Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning

Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations. The problem of natural language applications is that they lack formality and the interpretation is not consistent. Conversely, ontologies can capture the intended meaning and specify modeling primitives. Disease Ontology (DO) that pertains to cancer's clinical stages and their corresponding information components is utilized to improve the reasoning ability of a decision support system (DSS). The proposed DSS uses Case-Based Reasoning (CBR) to consider disease manifestations and provides physicians with treatment solutions from similar previous cases for reference. The proposed DSS supports natural language processing (NLP) queries. The DSS obtained 84.63% accuracy in disease classification with the help of the ontology

Spatiotemporal patterns and predictability of cyberattacks

A relatively unexplored issue in cybersecurity science and engineering is whether there exist intrinsic patterns of cyberattacks. Conventional wisdom favors absence of such patterns due to the overwhelming complexity of the modern cyberspace. Surprisingly, through a detailed analysis of an extensive data set that records the time-dependent frequencies of attacks over a relatively wide range of consecutive IP addresses, we successfully uncover intrinsic spatiotemporal patterns underlying cyberattacks, where the term "spatio" refers to the IP address space. In particular, we focus on analyzing {\em macroscopic} properties of the attack traffic flows and identify two main patterns with distinct spatiotemporal characteristics: deterministic and stochastic. Strikingly, there are very few sets of major attackers committing almost all the attacks, since their attack "fingerprints" and target selection scheme can be unequivocally identified according to the very limited number of unique spatiotemporal characteristics, each of which only exists on a consecutive IP region and differs significantly from the others. We utilize a number of quantitative measures, including the flux-fluctuation law, the Markov state transition probability matrix, and predictability measures, to characterize the attack patterns in a comprehensive manner. A general finding is that the attack patterns possess high degrees of predictability, potentially paving the way to anticipating and, consequently, mitigating or even preventing large-scale cyberattacks using macroscopic approaches

Cybersecurity knowledge graphs

Cybersecurity knowledge graphs, which represent cyber-knowledge with a graph-based data model, provide holistic approaches for processing massive volumes of complex cybersecurity data derived from diverse sources. They can assist security analysts to obtain cyberthreat intelligence, achieve a high level of cyber-situational awareness, discover new cyber-knowledge, visualize networks, data flow, and attack paths, and understand data correlations by aggregating and fusing data. This paper reviews the most prominent graph-based data models used in this domain, along with knowledge organization systems that define concepts and properties utilized in formal cyber-knowledge representation for both background knowledge and specific expert knowledge about an actual system or attack. It is also discussed how cybersecurity knowledge graphs enable machine learning and facilitate automated reasoning over cyber-knowledge

Security Management Framework for the Internet of Things

The increase in the design and development of wireless communication technologies offers multiple opportunities for the management and control of cyber-physical systems with connections between smart and autonomous devices, which provide the delivery of simplified data through the use of cloud computing. Given this relationship with the Internet of Things (IoT), it established the concept of pervasive computing that allows any object to communicate with services, sensors, people, and objects without human intervention. However, the rapid growth of connectivity with smart applications through autonomous systems connected to the internet has allowed the exposure of numerous vulnerabilities in IoT systems by malicious users. This dissertation developed a novel ontology-based cybersecurity framework to improve security in IoT systems using an ontological analysis to adapt appropriate security services addressed to threats. The composition of this proposal explores two approaches: (1) design time, which offers a dynamic method to build security services through the application of a methodology directed to models considering existing business processes; and (2) execution time, which involves monitoring the IoT environment, classifying vulnerabilities and threats, and acting in the environment, ensuring the correct adaptation of existing services. The validation approach was used to demonstrate the feasibility of implementing the proposed cybersecurity framework. It implies the evaluation of the ontology to offer a qualitative evaluation based on the analysis of several criteria and also a proof of concept implemented and tested using specific industrial scenarios. This dissertation has been verified by adopting a methodology that follows the acceptance in the research community through technical validation in the application of the concept in an industrial setting.O aumento no projeto e desenvolvimento de tecnologias de comunicação sem fio oferece múltiplas oportunidades para a gestão e controle de sistemas ciber-físicos com conexões entre dispositivos inteligentes e autônomos, os quais proporcionam a entrega de dados simplificados através do uso da computação em nuvem. Diante dessa relação com a Internet das Coisas (IoT) estabeleceu-se o conceito de computação pervasiva que permite que qualquer objeto possa comunicar com os serviços, sensores, pessoas e objetos sem intervenção humana. Entretanto, o rápido crescimento da conectividade com as aplicações inteligentes através de sistemas autônomos conectados com a internet permitiu a exposição de inúmeras vulnerabilidades dos sistemas IoT para usuários maliciosos. Esta dissertação desenvolveu um novo framework de cibersegurança baseada em ontologia para melhorar a segurança em sistemas IoT usando uma análise ontológica para a adaptação de serviços de segurança apropriados endereçados para as ameaças. A composição dessa proposta explora duas abordagens: (1) tempo de projeto, o qual oferece um método dinâmico para construir serviços de segurança através da aplicação de uma metodologia dirigida a modelos, considerando processos empresariais existentes; e (2) tempo de execução, o qual envolve o monitoramento do ambiente IoT, a classificação de vulnerabilidades e ameaças, e a atuação no ambiente garantindo a correta adaptação dos serviços existentes. Duas abordagens de validação foram utilizadas para demonstrar a viabilidade da implementação do framework de cibersegurança proposto. Isto implica na avaliação da ontologia para oferecer uma avaliação qualitativa baseada na análise de diversos critérios e também uma prova de conceito implementada e testada usando cenários específicos. Esta dissertação foi validada adotando uma metodologia que segue a validação na comunidade científica através da validação técnica na aplicação do nosso conceito em um cenário industrial

Dynamic real-time risk analytics of uncontrollable states in complex internet of things systems, cyber risk at the edge

The Internet of Things (IoT) triggers new types of cyber risks. Therefore, the integration of new IoT devices and services requires a self-assessment of IoT cyber security posture. By security posture this article refers to the cybersecurity strength of an organisation to predict, prevent and respond to cyberthreats. At present, there is a gap in the state of the art, because there are no self-assessment methods for quantifying IoT cyber risk posture. To address this gap, an empirical analysis is performed of 12 cyber risk assessment approaches. The results and the main findings from the analysis is presented as the current and a target risk state for IoT systems, followed by conclusions and recommendations on a transformation roadmap, describing how IoT systems can achieve the target state with a new goal-oriented dependency model. By target state, we refer to the cyber security target that matches the generic security requirements of an organisation. The research paper studies and adapts four alternatives for IoT risk assessment and identifies the goal-oriented dependency modelling as a dominant approach among the risk assessment models studied. The new goal-oriented dependency model in this article enables the assessment of uncontrollable risk states in complex IoT systems and can be used for a quantitative self-assessment of IoT cyber risk posture