Getting the best outcomes from epilepsy surgery.

Neurosurgery is an underutilized treatment that can potentially cure drug-refractory epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to ensure optimal outcomes. Advances in neuroimaging have improved diagnosis and guided surgical intervention. Invasive electroencephalography allows the evaluation of complex patients who would otherwise not be candidates for neurosurgery. We review the current state of the assessment and selection of patients and consider established and novel surgical procedures and associated outcome data. We aim to dispel myths that may inhibit physicians from referring and patients from considering neurosurgical intervention for drug-refractory focal epilepsies. Ann Neurol 2018;83:676-690

Proximity and gaze influences facial temperature:a thermal infrared imaging study

Direct gaze and interpersonal proximity are known to lead to changes in psycho-physiology, behaviour and brain function. We know little, however, about subtler facial reactions such as rise and fall in temperature, which may be sensitive to contextual effects and functional in social interactions. Using thermal infrared imaging cameras 18 female adult participants were filmed at two interpersonal distances (intimate and social) and two gaze conditions (averted and direct). The order of variation in distance was counterbalanced: half the participants experienced a female experimenter’s gaze at the social distance first before the intimate distance (a socially ‘normal’ order) and half experienced the intimate distance first and then the social distance (an odd social order). At both distances averted gaze always preceded direct gaze. We found strong correlations in thermal changes between six areas of the face (forehead, chin, cheeks, nose, maxilliary and periorbital regions) for all experimental conditions and developed a composite measure of thermal shifts for all analyses. Interpersonal proximity led to a thermal rise, but only in the ‘normal’ social order. Direct gaze, compared to averted gaze, led to a thermal increase at both distances with a stronger effect at intimate distance, in both orders of distance variation. Participants reported direct gaze as more intrusive than averted gaze, especially at the intimate distance. These results demonstrate the powerful effects of another person’s gaze on psycho-physiological responses, even at a distance and independent of context

Polar Fusion Technique Analysis for Evaluating the Performances of Image Fusion of Thermal and Visual Images for Human Face Recognition

This paper presents a comparative study of two different methods, which are based on fusion and polar transformation of visual and thermal images. Here, investigation is done to handle the challenges of face recognition, which include pose variations, changes in facial expression, partial occlusions, variations in illumination, rotation through different angles, change in scale etc. To overcome these obstacles we have implemented and thoroughly examined two different fusion techniques through rigorous experimentation. In the first method log-polar transformation is applied to the fused images obtained after fusion of visual and thermal images whereas in second method fusion is applied on log-polar transformed individual visual and thermal images. After this step, which is thus obtained in one form or another, Principal Component Analysis (PCA) is applied to reduce dimension of the fused images. Log-polar transformed images are capable of handling complicacies introduced by scaling and rotation. The main objective of employing fusion is to produce a fused image that provides more detailed and reliable information, which is capable to overcome the drawbacks present in the individual visual and thermal face images. Finally, those reduced fused images are classified using a multilayer perceptron neural network. The database used for the experiments conducted here is Object Tracking and Classification Beyond Visible Spectrum (OTCBVS) database benchmark thermal and visual face images. The second method has shown better performance, which is 95.71% (maximum) and on an average 93.81% as correct recognition rate.Comment: Proceedings of IEEE Workshop on Computational Intelligence in Biometrics and Identity Management (IEEE CIBIM 2011), Paris, France, April 11 - 15, 201

Increase in environmental temperature affects exploratory behaviour, anxiety and social preference in Danio rerio

The aim of this work is to investigate the effect of a temperature increase on the behaviour of adult zebrafish (Danio rerio) maintained for 21 days at 34 °C (treatment) and 26 °C (control). The temperatures chosen are within the vital range of zebrafish and correspond to temperatures that this species encounters in the natural environment. Previous results showed that the same treatment affects the brain proteome and the behaviour of adult zebrafish by producing alterations in the proteins involved in neurotransmitter release and synaptic function and impairing fish exploratory behaviour. In this study, we have investigated the performance of treated and control zebrafish during environmental exploration by using four behavioural tests (novel tank diving, light and dark preference, social preference and mirror biting) that are paradigms for assessing the state of anxiety, boldness, social preference and aggressive behaviour, respectively. The results showed that heat treatment reduces anxiety and increases the boldness of zebrafish, which spent more time in potentially dangerous areas of the tank such as the top and the uncovered bright area and at a distance from the social group, thus decreasing protection for the zebrafish. These data suggest that the increase in ambient temperature may compromise zebrafish survival rate in the natural environment

Identification of suitable biomarkers for stress and emotion detection for future personal affective wearable sensors

Skin conductivity (i.e., sweat) forms the basis of many physiology-based emotion and stress detection systems. However, such systems typically do not detect the biomarkers present in sweat, and thus do not take advantage of the biological information in the sweat. Likewise, such systems do not detect the volatile organic components (VOC’s) created under stressful conditions. This work presents a review into the current status of human emotional stress biomarkers and proposes the major potential biomarkers for future wearable sensors in affective systems. Emotional stress has been classified as a major contributor in several social problems, related to crime, health, the economy, and indeed quality of life. While blood cortisol tests, electroencephalography and physiological parameter methods are the gold standards for measuring stress; however, they are typically invasive or inconvenient and not suitable for wearable real-time stress monitoring. Alternatively, cortisol in biofluids and VOCs emitted from the skin appear to be practical and useful markers for sensors to detect emotional stress events. This work has identified antistress hormones and cortisol metabolites as the primary stress biomarkers that can be used in future sensors for wearable affective systems

Aerospace medicine and biology: A continuing bibliography with indexes (supplement 323)

This bibliography lists 125 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during April, 1989. Subject coverage includes; aerospace medicine and psychology, life support systems and controlled environments, safety equipment exobiology and extraterrestrial life, and flight crew behavior and performance

Remote sensing of strong emotions using electro-optical imaging technique

©Cranfield UniversityThis thesis reports a summary of the PhD programme for the assessment of person‘s emotional anxiety using Electro-optical technology. The thesis focuses mainly on the understanding of fundamental properties of physiological responses to emotional anxiety and how they can be captured by using Electro-optical (EO) imaging methods such as hyperspectral imaging (HSI) and thermal imaging (TI) techniques. The thesis summarises three main areas of work that have been undertaken by the author in the programme: (a) Experimental set up including HSI system and data acquisition software design and implementation, (b) fundamental understanding of physiological responses to emotional anxiety from the EO perspective and (c) the development of a novel remote sensing technique for the assessment of emotions without the requirement of base line information. One of our main results is to provide evidence to prove that the mean temperature in the periorbital region remains the same within 0.2°C during emotional anxiety. Furthermore, we have shown that it is the high temperature pixels within the periorbital, which increases in numbers by a huge amount after 2 minutes of the onset of anxiety. We have also developed techniques to allow the assessment anxiety without the need of base line information. The method has been tested using a sample size of about 40 subjects, and achieved promising result. Technologies for the remote sensing of heart beat rate has been in great demand, this study also involves the development of heart beat detection using TI system. Moreover, we have also attempted for the first time to sense glucose concentration from the blood sample in-vivo using HSI technique remotely

An Empirical Study Comparing Unobtrusive Physiological Sensors for Stress Detection in Computer Work.

Several unobtrusive sensors have been tested in studies to capture physiological reactions to stress in workplace settings. Lab studies tend to focus on assessing sensors during a specific computer task, while in situ studies tend to offer a generalized view of sensors' efficacy for workplace stress monitoring, without discriminating different tasks. Given the variation in workplace computer activities, this study investigates the efficacy of unobtrusive sensors for stress measurement across a variety of tasks. We present a comparison of five physiological measurements obtained in a lab experiment, where participants completed six different computer tasks, while we measured their stress levels using a chest-band (ECG, respiration), a wristband (PPG and EDA), and an emerging thermal imaging method (perinasal perspiration). We found that thermal imaging can detect increased stress for most participants across all tasks, while wrist and chest sensors were less generalizable across tasks and participants. We summarize the costs and benefits of each sensor stream, and show how some computer use scenarios present usability and reliability challenges for stress monitoring with certain physiological sensors. We provide recommendations for researchers and system builders for measuring stress with physiological sensors during workplace computer use