XML in Motion from Genome to Drug

Information technology (IT) has emerged as a central to the solution of contemporary genomics and drug discovery problems. Researchers involved in genomics, proteomics, transcriptional profiling, high throughput structure determination, and in other sub-disciplines of bioinformatics have direct impact on this IT revolution. As the full genome sequences of many species, data from structural genomics, micro-arrays, and proteomics became available, integration of these data to a common platform require sophisticated bioinformatics tools. Organizing these data into knowledgeable databases and developing appropriate software tools for analyzing the same are going to be major challenges. XML (eXtensible Markup Language) forms the backbone of biological data representation and exchange over the internet, enabling researchers to aggregate data from various heterogeneous data resources. The present article covers a comprehensive idea of the integration of XML on particular type of biological databases mainly dealing with sequence-structure-function relationship and its application towards drug discovery. This e-medical science approach should be applied to other scientific domains and the latest trend in semantic web applications is also highlighted

USING WEB TECHNOLOGY TO IMPROVE THE ACCOUNTING OF SMALL AND MEDIUM ENTERPRISES. AN ACADEMIC APPROACH TO IMPLEMENTATION OF IFRS

One way of supporting the accounting standard-setting process and to facilitatethe access to those standards is through the implementation of modern accounting reportingmethods using web technology. In this regard SMEs are under stress of two major factors:implementation of accounting standards and revolution in IT technology. The purpose of thispaper is to define the web accounting, explain the implications of web accounting for IFRSand discuss the key features in implementing this form of accounting for Small and MediumEnterprises(SME‘s). Web accounting is accounting software based on XML technology thatstores records and processes accounting transactions using HTTP as its primarycommunications protocol, and delivers web based information in HTML format and thentranslated in other formats. Web based accounting, will provide the benefit of cost savingsand increasing efficiency. It also will allows employees and external users (suppliers,customers and investors) a real time access to accounting data, translating reports in XBRLformat and facilitate adoption of IFRS.Web Accounting, SMEs, Web Technology, XML, XBRL, IFRS

What is a ‘musical work’? Reflections on the origins of the ‘work concept’ in western art music

No abstract available

The Road to Rebellion

In this essay, Dr. Erik J. Chaput and Russell DeSimone examine and contextualize the events surrounding the Dorr Rebellion of 1842 and the consequences that followed for those involved, primarily Providence attorney Thomas Wilson Dorr, who was the figurehead of one of the most significant constitutional reform efforts in antebellum American history. This essay, along with a collection of letters it accompanies on our Dorr Rebellion Letters project site, examines the momentous importance of the rebellion in terms of local Rhode Island history and national constitutional reform. The Dorr Rebellion Project http://library.providence.edu/dorr The Dorr Letters Project http://library.providence.edu:8080/xtf/index.htm

Nationalism, Myth and Reinterpretation of History: The Neglected Case of Interwar Yugoslavia

This article discusses and challenges some popular myths and perceptions about interwar Yugoslavia in post-socialist (and post-Yugoslav) Serbia. These include discourses that blame ‘others’ – ‘treacherous’ Croats and other non-Serbs, the ‘perfidious’ west, especially Britain – and that are also self-critical, of Serbs’ ‘naivety’ as exemplified in their choosing to create Yugoslavia at the end of the FirstWorldWar, and of, later, embracing communism. The article also offers a reassessment of the interwar period, often neglected by scholars of former Yugoslavia

From local laboratory data to public domain database in search of indirect association of diseases: AJAX based gene data search engine.

This paper presents an extensible schema for capturing laboratory gene variance data with its meta-data properties in a semi-structured environment. This paper also focuses on the issues of creating a local and task specific component database which is a subset of global data resources. An XML based genetic disorder component database schema is developed with adequate flexibilities to facilitate searching of gene mutation data. A web based search engine is developed that allows researchers to query a set of gene parameters obtained from local XML schema and subsequently allow them to automatically establish a link with the public domain gene databases. The application applies AJAX (Asynchronous Javascript and XML), a cutting-edge web technology, to carry out the gene data searching function