Le pubblicazioni dell’Istituto per l’Europa orientale

With the additional help of archival material, the first part of this volume reconstructs the history of the Institute for Eastern Europe (Ipeo), founded in Rome in 1921, whose activity was characterized by a remarkable editorial production closely connected to the birth and development of Italian Slavic Studies. Despite the inevitable coexistence with fascism and the submission, somehow, to a line of conduct which especially in the 1930s accompanied the regime’s policy, the Ipeo’s activity was marked above all by a sincere desire to spread knowledge of a world which was still quite unknown in the Italian context under many aspects. The Ipeo operated until the end of World War II, when the government funding and even the political and cultural assumptions which had favoured its birth ceased because of the changed geopolitical context, determined by the end of the conflict. The second part of the volume covers the General alphabetical catalogue of all Ipeo’s publications, accompanied by a Chronological catalogue and by an Index of authors, editors, translators and preface writers

Appropriateness of antiplatelet therapy for primary and secondary cardio- and cerebrovascular prevention in acutely hospitalized older people

Aims: Antiplatelet therapy is recommended for the secondary prevention of cardio- and cerebrovascular disease, but for primary prevention it is advised only in patients at very high risk. With this background, this study aims to assess the appropriateness of antiplatelet therapy in acutely hospitalized older people according to their risk profile. Methods: Data were obtained from the REPOSI register held in Italian and Spanish internal medicine and geriatric wards in 2012 and 2014. Hospitalized patients aged 6565 assessable at discharge were selected. Appropriateness of the antiplatelet therapy was evaluated according to their primary or secondary cardiovascular prevention profiles. Results: Of 2535 enrolled patients, 2199 were assessable at discharge. Overall 959 (43.6%, 95% CI 41.5\u201345.7) were prescribed an antiplatelet drug, aspirin being the most frequently chosen. Among patients prescribed for primary prevention, just over half were inappropriately prescribed (52.1%), being mainly overprescribed (155/209 patients, 74.2%). On the other hand, there was also a high rate of inappropriate underprescription in the context of secondary prevention (222/726 patients, 30.6%, 95% CI 27.3\u201334.0%). Conclusions: This study carried out in acutely hospitalized older people shows a high degree of inappropriate prescription among patients prescribed with antiplatelets for primary prevention, mainly due to overprescription. Further, a large proportion of patients who had had overt cardio- or cerebrovascular disease were underprescribed, in spite of the established benefits of antiplatelet drugs in the context of secondary prevention