9,352 research outputs found
Programmable models of growth and mutation of cancer-cell populations
In this paper we propose a systematic approach to construct mathematical
models describing populations of cancer-cells at different stages of disease
development. The methodology we propose is based on stochastic Concurrent
Constraint Programming, a flexible stochastic modelling language. The
methodology is tested on (and partially motivated by) the study of prostate
cancer. In particular, we prove how our method is suitable to systematically
reconstruct different mathematical models of prostate cancer growth - together
with interactions with different kinds of hormone therapy - at different levels
of refinement.Comment: In Proceedings CompMod 2011, arXiv:1109.104
Dynamics of Internal Models in Game Players
A new approach for the study of social games and communications is proposed.
Games are simulated between cognitive players who build the opponent's internal
model and decide their next strategy from predictions based on the model. In
this paper, internal models are constructed by the recurrent neural network
(RNN), and the iterated prisoner's dilemma game is performed. The RNN allows us
to express the internal model in a geometrical shape. The complicated
transients of actions are observed before the stable mutually defecting
equilibrium is reached. During the transients, the model shape also becomes
complicated and often experiences chaotic changes. These new chaotic dynamics
of internal models reflect the dynamical and high-dimensional rugged landscape
of the internal model space.Comment: 19 pages, 6 figure
Network Automata: Coupling structure and function in real-world networks
We introduce Network Automata, a framework which couples the topological
evolution of a network to its structure. It is useful for dealing with networks
in which the topology evolves according to some specified microscopic rules
and, simultaneously, there is a dynamic process taking place on the network
that both depends on its structure but is also capable of modifying it. It is a
generic framework for modeling systems in which network structure, dynamics,
and function are interrelated. At the practical level, this framework allows
for easy implementation of the microscopic rules involved in such systems. To
demonstrate the approach, we develop a class of simple biologically inspired
models of fungal growth.Comment: 7 pages, 5 figures, 1 tables. Revised content - surplus text and
figures remove
A guided tour of asynchronous cellular automata
Research on asynchronous cellular automata has received a great amount of
attention these last years and has turned to a thriving field. We survey the
recent research that has been carried out on this topic and present a wide
state of the art where computing and modelling issues are both represented.Comment: To appear in the Journal of Cellular Automat
A Spatial Agent-Based Model of N-Person Prisoner's Dilemma Cooperation in a Socio-Geographic Community
The purpose of this paper is to present a spatial agent-based model of N-person prisoner's dilemma that is designed to simulate the collective communication and cooperation within a socio-geographic community. Based on a tight coupling of REPAST and a vector Geographic Information System, the model simulates the emergence of cooperation from the mobility behaviors and interaction strategies of citizen agents. To approximate human behavior, the agents are set as stochastic learning automata with Pavlovian personalities and attitudes. A review of the theory of the standard prisoner's dilemma, the iterated prisoner's dilemma, and the N-person prisoner's dilemma is given as well as an overview of the generic architecture of the agent-based model. The capabilities of the spatial N-person prisoner's dilemma component are demonstrated with several scenario simulation runs for varied initial cooperation percentages and mobility dynamics. Experimental results revealed that agent mobility and context preservation bring qualitatively different effects to the evolution of cooperative behavior in an analyzed spatial environment.Agent Based Modeling, Cooperation, Prisoners Dilemma, Spatial Interaction Model, Spatially Structured Social Dilemma, Geographic Information Systems
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