74,982 research outputs found
Topological Feature Based Classification
There has been a lot of interest in developing algorithms to extract clusters
or communities from networks. This work proposes a method, based on
blockmodelling, for leveraging communities and other topological features for
use in a predictive classification task. Motivated by the issues faced by the
field of community detection and inspired by recent advances in Bayesian topic
modelling, the presented model automatically discovers topological features
relevant to a given classification task. In this way, rather than attempting to
identify some universal best set of clusters for an undefined goal, the aim is
to find the best set of clusters for a particular purpose.
Using this method, topological features can be validated and assessed within
a given context by their predictive performance.
The proposed model differs from other relational and semi-supervised learning
models as it identifies topological features to explain the classification
decision. In a demonstration on a number of real networks the predictive
capability of the topological features are shown to rival the performance of
content based relational learners. Additionally, the model is shown to
outperform graph-based semi-supervised methods on directed and approximately
bipartite networks.Comment: Awarded 3rd Best Student Paper at 14th International Conference on
Information Fusion 201
Topological singularities and the general classification of Floquet-Bloch systems
Recent works have demonstrated that the Floquet-Bloch bands of
periodically-driven systems feature a richer topological structure than their
non-driven counterparts. The additional structure in the driven case arises
from the periodicity of quasienergy, the energy-like quantity that defines the
spectrum of a periodically-driven system. Here we develop a new paradigm for
the topological classification of Floquet-Bloch bands, based on the
time-dependent spectrum of the driven system's evolution operator throughout
one driving period. Specifically, we show that this spectrum may host
topologically-protected degeneracies at intermediate times, which control the
topology of the Floquet bands of the full driving cycle. This approach provides
a natural framework for incorporating the role of symmetries, enabling a
unified and complete classification of Floquet-Bloch bands and yielding new
insight into the topological features that distinguish driven and non-driven
systems.Comment: 19 pages, 6 figure
Topological classifier for detecting the emergence of epileptic seizures
Objective
An innovative method based on topological data analysis is introduced for classifying EEG recordings of patients affected by epilepsy. We construct a topological space from a collection of EEGs signals using Persistent Homology; then, we analyse the space by Persistent entropy, a global topological feature, in order to classify healthy and epileptic signals.
Results
The performance of the resulting one-feature-based linear topological classifier is tested by analysing the Physionet dataset. The quality of classification is evaluated in terms of the Area Under Curve (AUC) of the receiver operating characteristic curve. It is shown that the linear topological classifier has an AUC equal to 97.2% while the performance of a classifier based on Sample Entropy has an AUC equal to 62.0%
A topological approach for protein classification
Protein function and dynamics are closely related to its sequence and
structure. However prediction of protein function and dynamics from its
sequence and structure is still a fundamental challenge in molecular biology.
Protein classification, which is typically done through measuring the
similarity be- tween proteins based on protein sequence or physical
information, serves as a crucial step toward the understanding of protein
function and dynamics. Persistent homology is a new branch of algebraic
topology that has found its success in the topological data analysis in a
variety of disciplines, including molecular biology. The present work explores
the potential of using persistent homology as an indepen- dent tool for protein
classification. To this end, we propose a molecular topological fingerprint
based support vector machine (MTF-SVM) classifier. Specifically, we construct
machine learning feature vectors solely from protein topological fingerprints,
which are topological invariants generated during the filtration process. To
validate the present MTF-SVM approach, we consider four types of problems.
First, we study protein-drug binding by using the M2 channel protein of
influenza A virus. We achieve 96% accuracy in discriminating drug bound and
unbound M2 channels. Additionally, we examine the use of MTF-SVM for the
classification of hemoglobin molecules in their relaxed and taut forms and
obtain about 80% accuracy. The identification of all alpha, all beta, and
alpha-beta protein domains is carried out in our next study using 900 proteins.
We have found a 85% success in this identifica- tion. Finally, we apply the
present technique to 55 classification tasks of protein superfamilies over 1357
samples. An average accuracy of 82% is attained. The present study establishes
computational topology as an independent and effective alternative for protein
classification
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