Duygusal özerklik kazanımında benlik saygısı ve karar verme stillerinin etkilerinin belirlenmesi

Bu tez çalışmasının amacı, karar vermede benlik saygısı ve karar verme stillerinin duygusal özerklik alt boyutları ile olan ilişki ve etkisini incelemektir. Ayrıca duygusal özerklik alt boyutları ve karar verme stillerinin çeşitli sosyodemografik değişkenler ile olan ilişkisi de araştırma kapsamındadır. Çalışmaya 16-24 yaş arasında toplam 366 lise ve üniversite öğrencisi katılmıştır. Katılımcıların %55,2’si kız (n = 202), %44,8’i (n = 164) erkek ve yaş ortalaması 19,07±2,49’dur. Bunların %42,9’u lise öğrencisi (n = 157), %12,6’sı ön lisans öğrencisi (n = 46) ve %44,5’i lisans (n = 163) öğrencisidir. Araştırmada “Duygusal Özerklik Ölçeği” ve “Melbourne Karar Verme Ölçeği-I-II” kullanılmıştır. Verilerin analizinde tek yönlü varyans analizi, Pearson korelasyon ve çoklu doğrusal regresyon analizleri kullanılmıştır. Analizler, duygusal özerkliğin cinsiyet, yaş, kardeş sayısı, yaşanılan yer ve aile durumu değişkenlerine göre farklılaştığını ortaya koymaktadır. Araştırma sonuçlarına göre, karar vermede benlik saygısı, dikkatli ve panik karar verme stillerinin duygusal özerkliğin alt boyutlarını yordadığı görülmüştür. Elde edilen bulgular, karar verme stillerinin duygusal özerkliğin alt boyutları üzerindeki etkisinin ergenliğin orta ve geç dönemlerinde değişim gösterdiğini kanıtlamaktadır.The purpose of this thesis is to examine the relationship and influence of selfesteem in decision-making and emotional autonomy sub-dimensions of decisionmaking styles. In addition, the relationship between emotional autonomy subdimensions and decision-making styles with various socio-demographic variables is also included. A total of 366 high school and university students between the ages of 16 and 24 participated in the study. 55.2% of the participants were female (n = 202), 44.8% (n = 164) were male and the mean age was 19.07±2.49. Of these, 42.9% were high school students (n = 157), 12.6% were associate degree students (n = 46) and 44.5% were undergraduate students (n = 163). "Emotional Autonomy Scale" and "Melbourne Decision Making Scale-I-II" were used in the research. One-way ANOVA, Pearson correlation and multiple lineer regression analyzes were used in the analysis of the data. Analyzes show that emotional autonomy varies according to gender, age, number of siblings, place of residence and family situation. According to the results of the research, self-esteem in decision making, vigilance and hypervigilange decision-making styles predicted subscale dimensions of emotional autonomy. Findings show that the effect of decision-making styles on the subdimensions of emotional autonomy changes during middle and late adolescence

Measuring Alexithymia via Trait Approach-I: A Alexithymia Scale Item Selection and Formation of Factor Structure

Introduction: It is not clear in the literature whether available instruments are sufficient to measure alexithymia because of its theoretical structure. Moreover, it has been reported that several measuring instruments are needed to measure this construct, and all the instruments have different error sources. The old and the new forms of Toronto Alexithymia Scale are the only instruments available in Turkish. Thus, the purpose of this study was to develop a new scale to measure alexithymia, selecting items and constructing the factor structure. Methods: A total of 1117 patients aged from 19 to 82 years (mean = 35.05 years) were included. A 100-item pool was prepared and applied to 628 women and 489 men. Data were analyzed using Explanatory Factor Analysis, Confirmatory Factor Analysis, and Item Response Theory and 28 items were selected. The new form of 28 items was applied to 415 university students, including 271 women and 144 men aged from 18 to 30 (mean=21.44).Results: The results of Explanatory Factor Analysis revealed a five-factor construct of "Solving and Expressing Affective Experiences,” "External Locused Cognitive Style,” "Tendency to Somatize Affections,” "Imaginary Life and Visualization,” and "Acting Impulsively,” along with a two-factor construct representing the "Affective” and "Cognitive” components. All the components of the construct showed good model fit and high internal consistency. The new form was tested in terms of internal consistency, test-retest reliability, and concurrent validity using Toronto Alexithymia Scale as criteria and discriminative validity using Five-Factor Personality Inventory Short Form. Conclusion: The results showed that the new scale met the basic psychometric requirements. Results have been discussed in line with related studies

Panax ginseng extract ameliorates methotrexate-induced multi-organ damage via the regulation of oxidative stress

Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and kidney damage. Twenty-four Sprague Dawley male rats (weight 250-300 g) were used in the study. The animals were randomly separated into three groups: a) Control, b) MTX-treated (MTX) and c) MTX+PxG-treated (MTX+PxG) groups. MTX was administered intraperitoneally at 20 mg/kg, as a single dose to MTX and MTX+PxG groups. PxG was administered orally at 100 mg/kg to the MTX+PxG group for five days. Saline was given to the control and MTX groups for 5 days. At the end of the experiment, liver, lung, ileum, and kidney samples were obtained. Malondialdehyde (MDA) and glutathione (GSH) levels, superoxide dismutase (SOD), glutathione-S-transferase (GST) and tissue factor (TF) activities were determined in all tissues. In addition, histological examinations were done through light microscopy. GraphPad Prism 5v. was used for statistics, and p[removed]