Low-Voltage Bulk-Driven Amplifier Design and Its Application in Implantable Biomedical Sensors

The powering unit usually represents a significant component of the implantable biomedical sensor system since the integrated circuits (ICs) inside for monitoring different physiological functions consume a great amount of power. One method to reduce the volume of the powering unit is to minimize the power supply voltage of the entire system. On the other hand, with the development of the deep sub-micron CMOS technologies, the minimum channel length for a single transistor has been scaled down aggressively which facilitates the reduction of the chip area as well. Unfortunately, as an inevitable part of analytic systems, analog circuits such as the potentiostat are not amenable to either low-voltage operations or short channel transistor scheme. To date, several proposed low-voltage design techniques have not been adopted by mainstream analog circuits for reasons such as insufficient transconductance, limited dynamic range, etc. Operational amplifiers (OpAmps) are the most fundamental circuit blocks among all analog circuits. They are also employed extensively inside the implantable biosensor systems. This work first aims to develop a general purpose high performance low-voltage low-power OpAmp. The proposed OpAmp adopts the bulk-driven low-voltage design technique. An innovative low-voltage bulk-driven amplifier with enhanced effective transconductance is developed in an n-well digital CMOS process operating under 1-V power supply. The proposed circuit employs auxiliary bulk-driven input differential pairs to achieve the input transconductance comparable with the traditional gate-driven amplifiers, without consuming a large amount of current. The prototype measurement results show significant improvements in the open loop gain (AO) and the unity-gain bandwidth (UGBW) compared to other works. A 1-V potentiostat circuit for an implantable electrochemical sensor is then proposed by employing this bulk-driven amplifier. To the best of the author’s knowledge, this circuit represents the first reported low-voltage potentiostat system. This 1-V potentiostat possesses high linearity which is comparable or even better than the conventional potentiostat designs thanks to this transconductance enhanced bulk-driven amplifier. The current consumption of the overall potentiostat is maintained around 22 microampere. The area for the core layout of the integrated circuit chip is 0.13 mm2 for a 0.35 micrometer process

Exploiting the bulk-driven approach in CMOS analogue amplifier design

This thesis presents a collection of new novel techniques using the bulk-driven approach, which can lead to performance enhancement in the field of CMOS analogue amplifier design under the very low-supply voltage constraints. In this thesis, three application areas of the bulk-driven approach are focused – at the input-stage of differential pairs, at the source followers, and at the cascode devices. For the input stage of differential pairs, this thesis proposes two new novel circuit design techniques. One of them utilises the concept of the replica-biased scheme in order to solve the non-linearity and latch-up issues, which are the potential problems that come along with the bulk-driven approach. The other proposed circuit design technique utilises the flipped voltage scheme and the Quasi-Floating Gate technique in order to achieve low-power high-speed performances, and furthermore the reversed-biased diode concept to overcome the issue of degraded input impedance characteristics that come along with the bulk-driven approach. Applying the bulk-driven approach in source followers is a new type of circuit blocks in CMOS analogue field, in which to the author’s best knowledge has not been proposed at any literatures in the past. This thesis presents the bulk-driven version of the flipped voltage followers and super source followers, which can lead to eliminating the DC level shift. Furthermore, a technique for programming the DC level shift less than the threshold voltage of a MOSFET, which cannot be achieved by conventional types of source followers, is presented. The effectiveness of the cascode device using the bulk-driven approach is validated by implementing it in a complete schematics design of a fully differential bulk-driven operational transcoductance amplifier (OTA). This proposal leads to solving the lowtranconductance problem of a bulk-driven differential pair, and in effect the open loop gain of the OTA exceeds 60dB using a 0.35μm CMOS technology. The final part of this thesis provides the study result of the input capacitance of a bulk-driven buffer. To verify the use of the BSIM3 MOSFET model in the simulation for predicting the input capacitance, the measurement data of the fabricated device are compared with the postlayout simulation results

Exploiting the bulk-driven approach in CMOS analogue amplifier design

This thesis presents a collection of new novel techniques using the bulk-driven approach, which can lead to performance enhancement in the field of CMOS analogue amplifier design under the very low-supply voltage constraints. In this thesis, three application areas of the bulk-driven approach are focused – at the input-stage of differential pairs, at the source followers, and at the cascode devices. For the input stage of differential pairs, this thesis proposes two new novel circuit design techniques. One of them utilises the concept of the replica-biased scheme in order to solve the non-linearity and latch-up issues, which are the potential problems that come along with the bulk-driven approach. The other proposed circuit design technique utilises the flipped voltage scheme and the Quasi-Floating Gate technique in order to achieve low-power high-speed performances, and furthermore the reversed-biased diode concept to overcome the issue of degraded input impedance characteristics that come along with the bulk-driven approach. Applying the bulk-driven approach in source followers is a new type of circuit blocks in CMOS analogue field, in which to the author’s best knowledge has not been proposed at any literatures in the past. This thesis presents the bulk-driven version of the flipped voltage followers and super source followers, which can lead to eliminating the DC level shift. Furthermore, a technique for programming the DC level shift less than the threshold voltage of a MOSFET, which cannot be achieved by conventional types of source followers, is presented. The effectiveness of the cascode device using the bulk-driven approach is validated by implementing it in a complete schematics design of a fully differential bulk-driven operational transcoductance amplifier (OTA). This proposal leads to solving the lowtranconductance problem of a bulk-driven differential pair, and in effect the open loop gain of the OTA exceeds 60dB using a 0.35μm CMOS technology. The final part of this thesis provides the study result of the input capacitance of a bulk-driven buffer. To verify the use of the BSIM3 MOSFET model in the simulation for predicting the input capacitance, the measurement data of the fabricated device are compared with the postlayout simulation results