From local laboratory data to public domain database in search of indirect association of diseases: AJAX based gene data search engine.

Abstract

This paper presents an extensible schema for capturing laboratory gene variance data with its meta-data properties in a semi-structured environment. This paper also focuses on the issues of creating a local and task specific component database which is a subset of global data resources. An XML based genetic disorder component database schema is developed with adequate flexibilities to facilitate searching of gene mutation data. A web based search engine is developed that allows researchers to query a set of gene parameters obtained from local XML schema and subsequently allow them to automatically establish a link with the public domain gene databases. The application applies AJAX (Asynchronous Javascript and XML), a cutting-edge web technology, to carry out the gene data searching function