2,003,654 research outputs found

    On convergence of generalized continued fractions and Ramanujan's conjecture

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    We consider continued fractions \frac{-a_1}{1-\frac{a_2}{1-\frac{a_3}{1-...}}} \label{fr} with real coefficients aia_i converging to a limit aa. S.Ramanujan had stated the theorem (see [ABJL], p.38) saying that if a14a\neq\frac14, then the fraction converges if and only if a<14a<\frac14. The statement of convergence was proved in [V] for complex aia_i converging to aC[14,+)a\in\mathbb C\setminus[\frac14,+\infty) (see also [P]). J.Gill [G] proved the divergence of (\ref{fr}) under the assumption that aia>14a_i\to a>\frac14 fast enough, more precisely, whenever \sum_i|a_i-a|<\infty.\label{gill} The Ramanujan conjecture saying that (\ref{fr}) diverges always whenever aia>14a_i\to a>\frac14 remained up to now an open question. In the present paper we disprove it. We show (Theorem \ref{th1}) that for any a>14a>\frac14 there exists a real sequence aiaa_i\to a such that (\ref{fr}) converges. Moreover, we show (Theorem \ref{go}) that Gill's sufficient divergence condition (\ref{gill}) is the optimal condition on the speed of convergence of the aia_i's.Comment: Submitted to C.R.A.S. on December 23, 200

    Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients?

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    The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref. 8). SPM-1, a recently discovered MBL, was isolated from a juvenile leukemia patient residing in a hospital in San Palo, Brazil just prior to the patient succumbing to septicemia brought on by Pseudomonas aeruginosa expressing SPM-1 (ref. 8). Screening of the Johns Hopkins Compound library of 1,514 FDA or FAD approved drugs (ref. 1) identified a novel SPM-1 inhibitor that is synergistically compatible with meropenem. Using clinically achievable concentrations, meropenem coupled with nadifloxacin inhibits Pseudomonas aeruginosa expressing SPM-1. This shotgun approach to new drug discovery provided a prompt solution to the grave problem of antibiotic resistant pathogens that are thriving in hospitals today

    2014 Maintenance Agenda

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    Asks questions about the proper reporting of premium receivable with credit balances on group contracts (gross or net reporting

    Phosphomannosylation and the functional analysis of the extended Candida albicans MNN4-like gene family

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    We thank Luz A. López-Ramírez (Universidad de Guanajuato) for technical assistance. This work was supported by Consejo Nacional de Ciencia y Tecnología (ref. CB2011/166860; PDCPN2014-247109, and FC 2015-02-834), Universidad de Guanajuato (ref. 000025/11; 0087/13; ref. 1025/2016; Convocatoria Institucional para Fortalecer la Excelencia Académica 2015; CIFOREA 89/2016), Programa de Mejoramiento de Profesorado (ref. UGTO-PTC-261), and Red Temática Glicociencia en Salud (CONACYT-México). NG acknowledges the Wellcome Trust (086827, 075470, 101873, and 200208) and MRC Centre for Medical Mycology for funding (N006364/1). KJ was supported by a research visitor grant to Aberdeen from China Scholarship Council (CSC No. 201406055024). The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmicb.2017.02156/full#supplementary-materialPeer reviewedPublisher PD

    Comment on "PT Symmetry as a Generalization of Hermiticity" [arXiv:1002.2676]

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    We notice that the general PT-symmetric Hamiltonian matrix(N=2) having 6-real parameters fails to reproduce one parameter PT-symmetric matrix.Comment: Title unchanged ,one ref [5] added . Abstract changed . All the previous matrices have been changed consideing the ref[5

    On the isomorphism problem of concept algebras

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    Weakly dicomplemented lattices are bounded lattices equipped with two unary operations to encode a negation on {\it concepts}. They have been introduced to capture the equational theory of concept algebras \cite{Wi00}. They generalize Boolean algebras. Concept algebras are concept lattices, thus complete lattices, with a weak negation and a weak opposition. A special case of the representation problem for weakly dicomplemented lattices, posed in \cite{Kw04}, is whether complete {\wdl}s are isomorphic to concept algebras. In this contribution we give a negative answer to this question (Theorem \ref{T:main}). We also provide a new proof of a well known result due to M.H. Stone \cite{St36}, saying that {\em each Boolean algebra is a field of sets} (Corollary \ref{C:Stone}). Before these, we prove that the boundedness condition on the initial definition of {\wdl}s (Definition \ref{D:wdl}) is superfluous (Theorem \ref{T:wcl}, see also \cite{Kw09}).Comment: 15 page
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