3,380 research outputs found

    White ants, empire and entomo-politics in South Asia

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    By focussing on the history of white ants in colonial South Asia, this article shows how insects were ubiquitous and fundamental to the shaping of British colonial power. British rule in India was vulnerable to white ants because these insects consumed paper and wood, the key material foundations of the colonial state. The white ant problem also made the colonial state more resilient and intrusive. The sphere of strict governmental intervention was extended to include both animate and inanimate nonhumans, while these insects were invoked as symbols to characterise colonised landscapes, peoples and cultures. Nonetheless, encounters with white ants were not entirely within the control of the colonial state. Despite effective state intervention, white ants didn’t vanish altogether, and remained objects of everyday control till the final decade of colonial rule and after. Meanwhile, colonised and post-colonial South Asians used white ants to articulate their own distinct political agendas. Over time, white ants featured variously as metaphors for Islamic decadence, British colonial exploitation, communism, democratic socialism and more recently, the Indian National Congress. This article argues that co-constitutive encounters between the worlds of insects and politics have been an intrinsic feature of British colonialism and its legacies in South Asia

    Efficient fast Fourier transform-based solvers for computing the thermomechanical behavior of applied materials

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    The mechanical behavior of many applied materials arises from their microstructure. Thus, to aid the design, development and industrialization of new materials, robust computational homogenization methods are indispensable. The present thesis is devoted to investigating and developing FFT-based micromechanics solvers for efficiently computing the (thermo)mechanical response of nonlinear composite materials with complex microstructures

    Opportunities and Challenges for the development of 'Core Outcome Sets' in Neuro-Oncology

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    Core Outcome Sets (COS) define minimum outcomes to be measured and reported in clinical effectiveness trials for a particular health condition/health area. Despite recognition as critical to clinical research design for other health areas, none have been developed for neuro-oncology. COS development projects should carefully consider: scope (how the COS should be used), stakeholders involved in development (including patients as both research partners and participants), and consensus methodologies used (typically a Delphi survey and consensus meeting), as well as dissemination plans. Developing COS for neuro-oncology is potentially challenging due to extensive tumor subclassification (including molecular stratification), different symptoms related to anatomical tumor location, and variation in treatment options. Development of a COS specific to tumor subtype, in a specific location, for a particular intervention may be too narrow and would be unlikely to be used. Equally, a COS that is applicable across a wider area of neuro-oncology may be too broad and therefore lack specificity. This review describes why and how a COS may be developed, and discusses challenges for their development, specific to neuro-oncology. The COS under development are briefly described, including: adult glioma, incidental/untreated meningioma, meningioma requiring intervention, and adverse events from surgical intervention for pediatric brain tumors. Keywords: clinical trial; core outcome set; effectiveness; glioma; meningioma

    Water Allocation Mechanisms: Principles and Examples

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    From the earliest times, water resources have been allocated on the basis of social criteria - maintaining the community by ensuring that water is available for human consumption, for sanitation, and for food production. Societies have invested capital in infrastructure to maintain this allocation. Yet social change, including changes in (and more understanding of) how goods are distributed, has produced new issues in water allocation. Population growth has made water scarcity a major problem in many countries and water pollution, while by no means a recent problem, is more widespread than ever before. Traditionally the state has played a dominant role in managing water resources, but inefficient use of water, poor cost recovery for operating and maintenance expenses, the mounting cost of developing new water sources, and problems with the quality of service in agency-managed systems has led to a search for alternatives that make water allocation and management more efficient. The authors address some of the basic principles of treating water as an economic good and of allocating it among the sectors. After outlining the economic principles behind allocating scarce water resources, they review the actual means of various mechanisms used for allocating water, including marginal cost pricing, social planning, user-based allocation, and water markets. Giving examples from experience in several countries, they weigh the pros and cons of different approaches to water allocation, showing that no single approach is suitable for all situations. Clearly that state must play an important regulatory role, for example, but how effectively it does so depends on the relative political influence of various stakeholders and segments of society. User-based allocation is generally more flexible than state allocation, but collective action is not equally effective everywhere; it is most likely to emerge where there is strong demand for water and a history of cooperation. The outcome of market allocation depends on the economic value of water for various uses, but moving toward tradable property rights in water may ease the process of intersectoral reallocation by compensating the"losers"and creating incentives for efficient water use in all sectors

    Reduced grid-like theta modulation in schizophrenia

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    The hippocampal formation has been implicated in the pathophysiology of schizophrenia, with patients showing impairments in spatial and relational cognition, structural changes in entorhinal cortex, and reduced theta coherence with medial prefrontal cortex. Both the entorhinal cortex and medial prefrontal cortex exhibit a six-fold (or 'hexadirectional') modulation of neural activity during virtual navigation that is indicative of grid cell populations and associated with accurate spatial navigation. Here, we examined whether these grid-like patterns are disrupted in schizophrenia. We asked 17 participants with diagnoses of schizophrenia and 23 controls (matched for age, sex and IQ) to perform a virtual reality spatial navigation task during magnetoencephalography. The control group showed stronger 4-10 Hz theta power during movement onset, as well as hexadirectional modulation of theta band oscillatory activity in the right entorhinal cortex whose directional stability across trials correlated with navigational accuracy. This hexadirectional modulation was absent in patients, with a significant difference between groups. These results suggest that impairments in spatial and relational cognition associated with schizophrenia may arise from disrupted grid firing patterns in entorhinal cortex

    Efficient fast Fourier transform-based solvers for computing the thermomechanical behavior of applied materials

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    The mechanical behavior of many applied materials arises from their microstructure. Thus, to aid the design, development and industrialization of new materials, robust computational homogenization methods are indispensable. The present thesis is devoted to investigating and developing FFT-based micromechanics solvers for efficiently computing the (thermo)mechanical response of nonlinear composite materials with complex microstructures
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