7 research outputs found

    Factors moderating the risk of PTSD, emotional and behavioral problems amongst children in war zones and refugees escaping from warfare

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    Children who grow up in war zones are typically exposed to multiple stressors including physical harm, intimidation or other forms of psychological trauma. This can also lead to Post Traumatic Stress Disorder. On the other hand, resilient children show no psychiatric distress even when they are exposed to severe traumatic stress. Additionally, the number of refugee children due to warfare reasons is increasing. Past empirical studies have recognized that the process of migration and living life as a refugee is detrimental to the psychological health of young refugees. In this symposium we will examine the prevalence and determinants of resiliency among refugee children and children living in conditions of war and violence. The first study investigated the psychological, social and somatic effects of chronic traumatic experience on Palestinian children over six years (2000-2006). The sample consisted of 1,137 children who completed: Checklist of Traumatic Experiences, Symptoms of PTSD Scale, Network of Psycho-Social Support and Personality Assessment Questionnaire. It was found that 41% of the participants suffered from PTSD. From these 25% suffered from cognitive symptoms; 22% suffered from emotional symptoms; 22% suffered from social behavioral problems; 17% suffered from academic and 14% suffered from somatic symptoms. The support of family, friends, relatives and teachers, and positive personality traits were found to be strong protective factors aiding recovery from trauma and PTSD. The second study evaluated the relation of exposure to war traumas, and violence in the family, community, and school, to PTSD symptoms, emotional and behavioral problems amongst 330 Palestinian children. Results highlight the additive effects of exposure to war traumas and violence in different settings. In addition, it was found that psychosocial support reduced the effects of environmental factors in developing PTSD and behavioral problems. The third study included data from two refugee charity organizations in the UK. There were 200 refugee children coming from war zones and 210 control children (non-refugees). The study aimed to look at a range of factors to assess the differences between the above groups with regards to their well-being and peer and sibling relationships. Results showed that refugee children were significantly more likely to be in the clinical range for total difficulties and to have higher health and physical problems, negative friendship quality and low self esteem compared to the control group. Refugees who were bullied at home and at school were also more likely to develop PTSD symptoms. Protective factors are also discussed in this study. The above studies emphasize the fact that interventionists should consider the full range of sources of environmental risk for PTSD and emotional and behavioral problems and should strengthen the psychosocial support for children in or coming from war zones

    Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis

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    Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitization patterns (mono- or pauci-sensitization versus polysensitization), (iii) severity of symptoms, and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and autoimmune diseases

    Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesis

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    Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.info:eu-repo/semantics/publishedVersio

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