Feature Extraction and Classification of Automatically Segmented Lung Lesion Using Improved Toboggan Algorithm

The accurate detection of lung lesions from computed tomography (CT) scans is essential for clinical diagnosis. It provides valuable information for treatment of lung cancer. However, the process is exigent to achieve a fully automatic lesion detection. Here, a novel segmentation algorithm is proposed, it's an improved toboggan algorithm with a three-step framework, which includes automatic seed point selection, multi-constraints lesion extraction and the lesion refinement. Then, the features like local binary pattern (LBP), wavelet, contourlet, grey level co-occurence matrix (GLCM) are applied to each region of interest of the segmented lung lesion image to extract the texture features such as contrast, homogeneity, energy, entropy and statistical extraction like mean, variance, standard deviation, convolution of modulated and normal frequencies. Finally, support vector machine (SVM) and K-nearest neighbour (KNN) classifiers are applied to classify the abnormal region based on the performance of the extracted features and their performance is been compared. The accuracy of 97.8% is been obtained by using SVM classifier when compared to KNN classifier. This approach does not require any human interaction for lesion detection. Thus, the improved toboggan algorithm can achieve precise lung lesion segmentation in CT images. The features extracted also helps to classify the lesion region of lungs efficiently

GBM Volumetry using the 3D Slicer Medical Image Computing Platform

Volumetric change in glioblastoma multiforme (GBM) over time is a critical factor in treatment decisions. Typically, the tumor volume is computed on a slice-by-slice basis using MRI scans obtained at regular intervals. (3D)Slicer – a free platform for biomedical research – provides an alternative to this manual slice-by-slice segmentation process, which is significantly faster and requires less user interaction. In this study, 4 physicians segmented GBMs in 10 patients, once using the competitive region-growing based GrowCut segmentation module of Slicer, and once purely by drawing boundaries completely manually on a slice-by-slice basis. Furthermore, we provide a variability analysis for three physicians for 12 GBMs. The time required for GrowCut segmentation was on an average 61% of the time required for a pure manual segmentation. A comparison of Slicer-based segmentation with manual slice-by-slice segmentation resulted in a Dice Similarity Coefficient of 88.43 ± 5.23% and a Hausdorff Distance of 2.32 ± 5.23 mm

Analyses of the Watershed Transform

International audienceIn the framework of mathematical morphology, watershed transform (WT) represents a key step in image segmentation procedure. In this paper, we present a thorough analysis of some existing watershed approaches in the discrete case: WT based on flooding, WT based on path-cost minimization, watershed based on topology preservation, WT based on local condition and WT based on minimum spanning forest. For each approach, we present detailed description of processing procedure followed by mathematical foundations and algorithm of reference. Recent publications based on some approaches are also presented and discussed. Our study concludes with a classification of different watershed transform algorithms according to solution uniqueness, topology preservation, prerequisites minima computing and linearity

Methods for Real-time Visualization and Interaction with Landforms

This thesis presents methods to enrich data modeling and analysis in the geoscience domain with a particular focus on geomorphological applications. First, a short overview of the relevant characteristics of the used remote sensing data and basics of its processing and visualization are provided. Then, two new methods for the visualization of vector-based maps on digital elevation models (DEMs) are presented. The first method uses a texture-based approach that generates a texture from the input maps at runtime taking into account the current viewpoint. In contrast to that, the second method utilizes the stencil buffer to create a mask in image space that is then used to render the map on top of the DEM. A particular challenge in this context is posed by the view-dependent level-of-detail representation of the terrain geometry. After suitable visualization methods for vector-based maps have been investigated, two landform mapping tools for the interactive generation of such maps are presented. The user can carry out the mapping directly on the textured digital elevation model and thus benefit from the 3D visualization of the relief. Additionally, semi-automatic image segmentation techniques are applied in order to reduce the amount of user interaction required and thus make the mapping process more efficient and convenient. The challenge in the adaption of the methods lies in the transfer of the algorithms to the quadtree representation of the data and in the application of out-of-core and hierarchical methods to ensure interactive performance. Although high-resolution remote sensing data are often available today, their effective resolution at steep slopes is rather low due to the oblique acquisition angle. For this reason, remote sensing data are suitable to only a limited extent for visualization as well as landform mapping purposes. To provide an easy way to supply additional imagery, an algorithm for registering uncalibrated photos to a textured digital elevation model is presented. A particular challenge in registering the images is posed by large variations in the photos concerning resolution, lighting conditions, seasonal changes, etc. The registered photos can be used to increase the visual quality of the textured DEM, in particular at steep slopes. To this end, a method is presented that combines several georegistered photos to textures for the DEM. The difficulty in this compositing process is to create a consistent appearance and avoid visible seams between the photos. In addition to that, the photos also provide valuable means to improve landform mapping. To this end, an extension of the landform mapping methods is presented that allows the utilization of the registered photos during mapping. This way, a detailed and exact mapping becomes feasible even at steep slopes