Sustainable Design and Building Information Modelling: Case Study of Energy Plus House, Hieron's Wood, Derbyshire UK

In this paper the method for sustainable design analysis (SDA) integration with building information modelling (BIM) is explored, through the prism of a complex case study based research. BIM model federation and integration challenges are reported, including issues with combining geometry and managing attribute data. The research defines SDA as rapid and quantifiable analysis of multitude of sustainable alternatives and ‘what if’ questions posed by a design team during the early stages of the project, when the benefits of correct decisions can significantly exceed the actual investment required. The SDA concept and BIM integration findings are explained from conceptualisation to calculation stage, emphasising the importance of an iterative over a linear approach. The research approach adopted has led to more informed sustainable solutions at earlier stages of project development, with a generally lower level of development (LOD) and computational/modelling effort required

Hydrodynamic Processes in Massive Stars

The hydrodynamic processes operating within stellar interiors are far richer than represented by the best stellar evolution model available. Although it is now widely understood, through astrophysical simulation and relevant terrestrial experiment, that many of the basic assumptions which underlie our treatments of stellar evolution are flawed, we lack a suitable, comprehensive replacement. This is due to a deficiency in our fundamental understanding of the transport and mixing properties of a turbulent, reactive, magnetized plasma; a deficiency in knowledge which stems from the richness and variety of solutions which characterize the inherently non-linear set of governing equations. The exponential increase in availability of computing resources, however, is ushering in a new era of understanding complex hydrodynamic flows; and although this field is still in its formative stages, the sophistication already achieved is leading to a dramatic paradigm shift in how we model astrophysical fluid dynamics. We highlight here some recent results from a series of multi-dimensional stellar interior calculations which are part of a program designed to improve our one-dimensional treatment of massive star evolution and stellar evolution in general.Comment: 10 pages, 4 figures, IAUS 252 Conference Proceeding (Sanya) - "The Art of Modeling Stars in the 21st Century

Simulated single molecule microscopy with SMeagol

SMeagol is a software tool to simulate highly realistic microscopy data based on spatial systems biology models, in order to facilitate development, validation, and optimization of advanced analysis methods for live cell single molecule microscopy data. Availability and Implementation: SMeagol runs on Matlab R2014 and later, and uses compiled binaries in C for reaction-diffusion simulations. Documentation, source code, and binaries for recent versions of Mac OS, Windows, and Ubuntu Linux can be downloaded from http://smeagol.sourceforge.net.Comment: v2: 14 pages including supplementary text. Pre-copyedited, author-produced version of an application note published in Bioinformatics following peer review. The version of record, and additional supplementary material is available online at: https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btw10