Safety Stock Placement Pada Perusahaan Farmasi Menggunakan Pendekatan Guaranteed-Service Dalam Jaringan Fasilitas Produksi

This study aims to understand the supply chain strategy of pharmaceutical companies, logistics drivers (facilities, inventory, and transportation), and cross-functional drivers (information, sources, and prices), as well as the problem of placing safety stock for assembly, using an integer linear approximation program using CPLEX to get the results and perform a sensitivity analysis. In this way, the effect of various parameters on total safety stock and service time can be estimated. Pharmaceutical companies can find strategic ways to align their goals with this method. The company already has an optimal supply chain focused on product quality, short response times, and product availability. In addition, it can minimize the total cost of safety inventory by using a piecewise linearization approach with a total assembly cost of Rp. 6,161,120,000, where safety stock is stored in stages 2-4, 7-14, 16, and 22, where 22 has the highest stage costs. Then a sensitivity analysis is carried out by allowing the parameters to vary, the more segments' total cost becomes stable. Furthermore, the relationship between the factors of safety, storage costs, and standard deviation is linear

An enhanced approximation mathematical model inventorying items in a multi-echelon system under a continuous review policy with probabilistic demand and lead-time

An inventory system attempts to balance between overstock and understock to reduce the total cost and achieve customer demand in a timely manner. The inventory system is like a hidden entity in a supply chain, where a large complete network synchronizes a series of interrelated processes for a manufacturer, in order to transform raw materials into final products and distribute them to customers. The optimality of inventory and allocation policies in a supply chain for a cement industry is still unknown for many types of multi-echelon inventory systems. In multi-echelon networks, complexity exists when the inventory issues appear in multiple tiers and whose performances are significantly affected by the demand and lead-time. Hence, the objective of this research is to develop an enhanced approximation mathematical model in a multi-echelon inventory system under a continuous review policy subject to probabilistic demand and lead-time. The probability distribution function of demand during lead-time is established by developing a new Simulation Model of Demand During Lead-Time (SMDDL) using simulation procedures. The model is able to forecast future demand and demand during lead-time. The obtained demand during lead-time is used to develop a Serial Multi-echelon Inventory (SMEI) model by deriving the inventory cost function to compute performance measures of the cement inventory system. Based on the performance measures, a modified distribution multi-echelon inventory (DMEI) model with the First Come First Serve (FCFS) rule (DMEI-FCFS) is derived to determine the best expected waiting time and expected number of retailers in the system based on a mean arrival rate and a mean service rate. This research established five new distribution functions for the demand during lead-time. The distribution functions improve the performance measures, which contribute in reducing the expected waiting time in the system. Overall, the approximation model provides accurate time span to overcome shortage of cement inventory, which in turn fulfil customer satisfaction

How to deal correctly with Lead Time in General Supply Chains

In the new global economy, the inventory control has become a priority for the supply chain management. Safety stock is the sole way to fight against the demand and the supply uncertainty, so determining the amount of it that must be kept along the network to holistically minimize the risk of disruption while maximize the profit is a critical issue. For the supply side, the focus is held in the lead time variability which can significantly vary depending on the part of the supply chain or new inconvenient facts could relevantly affect the lead time. Even so, developed models have forced to assume a certain value or a distribution for the lead time, yet this is risky. Historical data is often unreliable, not available or insufficiently representative. Therefore, a new model based on the Guaranteed Service approach and combined with robust optimization techniques is proposed, working with the lead time volatility without assuming any specific distribution. Interesting features arise from the new model such as the smooth tractability of the problem, the facile computational skills required or the lack of resources needed. This approach has been formulated and tested, as well as the Guaranteed Service when a distribution is assumed for the lead time and the original model. Then, the performance of the three of them has been compared in order to find the correct way to deal with uncertain lead time. Finally, the Robust Guaranteed model benefits promise better security to companies and it also provides a powerful tool to manage the risk from the supply side.Outgoin