Higher aspirations: an agenda for reforming European universities

Since the introduction of the Shanghai ranking of the worldâ??s universities it has been clear that European universities are underperforming. This blueprint discusses the potential explanations and points at different reform priorities for higher education in Europe.

Empowering Citizens with Digital Twins: A Blueprint

The exponentially growing amount of digital information and data analysis increase the ability to perceive the holistic situation of people. This article applies the digital twin paradigm to strengthen a person's ability to utilize information about themselves by creating a digital representation of their situation to support their well-being. More specifically, we propose a blueprint to empower individuals by improving their self-determination regarding their personal data. The blueprint will help service and data providers, both public and private, to develop a common understanding of the role and possibilities of a citizen's controlled personal digital twin of themselves-a citizen digital twin (CDT)-for creating people-centric solutions. The blueprint also provides a rational framework for service development based on CDTs and serves as a basis for strategic guidance of service development. We demonstrate this with a case study of confirmation class students.Peer reviewe

Cell Death Response to DNA Damage.

The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer. From decades of clinical results, we learn that DDA have cured some cancers but their toxicity is temporary in most cancers due to emergence of DDA-resistant cancer cells. Investigation of DDA-activated genes, proteins, and pathways, known collectively as the DNA damage response (DDR), has uncovered the inner workings of DDR that protect the genome to sustain life. Paradoxically, however, DDR can also activate death. Current knowledge on DDA-activated death and hypotheses for how DDR may determine when and where to execute death are discussed. Given that cancer cells suffer from DDR defects, which account for their initial sensitivity to DDA, future therapeutic development may exploit those cancer-specific DDR defects to selectively create death-inducing DNA lesions, without using DDA, to kill DDA-resistant cancers

Supporting STEM students into STEM careers: A practical introduction for academics

Graduate employability is increasingly becoming a selection criteria used by students in their choice of university and discipline. It is also used as a metric for the quality assessment of institutions and the construction of the various league tables produced by newspapers and other media outlets. In addition to identifying levels of employment, further study and unemployment, graduates’ employment destinations are classified as “graduate” or “non-graduate” jobs. The distinction between “graduate” and “non-graduate” is also important for the various metrics that are produced from the destinations data.6 To evidence that a particular course or discipline supports graduate employability it is therefore important not only that graduates are able to find work, but also that they can find work of an appropriate level. A STEM degree should be a clear asset in achieving this aim of finding graduate level employment.National HE Stemm Programm

Helping Teens Help Themselves: A National Blueprint

This national blueprint represents a multi-year, multidisciplinary approach to increase supportive housing options for pregnant and parenting teens exiting foster care

Transition towards a social market economy? Limits and opportunities

The quest for an appropriate development and transition strategy in less developed countries (LDCs) and post-socialist countries (PSCs) has been studied for a long time, and it has been subject to numerous controversies among academics and development practitioners alike. Disputes have existed with respect to sequencing, timing, and pacing reforms, regarding the components of stabilization-cumadjustment programs, and also relating to the question which actors can become effective drivers of transition and development. Today, a widespread consensus exists that institutions and governance matter for making market-oriented policy reform succeed and that governments, despite the general need for less state interventionism, remain central actors for institution building and rule enforcement. The following considerations focus on the question whether or not the concept of the Social Market Economy, as it was originally developed and designed by German academics and policymakers more than fifty years ago, will be appropriate to guide policy and institutional reform in LDCs and PSCs and to make market-oriented reforms a viable policy choice in such countries regardless of their political regime. --Less developed countries,post-socialist countries,transition,social market economy

‘Filling the mattress’: Trust development in the governance of infrastructure megaprojects

The development of trust is a major challenge for the governance of public private infrastructure megaprojects. Contractual pre-arrangements should provide a blueprint for collaborative behavior and trust development but the characters of megaprojects challenge such arrangements. This longitudinal study explores practices of trust development in the collaboration of commissioner and contractor consortia in the Dutch road infrastructure megaproject ‘Schiphol, Amsterdam and Almere’ (SAA). The findings show that six different types of workshops have been used to intervene in the collaboration of project partners in order to develop trust. The study contributes to the debate on governance in megaprojects showing how governance arrangement are enacted in the daily practice in megaprojects. To buffer the potential loss of trust through conflicts, project partners negotiated for a balanced reciprocal relationship, which is the simultaneous exchange of equivalent resources without delay

Herald of Holiness Volume 57, Number 37 (1968)

02 Objection Overruled! By General Superintendent Coulter 03 In Spite of Adversities By Buford Battin 04 I Want to Be like Jesus By Eva J. Cummings 05 Hope for a Sick Society By Leslie Parrott 06 Pen Points: The Threat of Christianity By J. Rex Eaton 07 God\u27s Blueprint By Norman R. Oke 08 Prayer and Politics By J. V. Wilbanks 09 Just Happened to Think By Laura Forinash 10 Editorially Speaking By W.T. Purkiser 12 Evangelists\u27 Slates 15 Pro/Con: Letters to the Editor 16 The Book Corner 16 Of People and Places 17 News of Religion 19 Next Sunday\u27s Lesson by Albert J. Lown 19 The Answer Corner Conducted by W. T. Purkiserhttps://digitalcommons.olivet.edu/cotn_hoh/2437/thumbnail.jp