Advanced flight control system study

The architecture, requirements, and system elements of an ultrareliable, advanced flight control system are described. The basic criteria are functional reliability of 10 to the minus 10 power/hour of flight and only 6 month scheduled maintenance. A distributed system architecture is described, including a multiplexed communication system, reliable bus controller, the use of skewed sensor arrays, and actuator interfaces. Test bed and flight evaluation program are proposed

Verification, Analytical Validation, and Clinical Validation (V3): The Foundation of Determining Fit-for-Purpose for Biometric Monitoring Technologies (BioMeTs)

Digital medicine is an interdisciplinary field, drawing together stakeholders with expertize in engineering, manufacturing, clinical science, data science, biostatistics, regulatory science, ethics, patient advocacy, and healthcare policy, to name a few. Although this diversity is undoubtedly valuable, it can lead to confusion regarding terminology and best practices. There are many instances, as we detail in this paper, where a single term is used by different groups to mean different things, as well as cases where multiple terms are used to describe essentially the same concept. Our intent is to clarify core terminology and best practices for the evaluation of Biometric Monitoring Technologies (BioMeTs), without unnecessarily introducing new terms. We focus on the evaluation of BioMeTs as fit-for-purpose for use in clinical trials. However, our intent is for this framework to be instructional to all users of digital measurement tools, regardless of setting or intended use. We propose and describe a three-component framework intended to provide a foundational evaluation framework for BioMeTs. This framework includes (1) verification, (2) analytical validation, and (3) clinical validation. We aim for this common vocabulary to enable more effective communication and collaboration, generate a common and meaningful evidence base for BioMeTs, and improve the accessibility of the digital medicine field

A candidate architecture for monitoring and control in chemical transfer propulsion systems

To support the exploration of space, a reusable space-based rocket engine must be developed. This engine must sustain superior operability and man-rated levels of reliability over several missions with limited maintenance or inspection between flights. To meet these requirements, an expander cycle engine incorporating a highly capable control and health monitoring system is planned. Alternatives for the functional organization and the implementation architecture of the engine's monitoring and control system are discussed. On the basis of this discussion, a decentralized architecture is favored. The trade-offs between several implementation options are outlined and future work is proposed

Standardization of electroencephalography for multi-site, multi-platform and multi-investigator studies: Insights from the canadian biomarker integration network in depression

Subsequent to global initiatives in mapping the human brain and investigations of neurobiological markers for brain disorders, the number of multi-site studies involving the collection and sharing of large volumes of brain data, including electroencephalography (EEG), has been increasing. Among the complexities of conducting multi-site studies and increasing the shelf life of biological data beyond the original study are timely standardization and documentation of relevant study parameters. We presentthe insights gained and guidelines established within the EEG working group of the Canadian Biomarker Integration Network in Depression (CAN-BIND). CAN-BIND is a multi-site, multi-investigator, and multiproject network supported by the Ontario Brain Institute with access to Brain-CODE, an informatics platform that hosts a multitude of biological data across a growing list of brain pathologies. We describe our approaches and insights on documenting and standardizing parameters across the study design, data collection, monitoring, analysis, integration, knowledge-translation, and data archiving phases of CAN-BIND projects. We introduce a custom-built EEG toolbox to track data preprocessing with open-access for the scientific community. We also evaluate the impact of variation in equipment setup on the accuracy of acquired data. Collectively, this work is intended to inspire establishing comprehensive and standardized guidelines for multi-site studies

Methods for Performance Evaluation of Parallel Computer Systems

Although parallel computers have existed for many years, recently there has been a surge of academic, industrial and governmental interest in parallel computing. Commercially manufactured parallel computers have started to become available. Many new experimental parallel architectures are reported in the literature every year. Software for many types of applications, from scientific number crunching to artificial intelligence, is being written to run on parallel machines. Performance is an essential consideration both in the design of new systems and the deployment of existing systems. Users of computers wish to utilize their hardware and software systems as efficiently as possible. Over the years, a field known as computer performance evaluation has arisen to address the problem of quantifying and predicting computer performance. Methods exist that can determine how efficiently a system's resources are being used. These can help track down the probable causes of performance problems

Run Time Approximation of Non-blocking Service Rates for Streaming Systems

Stream processing is a compute paradigm that promises safe and efficient parallelism. Modern big-data problems are often well suited for stream processing's throughput-oriented nature. Realization of efficient stream processing requires monitoring and optimization of multiple communications links. Most techniques to optimize these links use queueing network models or network flow models, which require some idea of the actual execution rate of each independent compute kernel within the system. What we want to know is how fast can each kernel process data independent of other communicating kernels. This is known as the "service rate" of the kernel within the queueing literature. Current approaches to divining service rates are static. Modern workloads, however, are often dynamic. Shared cloud systems also present applications with highly dynamic execution environments (multiple users, hardware migration, etc.). It is therefore desirable to continuously re-tune an application during run time (online) in response to changing conditions. Our approach enables online service rate monitoring under most conditions, obviating the need for reliance on steady state predictions for what are probably non-steady state phenomena. First, some of the difficulties associated with online service rate determination are examined. Second, the algorithm to approximate the online non-blocking service rate is described. Lastly, the algorithm is implemented within the open source RaftLib framework for validation using a simple microbenchmark as well as two full streaming applications.Comment: technical repor

PERFORMANCE EVALUATION ON QUALITY OF ASIAN AIRLINES WEBSITES – AN AHP PPROACH

In recent years, many people have devoted their efforts to the issue of quality of Web site. The concept of quality is consisting of many criteria: quality of service perspective, a user perspective, a content perspective or indeed a usability perspective. Because of its possible instant worldwide audience a Website’s quality and reliability are crucial. The very special nature of the web applications and websites pose unique software testing challenges. Webmasters, Web applications developers, and Website quality assurance managers need tools and methods that can match up to the new needs. This research conducts some tests to measure the quality web site of Asian flag carrier airlines via web diagnostic tools online. We propose a methodology for determining and evaluate the best airlines websites based on many criteria of website quality. The approach has been implemented using Analytical Hierarchy Process (AHP) to generate the weights for the criteria which are much better and guarantee more fairly preference of criteria. The proposed model uses the AHP pairwise comparisons and the measure scale to generate the weights for the criteria which are much better and guarantee more fairly preference of criteria. The result of this study confirmed that the airlines websites of Asian are neglecting performance and quality criteria

Using latent-semantic analysis and network analysis for monitoring conceptual development

This paper describes and evaluates CONSPECT (from concept inspection), an application that analyses states in a learner’s conceptual development. It was designed to help online learners and their tutors monitor conceptual development and also to help reduce the workload of tutors monitoring a learner’s conceptual development. CONSPECT combines two technologies - Latent Semantic Analysis (LSA) and Network Analysis (NA) into a technique called Meaningful Interaction Analysis (MIA). LSA analyses the meaning in the textual digital traces left behind by learners in their learning journey; NA provides the analytic instrument to investigate (visually) the semantic structures identified by LSA. This paper describes the validation activities undertaken to show how well LSA matches first year medical students in 1) grouping similar concepts and 2) annotating text