731 research outputs found

    A Possible Case of Neurogenic Pulmonary Edema in a Sheep following Intracranial Surgery

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    A 3-year-old female crossbred sheep weighing 64 kg was anaesthetized for intracranial surgery as a part of a research project. Premedication and induction of anesthesia were uneventful as well as tracheal intubation. Anesthesia was maintained with isoflurane in a 50% mixture of oxygen and air, fentanyl (5-15 µg kg-1h-1) and lidocaine (1.8 mg kg-1h-1). During anesthesia, an increased alveolar-arterial oxygen gradient was calculated on the basis of arterial blood gas analysis: inspiratory fraction of oxygen was increased and a recruitment manoeuvre was performed. After 210 minutes of anesthesia, the sheep was let recover with oxygen supplementation under monitoring of pulse-oxymetry, capnography, inspired and expired oxygen, temperature and invasive blood pressure. At tracheal extubation no signs of regurgitation or aspiration were noticed. Twenty-five minutes later, the sheep showed deterioration of neurological status and clonic seizure responsive to diazepam. After transient tachycardia, blood pressure rose acutely and sinus bradycardia followed. Severe tachypnea started in few minutes accompanied by loud respiratory noises and harsh diffuse crackles on both sides of the thorax. Foamy blood nasal exudates discharged from the nostrils. Neurogenic pulmonary edema as a sequel of increased intracranial pressure was suspected and treated with intravenous mannitol (0.5 gkg-1) and furosemide (4 mgKg-1). Hypoxemia was successfully managed with oxygen supplementation. Motor and cognitive functions improved progressively and were deemed normal within 12 hours from the episode, when arterial partial pressure of oxygen was 11.7 kPa (88 mmHg) at room air

    Islands of Innovation and Internationally Networked Labor Markets: Magnetic Centers for Star Scientists?

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    Top researchers and outstanding scientists are an essential source of science-based innovation and regional development. The location pattern and international movements of the scientific elite, are, thus, of fundamental importance. However, despite a growing interest, there is only little empirical evidence about these core issues. Drawing on the results of a world-wide survey of 720 ?star scientists? (identified by the number of citations they generated in journals in the ISI databases in the period 1981-2002) this paper seeks to explore the role of islands of innovation in providing employment opportunities for stars. It is shown that US and European islands of innovation and their regional labor markets are at the forefront when it comes to produce (i.e. to educate) and to employ star scientists and to exchange them with other places. Furthermore, the paper provides evidence for the formation of a network among innovative regional labor markets based on international movements of the best and brightest scientific minds.islands of innovation, innovative regional labor markets, star scientists, scientific mobility

    Geographic Differences in the Relative Price of Healthy Foods

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    Although healthy foods can be affordable, if less healthy foods are cheaper, individuals may have an economic incentive to consume a less healthful diet. Using the Quarterly Food-at-Home Price Database, we explore whether a select set of healthy foods (whole grains, dark green vegetables, orange vegetables, whole fruit, skim and 1% milk, fruit juice, and bottled water) are more expensive than less healthy alternatives. We find that not all healthy foods are more expensive than less healthy alternatives; skim and 1% milk are less expensive than whole and 2% milk and bottled water is generally less expensive than carbonated nonalcoholic drinks. We also find considerable geographic variation in the relative price of healthy foods. This price variation may contribute to geographic variation in diet and health outcomes.Quarterly Food-at-Home Price Database (QFAHPD), healthy food, price, geographic variation, Agricultural and Food Policy, Consumer/Household Economics, Demand and Price Analysis, Food Consumption/Nutrition/Food Safety, Health Economics and Policy, Public Economics,

    Labor Conditions in the Nicaraguan Sugar Industry

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    ILRF_nicaragua_sugar.pdf: 465 downloads, before Oct. 1, 2020

    A method for the determination of potentially profitable service patterns for commuter air carriers

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    A methodology for estimating market conception was developed as a part of the short-haul air transportation program. It is based upon an analysis of actual documents which provide a record of known travel history. Applying this methodology a forecast was made of the demand for an air feeder service between Charlottesville, Virginia and Dulles International Airport. Local business travel vouchers and local travel agent records were selected to provide the documentation. The market was determined to be profitable for an 8-passenger Cessna 402B aircraft flying a 2-hour daily service pattern designed to mesh to the best extent possible with the connecting schedules at Dulles. The Charlottesville - Dulles air feeder service market conception forecast and its methodology are documented

    Biopharmaceutics

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