2,295 research outputs found
Analysis on the Business Model of Fresh E-commerce------Taking Hema Supermarket as an Example
Enterprises are beginning to involve the fresh produce industry, but most companies have withdrawn from the fresh produce industry due to poor performance. This shows that there are many problems with e-commerce of fresh produce. In particular, the business model of e-commerce for fresh produce is a major factor constraining its development. This article takes Hema Supermarket as an example to analyze its business model. It summarizes the areas that can be used for product control, power distribution system construction, platform operation, etc., and provides reference and reference for the operation of fresh agricultural products
Enzyme kinetics, molecular docking, and in silico characterization of canary seed (Phalaris canariensis L.) peptides with ACE and pancreatic lipase inhibitory activity
The bioactivity of canary seed peptides (CSP) towards metabolism-regulating enzymes was evaluated. Peptides with angiotensin-converting enzyme (ACE), dipeptidyl peptidase IV (DPP-IV), and pancreatic lipase activity remained stable (p \u3c 0.05) to simulated gastrointestinal digestion (SGD). CSP-SGD were transported efficiently (\u3e10%) through the Caco-2 monolayer, indicating absorption through the intestinal epithelium. Lineweaver-Burk plots demonstrated that CSP-SGD act as mixed-type inhibitors for DPP-IV and α-glucosidase. Furthermore, CSP-SGD were potent as antihypertensive and antiobesity agents. Molecular docking and in silico analyses were targeted to understand CSP-SGD interactions with ACE and pancreatic lipase. ACE-inhibitory peptides (LHPQ, QTPHQ, KPVPR, and ELHPQ) acted as non-competitive inhibitors by destabilization of the transition state and Zn(II) coordination in ACE. The uncompetitive inhibition of pancreatic lipase by peptides (VPPR, LADR, LSPR, and TVGPR) destabilized the open-lid conformation of pancreatic lipase. The results of this study showed that canary seed proteins could serve as a source of biologically active peptides
Herbicides
Herbicides are one of the most widely used groups of pesticides worldwide for controlling weedy species in agricultural and non-crop settings. Due to the extensive use of herbicides and their value in weed management, herbicide research remains crucial for ensuring continued effective use of herbicides while minimizing detrimental effects to ecosystems. Presently, a wide range of research continues to focus on the physiology of herbicide action, the environmental impact of herbicides, and safety. The authors of Herbicides, Physiology of Action, and Safety cover multiple topics concerning current valuable herbicide research
Sustainable Freight Village Concepts for Agricultural Products Logistics - A Knowledge Management-oriented Study
Freight villages (FVs) are logistics phenomenon with broad economic, environmental, and social consequences. This research extends sustainability in the context of FVs to twofold meanings. This includes the sustainable development of FVs, and the sustainability contributions they created. China has showed a more recent but quicker story in developing FVs. Nevertheless, a number of problems and limits exist. Taking China as research background, this research consists of theoretical explorations, status quo analysis, and practical applications in agricultural products logistics (APL). This research proposes that knowledge management (KM) is the most desirable option to reach sustainable values of FVs. The status quo analysis examines the adaption of FVs to China s current logistics situation. It identifies several orientations for the next development step of FVs. To cope with the pervasive problems during FV planning stage, this research adopts sense-making KM approach to guide a systematic planning process including sense making, knowledge creation, and decision making. In order to achieve a high sustainability rating, this research uses KM cycle model to generate synergies among major stakeholders of FVs. Moreover, it proposes a roadmap for organizing KM process so as to build sustainability capability. Three key elements for the roadmap are identified: human ability, stakeholder engagement, and information system. This research focuses on the application of sustainable FV concepts for agricultural products logistics (APL). It deals with issues affecting city logistics and agricultural products (agri-products) supply in China. This can make best use of FV functions from a sustainability perspective. Agri-FV is proposed to bring professional logistics facilities and services, efficient distribution of agri-products, and information-based operations. An integrated APL system is structured consisting of farmers cooperatives, chain stores, and agri-FVs. In this system, agri-FV plays an important role in levering sustainability outcomes. Furthermore, KM approaches are applied to agri-FV project planning and operations, meanwhile considering the characteristics of agri-products and APL
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The design and synthesis of Novel AOX and cytochrome bc1 complex inhibitors which act as phytopathogenic fungicides
The metabolic pathway for oxidative phosphorylation has remained a reliable target for the development of novel fungicides. The reliance on single target site fungicides within this pathway has increased the selection pressure for point mutations within a number of key complexes, including the cytochrome bc1 complex. The alternative oxidase (AOX) provides an alternative route for respiration, introducing a mechanism by which selection pressure and pathogenicity can be increased. In particular, the fungal pathogen Septoria tritici has developed a highly fungicide resistant strain. The design and synthesis of inhibitors targeting the fungal AOX, or the AOX and the cytochrome bc1 complex, represents a new class of fungicides improving crop yield outcomes.
Investigation into the AOX found in S. tritici (StAOX), led to new techniques to fully characterise and overexpress the protein in a haem deficient Escherichia coli strain, which has then been compared to that of the well-studied protozoan AOX, Trypanosoma brucei brucei (TAO). The enzymatic activity of StAOX was found to be significantly lower in comparison to AOXs from other species, but responded dramatically to the nucleotide regulators, GMP and IMP. The purified protein has also been shown to be sensitive to its lipid environment with full enzymatic recovery following re-introduction into a lipid membrane.
The natural quinol analogue, ascofuranone, displays selectivity towards the AOX and was selected for further design and lead modification. Several ascofuranone derivatives were synthesised according to a new synthetic route. A variety of new methods were utilised to analyse the inhibitors providing IC50, KD, thermodynamic and cytotoxicity data. Two of the newly synthesised compounds provided selectivity for TAO over the cytochrome bc1 complex, but failed to show selectivity to the StAOX. In vitro data suggests a single phenylalanine residue restricts inhibitor’s tail length to within an 8-carbon chain length, supported by an in-silico docking screen
Green Logistics development and evaluation of the carbon footprint
Along with the worldwide climate changing, human activities and the rapid deterioration of the environment, Low-carbon economy in recent years become increasingly focus of attention in people's lives. The economic reform will gradually penetrate into the logistics system, modern logistics as a composite service industry, play a decisive role in the modern division of labor and cooperation under the social environment, it is a manufacturing! The important supporting business is an important bridge between production and consumption. The logistics industry is in a period of rapid development, the logistics process not only energy consumption demand is big, and the C02 emissions are also large. Coupled with the destruction of the human living environment, the greenhouse effect becomes more and more prominent, more the need of the development of green logistics, low carbon logistics. However, at home and abroad for most of the research of this aspect is still stay in the stage of qualitative analysis, quantitative analysis of the literature on energy consumption and C02 emission of less amount of logistics system. There are four objectives will be discussed.
The first objective is the relevant literature on the green logistics is summarized, which lays the foundation for the research in this paper, green logistics. The second objective is the energy consumption and C02 calculation models were summarized, to provide reference for other scholars to conduct relevant research. The third objective is through statistical analysis, master the different modes of transport energy consumption and C02 emissions, and provide the basis for enterprises to choose the mode of transport. The fourth objective combining with specific examples, analyzed the carbon footprint of the logistics process instance modeling based on LCA.fi=Opinnäytetyö kokotekstinä PDF-muodossa.|en=Thesis fulltext in PDF format.|sv=Lärdomsprov tillgängligt som fulltext i PDF-format
International Conference on Advances in Biosciences and Biotechnology – ICABB-2019
International Conference on Advances in Biosciences and Biotechnology – ICABB-201
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