8 research outputs found

    Statistical analysis of ocean wave and wind parameters retrieved with an empirical SAR algorithum

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    A global dataset of two years (September 1998 to December 2000) of ERS SAR data was reprocessed to more than one million SAR imagettes. Met ocean Parameters like significant ocean wave height (H s), wind speed (U 10) and mean wave period (T m-10) are derived from the SAR images using a new empirical algorithm CWAVE [1]. The results are compared to collocated ERS altimeter data and in Situ measurements from NOAA buoys and observations taken onboard the vessel Polarstern. It is shown that the SAR derived H s is comparable in quality to altimeter measurements and can thus be used for real time assimilation

    Regulation and Function of Directly Repressed Targets of Wnt Signaling in Drosophila.

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    In multicellular organisms, cells communicate with each other through biochemical cascades known as signaling pathways. Being one of these pathways, Wnt signaling is repetitively used throughout animal development as well as in adult tissue regeneration and stem cell maintenance. Misregulation of Wnt signaling has been connected to several cancers, bone disease and metabolic disorders. While Wnt signaling has been studied for more than 30 years, many unanswered questions remain about how it influences cell fate and behavior. For instance, there has been considerable progress on understanding the basic mechanisms of how Wnt signaling regulates the transcription of its targets but how this pathway regulates different genes in distinct tissues/cell types is still poorly understood. My thesis work addressed the question of how Wnt signaling diversity is achieved by examining the Wnt-dependent regulation of Tiggrin (Tig), an essential Drosophila gene encoding an extracellular matrix protein. Unlike the vast majority of Wnt targets, which are activated by the pathway, Tig is directly repressed by Wnt stimulation. The first project of my thesis intended to better understand the mechanism of this repression. I discovered non-tranditional DNA motifs in a cis-regulatory module from the Tig locus that mediate Wnt-repression in the Drosophila hematopoietic system through bipartite recognition by TCF, the major transcription factor of the pathway. When swapped with the classic TCF binding sites, I found that the quality of TCF binding sites dictates the type of transcriptional output, i.e. activation or repression, likely through allosteric regulation of TCF. This work provides a paradigm for diversity in Wnt signaling and basic transcriptional regulation. The second project of my thesis describes the role of Tig in influencing hematopoiesis in Drosophila larva. I found that the Wee1 kinase, which slows G2/M progression, inhibits maturation of a major lineage of Drosophila immune cells through activation of Tig. This work elucidates connections between cell cycle regulators, the extracellular matrix and hematopoiesis.PHDMolecular, Cellular and Developmental BiologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/133313/1/chenzh_1.pd

    Current Air Quality Issues

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    Air pollution is thus far one of the key environmental issues in urban areas. Comprehensive air quality plans are required to manage air pollution for a particular area. Consequently, air should be continuously sampled, monitored, and modeled to examine different action plans. Reviews and research papers describe air pollution in five main contexts: Monitoring, Modeling, Risk Assessment, Health, and Indoor Air Pollution. The book is recommended to experts interested in health and air pollution issues

    Marine Aggregate Dredging: A New Regional Approach to Environmental Monitoring

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    The subject of this thesis is the marine aggregate dredging industry, and specifically the approach taken to the monitoring of environmental effects on the seabed. The thesis forms the evidence required to allow the author to be examined for a PhD by Publication, and comprises of a list of the author’s publications, a confirmation of the author’s contribution to the multi-authored papers, and a critical analysis of the published work. The critical analysis takes the form of an essay, in which a case for switching to a new system of environmental monitoring is outlined. The essay presents a logical development of ideas, starting with a description of the aggregates dredging industry. This is followed by a critical analysis of the author’s past research, with a particular emphasis on how the findings from this work are relevant to the issue of monitoring. This earlier work has addressed themes of: Impact (Cumulative Effects), The Relationship between Sediments and Benthos, Recovery, Restoration, Habitat Mapping and Natural Variability. The essay then describes the current approach to monitoring, together with its limitations. This is followed by a description of the new monitoring approach, with an explanation of why it is considered more suitable for meeting the needs of both the industry and the industry regulators. The essay considers what steps would need to be taken to implement the approach in the major dredging regions of the UK

    Performance Analysis For Wireless G (IEEE 802.11 G) And Wireless N (IEEE 802.11 N) In Outdoor Environment

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    This paper described an analysis the different capabilities and limitation of both IEEE technologies that has been utilized for data transmission directed to mobile device. In this work, we have compared an IEEE 802.11/g/n outdoor environment to know what technology is better. the comparison consider on coverage area (mobility), through put and measuring the interferences. The work presented here is to help the researchers to select the best technology depending of their deploying case, and investigate the best variant for outdoor. The tool used is Iperf software which is to measure the data transmission performance of IEEE 802.11n and IEEE 802.11g

    Performance analysis for wireless G (IEEE 802.11G) and wireless N (IEEE 802.11N) in outdoor environment

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    This paper described an analysis the different capabilities and limitation of both IEEE technologies that has been utilized for data transmission directed to mobile device. In this work, we have compared an IEEE 802.11/g/n outdoor environment to know what technology is better. The comparison consider on coverage area (mobility), throughput and measuring the interferences. The work presented here is to help the researchers to select the best technology depending of their deploying case, and investigate the best variant for outdoor. The tool used is Iperf software which is to measure the data transmission performance of IEEE 802.11n and IEEE 802.11g

    Validation of a new empirical SAR algorithum

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    A new empirical algorithm-CWAVE [1] was developed at the German Aerospace Center (DLR). A global dataset of two years (September 1998 to December 2000) of ERS SAR data was reprocessed to more than one million SAR imagettes. Met ocean Parameters like significant ocean wave height (H-s) wind speed (U-10) and mean wave period (Tm-10) are derived from the SAR images using the CWAVE algorithm [1]. The results are compared to collocated ERS altimeter data and in Situ measurements from NOAA buoys and observations taken onboard the vessel Polarstern. It is shown that the SAR derived H, is comparable in quality to altimeter measurements and can thus be used for real time assimilation
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