Acetylcholine neuromodulation in normal and abnormal learning and memory: vigilance control in waking, sleep, autism, amnesia, and Alzheimer's disease

This article provides a unified mechanistic neural explanation of how learning, recognition, and cognition break down during Alzheimer's disease, medial temporal amnesia, and autism. It also clarifies whey there are often sleep disturbances during these disorders. A key mechanism is how acetylcholine modules vigilance control in cortical layer

Cortical Dynamics of Navigation and Steering in Natural Scenes: Motion-Based Object Segmentation, Heading, and Obstacle Avoidance

Visually guided navigation through a cluttered natural scene is a challenging problem that animals and humans accomplish with ease. The ViSTARS neural model proposes how primates use motion information to segment objects and determine heading for purposes of goal approach and obstacle avoidance in response to video inputs from real and virtual environments. The model produces trajectories similar to those of human navigators. It does so by predicting how computationally complementary processes in cortical areas MT-/MSTv and MT+/MSTd compute object motion for tracking and self-motion for navigation, respectively. The model retina responds to transients in the input stream. Model V1 generates a local speed and direction estimate. This local motion estimate is ambiguous due to the neural aperture problem. Model MT+ interacts with MSTd via an attentive feedback loop to compute accurate heading estimates in MSTd that quantitatively simulate properties of human heading estimation data. Model MT interacts with MSTv via an attentive feedback loop to compute accurate estimates of speed, direction and position of moving objects. This object information is combined with heading information to produce steering decisions wherein goals behave like attractors and obstacles behave like repellers. These steering decisions lead to navigational trajectories that closely match human performance.National Science Foundation (SBE-0354378, BCS-0235398); Office of Naval Research (N00014-01-1-0624); National Geospatial Intelligence Agency (NMA201-01-1-2016

Wide baseline pose estimation from video with a density-based uncertainty model

International audienceRobust wide baseline pose estimation is an essential step in the deployment of smart camera networks. In this work, we highlight some current limitations of conventional strategies for relative pose estimation in difficult urban scenes. Then, we propose a solution which relies on an adaptive search of corresponding interest points in synchronized video streams which allows us to converge robustly toward a high-quality solution. The core idea of our algorithm is to build across the image space a nonstationary mapping of the local pose estimation uncertainty, based on the spatial distribution of interest points. Subsequently, the mapping guides the selection of new observations from the video stream in order to prioritize the coverage of areas of high uncertainty. With an additional step in the initial stage, the proposed algorithm may also be used for refining an existing pose estimation based on the video data; this mode allows for performing a data-driven self-calibration task for stereo rigs for which accuracy is critical, such as onboard medical or vehicular systems. We validate our method on three different datasets which cover typical scenarios in pose estimation. The results show a fast and robust convergence of the solution, with a significant improvement, compared to single image-based alternatives, of the RMSE of ground-truth matches, and of the maximum absolute error

Exploiting correlogram structure for robust speech recognition with multiple speech sources

This paper addresses the problem of separating and recognising speech in a monaural acoustic mixture with the presence of competing speech sources. The proposed system treats sound source separation and speech recognition as tightly coupled processes. In the first stage sound source separation is performed in the correlogram domain. For periodic sounds, the correlogram exhibits symmetric tree-like structures whose stems are located on the delay that corresponds to multiple pitch periods. These pitch-related structures are exploited in the study to group spectral components at each time frame. Local pitch estimates are then computed for each spectral group and are used to form simultaneous pitch tracks for temporal integration. These processes segregate a spectral representation of the acoustic mixture into several time-frequency regions such that the energy in each region is likely to have originated from a single periodic sound source. The identified time-frequency regions, together with the spectral representation, are employed by a `speech fragment decoder' which employs `missing data' techniques with clean speech models to simultaneously search for the acoustic evidence that best matches model sequences. The paper presents evaluations based on artificially mixed simultaneous speech utterances. A coherence-measuring experiment is first reported which quantifies the consistency of the identified fragments with a single source. The system is then evaluated in a speech recognition task and compared to a conventional fragment generation approach. Results show that the proposed system produces more coherent fragments over different conditions, which results in significantly better recognition accuracy

Representation Learning: A Review and New Perspectives

The success of machine learning algorithms generally depends on data representation, and we hypothesize that this is because different representations can entangle and hide more or less the different explanatory factors of variation behind the data. Although specific domain knowledge can be used to help design representations, learning with generic priors can also be used, and the quest for AI is motivating the design of more powerful representation-learning algorithms implementing such priors. This paper reviews recent work in the area of unsupervised feature learning and deep learning, covering advances in probabilistic models, auto-encoders, manifold learning, and deep networks. This motivates longer-term unanswered questions about the appropriate objectives for learning good representations, for computing representations (i.e., inference), and the geometrical connections between representation learning, density estimation and manifold learning

Neural network-based shape retrieval using moment invariants and Zernike moments.

Shape is one of the fundamental image features for use in Content-Based Image Retrieval (CBIR). Compared with other visual features such as color and texture, it is extremely powerful and provides capability for object recognition and similarity-based image retrieval. In this thesis, we propose a Neural Network-Based Shape Retrieval System using Moment Invariants and Zernike Moments. Moment Invariants and Zernike Moments are two region-based shape representation schemes and are derived from the shape in an image and serve as image features. k means clustering is used to group similar images in an image collection into k clusters whereas Neural Network is used to facilitate retrieval against a given query image. Neural Network is trained by the clustering result on all of the images in the collection using back-propagation algorithm. In this scheme, Neural Network serves as a classifier such that moments are inputs to the Neural Network and the output is one of the k classes that have the largest similarities to the query image. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis2005 .C444. Source: Masters Abstracts International, Volume: 44-03, page: 1396. Thesis (M.Sc.)--University of Windsor (Canada), 2005

Never a \u27needless\u27 suicide: An empirical test of Shneidman\u27s theory of psychological needs, psychological pain, and suicidality (Edwin Shneidman).

The phenomenology of suicidal thoughts and behaviour has been an area of increased interest in recent years. One particular area of focus is psychological pain, or psychache. In this dissertation, Edwin Shneidman\u27s psychological theory of suicide was studied. Shneidman has theorized that psychological needs are associated with the development of psychological pain, which in turn leads to suicide as an escape from pain. Two hundred and fifty-seven undergraduate students completed the Personality Research Form, the Psychache Scale, the Orbach and Mikulincer Mental Pain Scale, two items from Shneidman\u27s Psychological Pain Assessment Scale, as well as demographic and suicide history items. Measures of psychological pain demonstrated convergent validity. Low need for affiliation and high impulsivity were significantly related to psychological pain. All measures of psychological pain were associated with suicidal ideation and history of suicide attempts. Possible gender differences emerged. This study provides some evidence for Shneidman\u27s theory, although not all identified needs were supported. The importance of understanding the role of psychological pain in the phenomenology of suicidal thinking and behaviour is emphasized.Dept. of Psychology. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis2005 .D375. Source: Dissertation Abstracts International, Volume: 66-11, Section: B, page: 6267. Thesis (Ph.D.)--University of Windsor (Canada), 2005

Improving acoustic vehicle classification by information fusion

We present an information fusion approach for ground vehicle classification based on the emitted acoustic signal. Many acoustic factors can contribute to the classification accuracy of working ground vehicles. Classification relying on a single feature set may lose some useful information if its underlying sound production model is not comprehensive. To improve classification accuracy, we consider an information fusion diagram, in which various aspects of an acoustic signature are taken into account and emphasized separately by two different feature extraction methods. The first set of features aims to represent internal sound production, and a number of harmonic components are extracted to characterize the factors related to the vehicle’s resonance. The second set of features is extracted based on a computationally effective discriminatory analysis, and a group of key frequency components are selected by mutual information, accounting for the sound production from the vehicle’s exterior parts. In correspondence with this structure, we further put forward a modifiedBayesian fusion algorithm, which takes advantage of matching each specific feature set with its favored classifier. To assess the proposed approach, experiments are carried out based on a data set containing acoustic signals from different types of vehicles. Results indicate that the fusion approach can effectively increase classification accuracy compared to that achieved using each individual features set alone. The Bayesian-based decision level fusion is found fusion is found to be improved than a feature level fusion approac