6,794 research outputs found
Self-adaptive exploration in evolutionary search
We address a primary question of computational as well as biological research
on evolution: How can an exploration strategy adapt in such a way as to exploit
the information gained about the problem at hand? We first introduce an
integrated formalism of evolutionary search which provides a unified view on
different specific approaches. On this basis we discuss the implications of
indirect modeling (via a ``genotype-phenotype mapping'') on the exploration
strategy. Notions such as modularity, pleiotropy and functional phenotypic
complex are discussed as implications. Then, rigorously reflecting the notion
of self-adaptability, we introduce a new definition that captures
self-adaptability of exploration: different genotypes that map to the same
phenotype may represent (also topologically) different exploration strategies;
self-adaptability requires a variation of exploration strategies along such a
``neutral space''. By this definition, the concept of neutrality becomes a
central concern of this paper. Finally, we present examples of these concepts:
For a specific grammar-type encoding, we observe a large variability of
exploration strategies for a fixed phenotype, and a self-adaptive drift towards
short representations with highly structured exploration strategy that matches
the ``problem's structure''.Comment: 24 pages, 5 figure
KInNeSS: A Modular Framework for Computational Neuroscience
Making use of very detailed neurophysiological, anatomical, and behavioral data to build biological-realistic computational models of animal behavior is often a difficult task. Until recently, many software packages have tried to resolve this mismatched granularity with different approaches. This paper presents KInNeSS, the KDE Integrated NeuroSimulation Software environment, as an alternative solution to bridge the gap between data and model behavior. This open source neural simulation software package provides an expandable framework incorporating features such as ease of use, scalabiltiy, an XML based schema, and multiple levels of granularity within a modern object oriented programming design. KInNeSS is best suited to simulate networks of hundreds to thousands of branched multu-compartmental neurons with biophysical properties such as membrane potential, voltage-gated and ligand-gated channels, the presence of gap junctions of ionic diffusion, neuromodulation channel gating, the mechanism for habituative or depressive synapses, axonal delays, and synaptic plasticity. KInNeSS outputs include compartment membrane voltage, spikes, local-field potentials, and current source densities, as well as visualization of the behavior of a simulated agent. An explanation of the modeling philosophy and plug-in development is also presented. Further developement of KInNeSS is ongoing with the ultimate goal of creating a modular framework that will help researchers across different disciplines to effecitively collaborate using a modern neural simulation platform.Center for Excellence for Learning Education, Science, and Technology (SBE-0354378); Air Force Office of Scientific Research (F49620-01-1-0397); Office of Naval Research (N00014-01-1-0624
The Pivotal Role of Causality in Local Quantum Physics
In this article an attempt is made to present very recent conceptual and
computational developments in QFT as new manifestations of old and well
establihed physical principles. The vehicle for converting the
quantum-algebraic aspects of local quantum physics into more classical
geometric structures is the modular theory of Tomita. As the above named
laureate to whom I have dedicated has shown together with his collaborator for
the first time in sufficient generality, its use in physics goes through
Einstein causality. This line of research recently gained momentum when it was
realized that it is not only of structural and conceptual innovative power (see
section 4), but also promises to be a new computational road into
nonperturbative QFT (section 5) which, picturesquely speaking, enters the
subject on the extreme opposite (noncommutative) side.Comment: This is a updated version which has been submitted to Journal of
Physics A, tcilatex 62 pages. Adress: Institut fuer Theoretische Physik
FU-Berlin, Arnimallee 14, 14195 Berlin presently CBPF, Rua Dr. Xavier Sigaud
150, 22290-180 Rio de Janeiro, Brazi
A morphospace of functional configuration to assess configural breadth based on brain functional networks
The best approach to quantify human brain functional reconfigurations in
response to varying cognitive demands remains an unresolved topic in network
neuroscience. We propose that such functional reconfigurations may be
categorized into three different types: i) Network Configural Breadth, ii)
Task-to-Task transitional reconfiguration, and iii) Within-Task
reconfiguration. In order to quantify these reconfigurations, we propose a
mesoscopic framework focused on functional networks (FNs) or communities. To do
so, we introduce a 2D network morphospace that relies on two novel mesoscopic
metrics, Trapping Efficiency (TE) and Exit Entropy (EE), which capture topology
and integration of information within and between a reference set of FNs. In
this study, we use this framework to quantify the Network Configural Breadth
across different tasks. We show that the metrics defining this morphospace can
differentiate FNs, cognitive tasks and subjects. We also show that network
configural breadth significantly predicts behavioral measures, such as episodic
memory, verbal episodic memory, fluid intelligence and general intelligence. In
essence, we put forth a framework to explore the cognitive space in a
comprehensive manner, for each individual separately, and at different levels
of granularity. This tool that can also quantify the FN reconfigurations that
result from the brain switching between mental states.Comment: main article: 24 pages, 8 figures, 2 tables. supporting information:
11 pages, 5 figure
Optimal map of the modular structure of complex networks
Modular structure is pervasive in many complex networks of interactions
observed in natural, social and technological sciences. Its study sheds light
on the relation between the structure and function of complex systems.
Generally speaking, modules are islands of highly connected nodes separated by
a relatively small number of links. Every module can have contributions of
links from any node in the network. The challenge is to disentangle these
contributions to understand how the modular structure is built. The main
problem is that the analysis of a certain partition into modules involves, in
principle, as many data as number of modules times number of nodes. To confront
this challenge, here we first define the contribution matrix, the mathematical
object containing all the information about the partition of interest, and
after, we use a Truncated Singular Value Decomposition to extract the best
representation of this matrix in a plane. The analysis of this projection allow
us to scrutinize the skeleton of the modular structure, revealing the structure
of individual modules and their interrelations.Comment: 21 pages, 10 figure
Motivations and Physical Aims of Algebraic QFT
We present illustrations which show the usefulness of algebraic QFT. In
particular in low-dimensional QFT, when Lagrangian quantization does not exist
or is useless (e.g. in chiral conformal theories), the algebraic method is
beginning to reveal its strength.Comment: 40 pages of LateX, additional remarks resulting from conversations
and mail contents, removal of typographical error
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