15,685 research outputs found

    A smartphone-based tool for rapid, portable, and automated wide-field retinal imaging

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    Enhancing retinal images by nonlinear registration

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    Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few. In this paper, we propose to share the knowledge acquired in the fields of optics and imaging in solar astrophysics in order to improve the retinal imaging at very high spatial resolution in the perspective to perform a medical diagnosis. The main purpose would be to assist health care practitioners by enhancing retinal images and detect abnormal features. We apply a nonlinear registration method using local correlation tracking to increase the field of view and follow structure evolutions using correlation techniques borrowed from solar astronomy technique expertise. Another purpose is to define the tracer of movements after analyzing local correlations to follow the proper motions of an image from one moment to another, such as changes in optical flows that would be of high interest in a medical diagnosis.Comment: 21 pages, 7 figures, submitted to Optics Communication

    Response for light scattered in the ocular fundus from double-pass and Hartmann–Shack estimations

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    Double-pass (DP) and Hartmann--Shack (HS) are complementary techniques based on reflections of light in the ocular fundus that may be used to estimate the optical properties of the human eye. Under conventional data processing, both of these assessment modes provide information on aberrations. In addition, DP data contain the effects of scattering. In the ocular fundus, this phenomenon may arise from the interaction of light with not only the retina, but also deeper layers up to which certain wavelengths may penetrate. In this work, we estimate the response of the ocular fundus to incident light by fitting the deviations between DP and HS estimations using an exponential model. In measurements with negligible intraocular scattering, such differences may be related to the lateral spreading of light that occurs in the ocular fundus due to the diffusive properties of the media at the working wavelength. The proposed model was applied in young healthy eyes to evaluate the performance of scattering in such a population. Besides giving a parameter with information on the ocular fundus, the model contributes to the understanding of the differences between DP and HS estimations.Postprint (author's final draft
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