28,362 research outputs found
Derivation of diagnostic models based on formalized process knowledge
© IFAC.Industrial systems are vulnerable to faults. Early and accurate detection and diagnosis in production systems can minimize down-time, increase the safety of the plant operation, and reduce manufacturing costs. Knowledge- and model-based approaches to automated fault detection and diagnosis have been demonstrated to be suitable for fault cause analysis within a broad range of industrial processes and research case studies. However, the implementation of these methods demands a complex and error-prone development phase, especially due to the extensive efforts required during the derivation of models and their respective validation. In an effort to reduce such modeling complexity, this paper presents a structured causal modeling approach to supporting the derivation of diagnostic models based on formalized process knowledge. The method described herein exploits the Formalized Process Description Guideline VDI/VDE 3682 to establish causal relations among key-process variables, develops an extension of the Signed Digraph model combined with the use of fuzzy set theory to allow more accurate causality descriptions, and proposes a representation of the resulting diagnostic model in CAEX/AutomationML targeting dynamic data access, portability, and seamless information exchange
Inference of the genetic network regulating lateral root initiation in Arabidopsis thaliana
Regulation of gene expression is crucial for organism growth, and it is one of the challenges in Systems Biology to reconstruct the underlying regulatory biological networks from transcriptomic data. The formation of lateral roots in Arabidopsis thaliana is stimulated by a cascade of regulators of which only the interactions of its initial elements have been identified. Using simulated gene expression data with known network topology, we compare the performance of inference algorithms, based on different approaches, for which ready-to-use software is available. We show that their performance improves with the network size and the inclusion of mutants. We then analyse two sets of genes, whose activity is likely to be relevant to lateral root initiation in Arabidopsis, by integrating sequence analysis with the intersection of the results of the best performing methods on time series and mutants to infer their regulatory network. The methods applied capture known interactions between genes that are candidate regulators at early stages of development. The network inferred from genes significantly expressed during lateral root formation exhibits distinct scale-free, small world and hierarchical properties and the nodes with a high out-degree may warrant further investigation
A kernel-based framework for learning graded relations from data
Driven by a large number of potential applications in areas like
bioinformatics, information retrieval and social network analysis, the problem
setting of inferring relations between pairs of data objects has recently been
investigated quite intensively in the machine learning community. To this end,
current approaches typically consider datasets containing crisp relations, so
that standard classification methods can be adopted. However, relations between
objects like similarities and preferences are often expressed in a graded
manner in real-world applications. A general kernel-based framework for
learning relations from data is introduced here. It extends existing approaches
because both crisp and graded relations are considered, and it unifies existing
approaches because different types of graded relations can be modeled,
including symmetric and reciprocal relations. This framework establishes
important links between recent developments in fuzzy set theory and machine
learning. Its usefulness is demonstrated through various experiments on
synthetic and real-world data.Comment: This work has been submitted to the IEEE for possible publication.
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SNE: Signed Network Embedding
Several network embedding models have been developed for unsigned networks.
However, these models based on skip-gram cannot be applied to signed networks
because they can only deal with one type of link. In this paper, we present our
signed network embedding model called SNE. Our SNE adopts the log-bilinear
model, uses node representations of all nodes along a given path, and further
incorporates two signed-type vectors to capture the positive or negative
relationship of each edge along the path. We conduct two experiments, node
classification and link prediction, on both directed and undirected signed
networks and compare with four baselines including a matrix factorization
method and three state-of-the-art unsigned network embedding models. The
experimental results demonstrate the effectiveness of our signed network
embedding.Comment: To appear in PAKDD 201
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