsenin olması, aile işlevselliğini bozar. Çalışmamızda hipotez olarak özürlü çocuğa sahip ailelerin aile işlevselliğinin bozuk olacağını öne sürdük. Bu amaçla, özürlü çocuk ailesi ile sağlıklı çocuk ailesinin işlevselliği karşılaştırıldı. Yöntem: İlköğretim özel alt sınıfında ve özel rehabilitasyon merkezlerinde eğitim gören zihinsel engelli 50 çocuğun ailesi ile, normal eğitim gören 30 sağlıklı çocuğun ailesine demografik özellikleri içeren bir anket formu ve “Aile Değerlendirme Ölçeği” uygulandı. Sonuçlar istatistiksel analizle değerlendirildi. Bulgular: Özürlü çocuğu olan ebeveynlerin %24’ünün suçluluk ve pişmanlık duyduğu, %14’ünün isyan ve yılgınlık yaşadığı, %20’sinin çaresizlik ile yeterli sabır ve anlayışı gösteremedikleri gösterildi. Özürlü çocukların psikolojik yardım alıyor olması (p0.05), babanın çalışmıyor alması(p0.01) ve annenin çalışıyor olması (p0.01) “davranış kontrolü” alt boyutlarını anlamlı düzeyde etkilemektedir. Annenin çalışıyor olması “gerekli ilgi gösterme” alt boyutunu da olumsuz yönde etkilemektedir(p0.05). Sonuç: Özürlü bir çocuğa sahip olmak, aile işlevselliğini belirgin olarak bozmaktadır. İşleyişin tekrar normal sınırlara çekilebilmesi için sosyal destek sistemlerinin çok iyi işleyerek gerektiğinde devreye girmesi gerekir.Purpose: A healthy family, which is decribed as &#8220;functional family&#8221;, provides a healthy psycho-social environment for the child development. Presence of a chronically ill or a mentally retarded member may distort family functioning. In our study we hypothesed that the family functioning of parents having a retarded child would be impaired. We compared the parents who has a retarded child and parents who has healthy children according to their family functioning. Methods: The participants were the parents of 50 mentally retarded children (being educated in special subclasses of primary schools and in private rehabilitation centers) and 30 healthy children (being educated in normal classes of primary schools). The parents were asked to complete a socio-demographic form (prepared by the authors) and &#8220;Family Assessment Device&#8221;. The data were analysed statistically. Results: It is showed that among the parents who have a retarded child, 24 % feel guilt and remorse, 14 % lived rebellion and exhaustion, 20 % could not exhibit adequate patience and understanding. For mentally retarded children, having psychological help (p<0.05), non-working father (p<0.01), and working mother (p<0.05) affected the &#8220;behavioral control&#8221; subdimension significantly. Working mother negatively affected the &#8220;exhibiting adequate attention&#8221; subdimension, as well. Conclusion: Presence of a retarded child considerably distorts family functioning. Social supports systems should perform flawlessly in order to make family functioning better

The assessment of MMPI in panic somatisation disorders: A comparative study

Aim: We aimed to investigate the relationship between anxiety disorders and somatisation disorders described in ICD-10 within the title of neurotic disorders, and the personality characteristics related to both groups Method: Fifty-eight individuals who were either have DSM-IV panic disorder (PD) and or somatisation disorder (SD) completed the Minnesota Multiple Personality Inventory (MMPI). Intergroup differences of MMPI scores and personality disorders were analyzed. Result: The scores obtained from the clinical subscales of PD (n:28) and SD patients (n:30), and in the MMPI test were similar in comparison. The differences between the MMPI scores of PD and SD patients were statistically significant regarding the passive-aggressive personality disorder, avoidant personality disorder, borderline personality disorder and obsessive-compulsive personality disorder scores. The mean values of the study conducted in a Turkish population sample were used as cut-points, the results were greater than normal in the psychastenia and depression subtest scores in group PD, and in deny subtest in group SD (p<0.01). Conclusion: The findings were compatible with those in the literature. All of these personality disorders above-mentioned and found high in PD with an exception of the borderline personality disorder share high comorbidity with neuroticism. However, comparative studies following treatment are required whether these characteristics are related to the personality structure or the nature of PD

The Assessment Of Mmpi In Panic And Somatisation Disorders: A Comparative Study

Aim : We aimed to investigate the relationship between anxiety disorders and somatisation disorders described in ICD-10 within the title of neurotic disorders, and the personality characteristics related to both groups. Method : Fifty-eight individuals who were either have DSM-IV panic disorder (PD) and or somatisation disorder (SD) completed the Minnesota Multiple Personality Inventory (MMPI). Intergroup differences of MMPI scores and personality disorders were analyzed. Result : The scores obtained from the clinical subscales of PD (n:28) and SD patients (n:30), and in the MMPI test were similar in comparison. The differences between the MMPI scores of PD and SD patients were statistically significant regarding the passive-aggressive personality disorder, avoidant personality disorder, borderline personality disorder and obsessive-compulsive personality disorder scores. The mean values of the study conducted in a Turkish population sample were used as cut-points, the results were greater than normal in the psychastenia and depression subtest scores in group PD, and in deny subtest in group SD (p< 0.01). Conclusion : The findings were compatible with those in the literature. All of these personality disorders above-mentioned and found high in PD with an exception of the borderline personality disorder share high comorbidity with neuroticism. However, comparative studies following treatment are required whether these characteristics are related to the personality structure or the nature of PD

Evaluation of dexamethasone suppression test in fibromyalgia patients with or without depression

WOS: 000183769800004PubMed: 12811674Objective: While in most healthy persons dexamethasone administration suppresses cortisol synthesis from the adrenal cortex, such suppression is not usually observed in patients with depression. We set out to investigate whether the dexamethasone suppression test (DST) reveals any neurobiological relationship between fibromyalgia (FM) and depression related to the hypothalamic-pituitary-adrenal (HPA) axis. Method. To discover a relationship between depression and FM we performed the DST in 2 0 FM patients with depression, 26 FM patients without depression and 20 healthy subjects serving as a control group. Results: Compared with the control group the cortisol level was found to be significantly higher in response to the DST in FM patients with depression (p = 0.03; z: -2.165), but not in those without depression (p = 0.15 3 ; z: -1.429). The cortisol level was not found to be statistically significant when patients with FM without depression were compared with the control group (p = 0.249 z: -1.152). In 7 FM patients with depression the DST failed to suppress cortisol; this was statistically significant compared with FM patients without depression (p = 0.014) and the control group (p = 0.008). Among FM patients without depression cortisol was not suppressed in one case. Cortisol was suppressed in all the controls. There was no statistically significant difference in cortisol suppression between FM patients without depression and the control group (p = 1.00). Conclusion: Our findings show that the DST reveals no neurobiological relationship between FM and depression related to the HPA axis

The association between Internet addiction and dissociation among Turkish college students

WOS: 000305769000002PubMed: 22000475Purpose: This study aimed to investigate Internet use patterns and Internet addiction among young adult university students and to examine the correlation between excessive Internet use and dissociative symptoms. Methods: The study was conducted among 1034 students, aged between 18 and 27 years. Internet Addiction Scale, Dissociative Experiences Scale, and a sociodemographic query form were used in the collection of data. Pearson correlation analysis, the t test, and chi(2) test were used for data analysis. Results: According to the Internet Addiction Scale, 9.7% of the study sample was addicted to the Internet. The Pearson correlation analysis results revealed a significant positive correlation between dissociative experiences and Internet addiction (r = 0.220; P < .001) and weekly Internet use (r = 0.227; P < .001). Levels of Internet addiction were significantly higher among male students than female students (P <.001). The Internet use pattern also differed significantly between sexes. Conclusions: According to the results of this study, Internet addiction is a relatively frequent phenomenon among young adult college students in Turkey. Excessive Internet use is associated with higher levels of dissociative symptoms. (C) 2012 Elsevier Inc. All rights reserved