Computer program for crossed-beam studies of clear air turbulence, Program description /MLTCOR/ Final report, 14 May 1968 - 13 Aug. 1969

Computer program for studies of aerodynamic and clear atmospheric turbulenc

“Immunology of music”? A short introduction to cognitive science of musical improvisation

Studies on music in the area of cognitive sciences – quite varied despite their short history – meet with scepticism. The author of this introduction, presenting some spectacular examples of research on musical improvisation, tries to demonstrate that they enrich rather than reduce our understanding of this phenomenon

A High-Throughput Approach to Characterizing ARV1 on the Regulation of Lipid Homeostasis Uncovers a Novel Interaction with Epidermal Growth Factor Receptor

Acyl-CoA cholesterol acyl transferase related enzyme-2 required for viability 1 (ARV1) was first recognized in Saccharomyces cerevisiae in a study done in 2000 by Tinkelenberg et al. In yeast, the deletion of ARV1 results in numerous defects including abnormal sterol trafficking [1], the reduction of sphingolipid metabolism [2], synthesis of glycosylphosphatidylinositol (GPI) anchor [3], ER stress [4], and hypersensitivity of fatty acids leading to lipoapoptosis [5]. Arv1 germline deletion in mice displayed a lean phenotype with increased energy [6]. In humans, ARV1 mutations lead to epileptic encephalopathy [7]. Non-alcoholic fatty liver disease (NAFLD) consists of simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma [8]. NAFLD is the most common liver disease worldwide affecting 25% of the global population and 33% of the population in the United States [8]. NAFLD is on the rise due to irresponsible dietary and sedentary lifestyles. Currently, there is not a pharmacological treatment for NAFLD. The specific aims include the generation of ARV1 over expression and ARV1 knockout in HepG2 cells, to investigate gene expression profiles in each respective ARV1 cell line using Qiagen RT2 Profiler arrays and to identify novel pathways to validate Arv1 function in HepG2 cells. We found ARV1 over expression cells to be lipotoxic in HepG2 cells. We showcased EGFR phosphorylation of Arv1. We observed two different EGFR inhibitors where both “rescued” toxicity in Arv1 over expression cells

Slave Diet in the Antebellum South

The event will be a presentation of paper written on the varied diet of slaves and their acquisition of food during the antebellum south

Wybrana. Wywiad z Różą Puzynowską

Wywiad z Różą Puzynowską. Przeprowadził Witold Wachowski

The AIDS Virus and the Galvanization of the LGBTQ Movement for Equality

The LGBTQ community was greatly altered by the AIDS crisis and the organizations that were founded in the 1980s. AIDS would become associated with those of the gay community during the early years of the crisis. The government and leading health officials perpetuated the public’s ignorance about the relativity new disease leading to more misunderstandings and mishandlings of the HIV/AIDS crisis. The disease did not discriminate among people, however, and quickly spread throughout many of the communities in the U.S. Organizations with roots in the LGBTQ community established themselves during the 1980s to deal with not only the AIDS crisis, but also the issues that arose in the community. GMHC (Gay Men’s Health Crisis), sought to help those who had fallen ill with AIDS, and spread information on AIDS. ACT UP (AIDS Coalition to Unleash Power), fought for the rights of those with AIDS. GLAAD (Gay & Lesbian Alliance Against Defamation) sought change for the betterment of the LGBTQ community, and fought against defamation of the community. The NAMES Project brought those who lost loved ones to AIDS together to heal in a visible way. The organizations had a profound impact on the LGBTQ community expanding beyond the 1980s and into the present. The AIDS crisis of the 1980s took its toll on a generation of people, and disproportionately punished the gay male population in America. Throughout the mishandling of the crisis by the U.S. government and the medical community, leaders and organizations arose to deal with the crisis. First led by gay men, a movement emerged to deal with the disease, and through their work began to work for rights for the larger LGTBQ community. The AIDS crisis, as terrible as it was, spawned a larger movement that would begin to work for equality for the LGTBQ community. These efforts would include working for better healthcare, changing legislation iii that discriminated against gays and lesbians, and pressing for full inclusion of the LGTBQ community into American society

Notes on conformal anomaly, nonlocal effective action and the metamorphosis of the running scale (to the memory of Stanley Deser)

We discuss the structure of nonlocal effective action generating the conformal anomaly in classically Weyl invariant theories in curved spacetime. By the procedure of conformal gauge fixing, selecting the metric representative on a conformal group orbit, we split the renormalized effective action into anomalous and Weyl invariant parts. A wide family of thus obtained anomalous actions is shown to include two special cases of Riegert--Fradkin--Tseytlin and Fradkin--Vilkovisky actions. Both actions are shown to be contained in the first three orders of the curvature expansion for a generic one-loop effective action obtained by covariant perturbation theory. The complementary Weyl invariant part of the action is given by the ``conformization'' of the full effective action -- restricting its argument to the conformally invariant representative of the orbit of the conformal group. This is likely to resolve a long-standing debate between the proponents of the Riegert action and adherents of the perturbation expansion for the effective action with typical nonlocal logarithmic form factors. We derive the relation between quantum stress tensors on conformally related metric backgrounds, which generalizes the known Brown-Cassidy equation to the case of nonzero Weyl tensor, and discuss applications of this relation in the cosmological model driven by conformal field theory. We also discuss the issue of renormalization group running for the cosmological and gravitational coupling constants and show that it exhibits a kind of a metamorphosis to the nonlocal form factors of the so-called partners of the cosmological and Einstein terms -- nonlocal curvature squared terms of the effective action.Comment: 26 page

Sztuka antropotechniczna

Wywiad z Agnieszką Jelewską. Rozmawiają: Monika Włudzik i Witold Wachowski

AnthropoTechne Art

Interview with Agnieszka Jelewska by Monika Włudzik and Witold Wachowski