Vascular intersection detection in retina fundus images using a new hybrid approach

The use of vascular intersection aberration as one of the signs when monitoring and diagnosing diabetic retinopathy from retina fundus images (FIs) has been widely reported in the literature. In this paper, a new hybrid approach called the combined cross-point number (CCN) method able to detect the vascular bifurcation and intersection points in FIs is proposed. The CCN method makes use of two vascular intersection detection techniques, namely the modified cross-point number (MCN) method and the simple cross-point number (SCN) method. Our proposed approach was tested on images obtained from two different and publicly available fundus image databases. The results show a very high precision, accuracy, sensitivity and low false rate in detecting both bifurcation and crossover points compared with both the MCN and the SCN method

A new method of vascular point detection using artificial neural network

Vascular intersection is an important feature in retina fundus image (RFI). It can be used to monitor the progress of diabetes hence accurately determining vascular point is of utmost important. In this work a new method of vascular point detection using artificial neural network model has been proposed. The method uses a 5×5 window in order to detect the combination of bifurcation and crossover points in a retina fundus image. Simulated images have been used to train the artificial neural network and on convergence the network is used to test (RFI) from DRIVE database. Performance analysis of the system shows that ANN based technique achieves 100% accuracy on simulated images and minimum of 92% accuracy on RFI obtained from DRIVE database

A new method of vascular point detection using artificial neural network

Vascular intersection is an important feature in retina fundus image (RFI). It can be used to monitor the progress of diabetes hence accurately determining vascular point is of utmost important. In this work a new method of vascular point detection using artificial neural network model has been proposed. The method uses a 5x5 window in order to detect the combination of bifurcation and crossover points in a retina fundus image. Simulated images have been used to train the artificial neural network and on convergence the network is used to test (RFI) from DRIVE database. Performance analysis of the system shows that ANN based technique achieves 100% accuracy on simulated images and minimum of 92% accuracy on RFI obtained from DRIVE database

Retina fundus image mask generation using pseudo parametric modeling technique

ABSTRACT (abstract): The use of vascular intersection as one of the symptoms for monitoring and diagnosis of diabetic retinopathy from Fundus images have been widely reported in literatures. In this work, a new hybrid approach that makes use of three different methods of vascular intersection detection namely Modified Cross-Point Number (MCN), Combine Cross-Points Number (CCN) and Artificial Neural Network (ANN) technique is hereby proposed. Result obtained from the application of this technique to both simulated and experimental shows a very high accuracy and precision value in detecting both bifurcation and cross over points. Thus an improvement in bifurcation and vascular point detection and a good tool in the monitoring and diagnosis of diabetic retinopath

Detection of vascular intersection in retina fundus image using modified cross point number and neural network technique

Vascular intersection can be used as one of the symptoms for monitoring and diagnosis of diabetic retinopathy from fundus images. In this work we apply the knowledge of digital image processing, fuzzy logic and neural network technique to detect bifurcation and vein-artery cross-over points in fundus images. The acquired images undergo preprocessing stage for illumination equalization and noise removal. Segmentation stage clusters the image into two distinct classes by the use of fuzzy c-means technique, neural network technique and modified cross-point number (MCN) methods were employed for the detection of bifurcation and cross-over points. MCN uses a 5x5 window with 16 neighboring pixels for efficient detection of bifurcation and cross over points in fundus images. Result obtained from applying this hybrid method on both real and simulated vascular points shows that this method perform better than the existing simple cross-point number (SCN) method, thus an improvement to the vascular point detection and a good tool in the monitoring and diagnosis of diabetic retinopathy

Detection of vascular intersection in retina fundus

Vascular intersection can be used as one of the symptoms for monitoring and diagnosis of diabetic retinopathy from fundus images. In this work we apply the knowledge of digital image processing, fuzzy logic and neural network technique to detect bifurcation and vein-artery cross-over points in fundus images. The acquired images undergo preprocessing stage for illumination equalization and noise removal. Segmentation stage clusters the image into two distinct classes by the use of fuzzy c-means technique, neural network technique and modified cross-point number (MCN) methods were employed for the detection of bifurcation and cross-over points. MCN uses a 5x5 window with 16 neighboring pixels for efficient detection of bifurcation and cross over points in fundus images. Result obtained from applying this hybrid method on both real and simulated vascular points shows that this method perform better than the existing simple cross-point number (SCN) method, thus an improvement to the vascular point detection and a good tool in the monitoring and diagnosis of diabetic retinopathy

Classification of retinal images based on statistical moments and principal component analysis

Early diagnosis of Diabetic Retinopathy (DR) has been suggested as a good measure of preventing blindness associated with Diabetes. Some of the reported methodologies of Retinal Images (RI) classification for early diagnosis of DR have been shown to involve several steps and approaches for effective and accurate diagnosis. Thus, this paper investigates the classification of RI using a two-stage procedure. The first stage includes the extraction of blood vessels from RI belonging to healthy and diabetes retinal images using a modified local entropy thresholding algorithm. In the second stage, different features are extracted including statistical moments and principal components. The set of extracted features is combined into one feature vector and fed into a Sequential Minimal Optimization (SMO) classifier. The obtained result is encouraging with an average accuracy of 68.33 %

Network-based features for retinal fundus vessel structure analysis

Retinal fundus imaging is a non-invasive method that allows visualizing the structure of the blood vessels in the retina whose features may indicate the presence of diseases such as diabetic retinopathy (DR) and glaucoma. Here we present a novel method to analyze and quantify changes in the retinal blood vessel structure in patients diagnosed with glaucoma or with DR. First, we use an automatic unsupervised segmentation algorithm to extract a tree-like graph from the retina blood vessel structure. The nodes of the graph represent branching (bifurcation) points and endpoints, while the links represent vessel segments that connect the nodes. Then, we quantify structural differences between the graphs extracted from the groups of healthy and non-healthy patients. We also use fractal analysis to characterize the extracted graphs. Applying these techniques to three retina fundus image databases we find significant differences between the healthy and non-healthy groups (p-values lower than 0.005 or 0.001 depending on the method and on the database). The results are sensitive to the segmentation method (manual or automatic) and to the resolution of the images.Peer ReviewedPostprint (published version