A Comparison of Three QRS Detection Algorithms Over a Public Database

AbstractWe have compared three of the best QRS detection algorithms, regarding their results, to check the performance and to elucidate which get better accuracy. In the literature these algorithms were published in a theoretical way, without offering their code, so it is difficult to check its real behaviour over different collections of ECG records. This work brings the community our source code of each algorithm and results of its validation over a public database. In addition, this software was developed as a framework in order to permit the inclusion of new QRS detection algorithms and also its testing over different databases

Clinical-epidemiological characterization of complicated community-acquired pneumonia in children admitted to the Intensive Care Unit of the “Pepe Portilla” Pediatric Hospital

Introduction: Acute respiratory infections constitute a serious health problem as they are the main cause of infant morbidity and mortality in the world, mainly during the first year of life. Objective: To clinically and epidemiologically characterize complicated community pneumonias in children admitted to the Intensive Care Unit of the "Pepe Portilla" Pediatric Hospital. Methods: An observational, descriptive, cross-sectional, descriptive study was carried out on 80 patients with pneumonia complicated by pleural effusion, admitted to the Intensive Care Unit of the "Pepe Portilla" Pediatric Hospital. Results: children from 0 to 4 years of age were more affected (77,5 %), with a slight predominance of the male sex (60 %). Fever and polypnea were present in 15 % of the patients' symptoms. Streptococcus pneumoniae (8,7 %) was the predominant germ in pleural fluid. The combination of antibiotics and fibrinolytics (91,3 %) was the predominant therapeutic combination. Sepsis was the most common complication (22,5 %). The length of stay with most patients was < 10 days (81,3 %). Conclusions: the most affected age group was 0-4 years of age, the predominant sex was male, the predominant symptoms were fever and polypnea, Streptococcus pneumoniae was the microorganism responsible for the appearance of this disease, the use of antibiotics plus fibrinolytics was necessary, sepsis predominated as the most severe complication and the hospital stay in said unit was less than 10 days

Epistemological approach to the process of training of the pedagogical terminology of the students of Medical Sciences

Introduction: the main results of different authors are addressed in relation to the vocabulary as a unit of language. The peculiarities of the pedagogical terminology are established and the pertinence of it is established in the training process of medical students. Objective: to analyze epistemologically the main theoretical references that are addressed both in the national and international literature in relation to the pedagogical terminology and its importance in the training of medical students. Method: the documentary analysis and the systematization were used as theoretical methods, which allowed organizing and extracting the relevant information, from the literature review made on the theme, which favored the arguments on the role of the process of training of the pedagogical terminology and reaching a contextualized definition of this process. Results: the pedagogical terminology is defined, and contextualized to the medical studies from the correspondence with the professional model, the integration of the training processes, and the enhancement of the cognitive and affective development of the student. Conclusions: it is considered that the pedagogical terminology is an important component in the act of pedagogical communication, as it is the structure of the specialized expression, both oral and writing which reflecting the knowledge related to the profession, as well as the specific historical environment in which it spreads out, unifying the cognitive and the social aspects

Aproximación epistemológica al proceso de formación del léxico pedagógico de los estudiantes de Ciencias Médicas

Introduction: the main results of different authors are addressed in relation to the vocabulary as a unit of language. The peculiarities of the pedagogical terminology are established and the pertinence of it is established in the training process of medical students.Objective: to analyze epistemologically the main theoretical references that are addressed both in the national and international literature in relation to the pedagogical terminology and its importance in the training of medical students.Method: the documentary analysis and the systematization were used as theoretical methods, which allowed organizing and extracting the relevant information, from the literature review made on the theme, which favored the arguments on the role of the process of training of the pedagogical terminology and reaching a contextualized definition of this process.Results: the pedagogical terminology is defined, and contextualized to the medical studies from the correspondence with the professional model, the integration of the training processes, and the enhancement of the cognitive and affective development of the student.Conclusions: it is considered that the pedagogical terminology is an important component in the act of pedagogical communication, as it is the structure of the specialized expression, both oral and writing which reflecting the knowledge related to the profession, as well as the specific historical environment in which it spreads out, unifying the cognitive and the social aspects.Introducción: se abordan los principales resultados de diferentes autores en relación con el léxico como unidad de la lengua. Se establecen las particularidades del léxico pedagógico y se argumenta la pertinencia del mismo en el proceso formativo de los estudiantes de las carreras médicas.Objetivo: analizar epistemológicamente los principales referentes teóricos que se abordan tanto en la literatura nacional como internacional en relación con el léxico pedagógico y su importancia en la formación de los estudiantes de las carreras médicas.Método: se emplearon como métodos de orden teórico el análisis documental y la sistematización, los cuales permitieron organizar y extraer información relevante, a partir de la revisión bibliográfica realizada sobre el tema, lo que favoreció la argumentación sobre el papel del proceso de formación del léxico pedagógico y arribar a una definición contextualizada de dicho proceso.Resultados: se define el léxico pedagógico, contextualizado a las carreras médicas desde la correspondencia con el modelo del profesional, la integración de procesos formativos, y la potenciación del desarrollo cognitivo y afectivo del estudiante.Conclusiones: se considera que el léxico pedagógico es un componente importante en el acto de comunicación pedagógica, por cuanto es la forma de expresión especializada tanto oral como escrita que refleja el conocimiento relacionado con la profesión, así como del medio histórico concreto en que se desenvuelve, unificando lo cognoscitivo y lo social

Questionnaire of Empathy and Violence: Pilot Psychometric Study

Marco teórico: En las últimas décadas, ha aumentado exponencialmente la investigación sobre la relación entre la empatía y la violencia. Hay estudios que señalan correlaciones negativas entre la empatía y las conductas violentas, disruptivas, criminales, antisociales o agresivas. El objetivo de este estudio consistió en el diseño de un cuestionario para evaluar el grado de empatía y violencia en una misma escala. Métodos: Para ello, se ha utilizado un conjunto de 13 ítems y X variables sociodemográficas, de los cuales, 7 de ellos están relacionados con la empatía y 6 con la violencia. Inicialmente se utilizó una muestra incidental compuesta por 297 participantes (89 hombres y 208 mujeres) con edades a partir de los 18 años. Para la realización de este estudio se extrajo un muestra aleatoria del 25% de la muestra total inicial. Resultados: Se realizaron análisis de frecuencia, de fiabilidad, de correlaciones y un análisis factorial exploratorio. Este ofreció como resultado la extracción de dos factores denominados empatía(factor 1) y violencia(factor 2) los cuales explican el 67% de la varianza de los datos originales. Como resultado se realiza un nuevo Cuestionario de Empatía y Violencia (CEV) compuesto por 8 ítems y X variables sociodemográficas. Conclusiones: Este CEV se corrobora como un instrumento en castellano, mostrando unas propiedades psicométricas adecuadas para su utilización en el campo de la salud mental y se sugieren pasos a seguir para futuras investigacionesTheoretical Framework:In the last decades, the relationship between empathy and violence has increased exponentially. There are studies that point out negative relationship between empathy and violent behaviors, disruptive, criminal or aggressiveness. The objective of this study was to design a questionnaire to assess the degree of empathy and violence on the same scale. Methods:To do this,it used a set of 13 items and X sociode-mographic variables, of which 7 of them are rela-ted to empathy and 6 to violence. Initially it used an incidental sample composed of 297 partici-pants (89 men and 208 women) with ages starting at 18 years is used. For the realization of this pilot study, a random sample of 25%was extracted from the initial total sample.Results:Analysis of fre-quencies, reliability, correlations and factorial exploratory analysis was carried out. This yields the extraction of two factors named empathy (factor 1) and violence (factor 2) which explain the 67% of the variance of the original data. As a result, a new Empathy and Violence Questionnaire (CEV), consisting of 8 items and X sociodemo-graphic variables, was created. Conclusions:The CEV confirms that, as a Castilian instrument, it shows some psychometric properties suitable for its utilization in the mental health field, and it suggests steps for future investigation

Heart of Darkness: Heart Rate Variability on Patients with Risk of Suicide

Heart Rate Variability (HRV) is an emerging research field in the study of diverse pathologies, as long as it allows considering another measurement for detecting possible aggravations. The aim of this work is to study the applicability of the analysis of HRV in order to establish if a person is at risk of suffering from suicidal ideation. This work includes the development and testing of a heart rate acquisition and automatic analysis system, with friendly software for clinicians, customized to the necessities of an emergency unit. Furthermore, it includes the analysis of the obtained data with the purpose of assessing possible correlations between HRV parameters and personality impulsive traits. 20 patients and 10 normal cases were selected to develop this pilot study. Results show significant statistical difference (p<0.05) among patients and normal cases for pNN50, IRRR, MADRR, total HRV power, Approximate Entropy and Fractal Dimension

Guidelines to develop demonstration models on industry 4.0 for engineering training

[EN] Industrial digitization is currently a great challenge which involves continuous advances in tech-nologies such as automation, robotics, internet of things, cloud computing, big data, virtual and augmented reality or cybersecurity. Only those companies able to adapt and with qualified work-ers will be competitive. Therefore, it is necessary to design new environments to train students and workers in these enabling technologies. In this paper, a set of guidelines is proposed to develop a demonstration model on Industry 4.0. Following these guidelines, an existing manufacturing industrial system, based on an electro-pneumatic cell for classifying pieces, is updated to the Industry 4.0 paradigm. The result is an Industry 4.0 demonstration model where enabling tech-nologies are added in an integrated way. In this manner, students do not only train in each technology, but also understand the interactions between them. In the academic year 2020/21, this demonstration model has been used by engineering students in a subject of a master’s degree. Impressions and comments from students about the structure and management of the environ-ment, as well as the influence on their learning process are collected and discussed.SIThis work was supported by the Spanish State Research Agency, MCIN/AEI/10.13039/501100011033 under Grant PID2020-117890RB-I00. The work of José Ramón Rodríguez- Ossorio was supported by a grant of the Research Programme of the Universidad de León 2020. The work of Guzmán González-Mateos was supported by a grant of the Research Programme of the University of León 202

Drug Delivery from Hyaluronic Acid-BDDE Injectable Hydrogels for Antibacterial and Anti-Inflammatory Applications

Hyaluronic acid (HA) injectable biomaterials are currently applied in numerous biomedical areas, beyond their use as dermal fillers. However, bacterial infections and painful inflammations are associated with healthcare complications that can appear after injection, restricting their applicability. Fortunately, HA injectable hydrogels can also serve as drug delivery platforms for the controlled release of bioactive agents with a critical role in the control of certain diseases. Accordingly, herein, HA hydrogels were crosslinked with 1 4-butanediol diglycidyl ether (BDDE) loaded with cefuroxime (CFX), tetracycline (TCN), and amoxicillin (AMX) antibiotics and acetylsalicylic acid (ASA) anti-inflammatory agent in order to promote antibacterial and anti-inflammatory responses. The hydrogels were thoroughly characterized and a clear correlation between the crosslinking grade and the hydrogels’ physicochemical properties was found after rheology, scanning electron microscopy (SEM), thermogravimetry (TGA), and differential scanning calorimetry (DSC) analyses. The biological safety of the hydrogels, expected due to the lack of BDDE residues observed in 1H-NMR spectroscopy, was also corroborated by an exhaustive biocompatibility test. As expected, the in vitro antibacterial and anti-inflammatory activity of the drug-loaded HA-BDDE hydrogels was confirmed against Staphylococcus aureus by significantly decreasing the pro-inflammatory cytokine levels.This research was funded by the i+Med S. Coop., Basque Government (FRONTIERS project, ELKARTEK program, HAZITEK program: IMABI exp number ZE-2019/00012), and the Department of Development and Infrastructures of the Basque Country. Jon Andrade del Olmo thanks the Basque Government for the “Program of Industrial Doctorates. Bikaintek 2018” (exp. number 01-AF-W2-2018-00002)

Identification of Smith–Magenis syndrome cases through an experimental evaluation of machine learning methods

This research work introduces a novel, nonintrusive method for the automatic identification of Smith–Magenis syndrome, traditionally studied through genetic markers. The method utilizes cepstral peak prominence and various machine learning techniques, relying on a single metric computed by the research group. The performance of these techniques is evaluated across two case studies, each employing a unique data preprocessing approach. A proprietary data “windowing” technique is also developed to derive a more representative dataset. To address class imbalance in the dataset, the synthetic minority oversampling technique (SMOTE) is applied for data augmentation. The application of these preprocessing techniques has yielded promising results from a limited initial dataset. The study concludes that the k-nearest neighbors and linear discriminant analysis perform best, and that cepstral peak prominence is a promising measure for identifying Smith–Magenis syndrome