Seroprevalence of Newcastle disease in indigenous chickens in Ilorin, Kwara State, Nigeria

Newcastle disease (ND) is a disease of high economic importance to poultry farmers in Nigeria. Its impact on poultry include illness of poultry, reduction in egg production, immunosuppression, and death. This study was carried out to determine the prevalence of Newcastle disease in indigenous (local) chickens from 2 poultry abattoirs in the Ilorin metropolis. A total of 400 blood samples were aseptically collected in plain bottles from the jugular veins of local chickens at slaughter using exsanguination and transported to the laboratory in batches. Sera samples were harvested from the blood by centrifugation at 3000 rpm for 10 minutes, after which they were stored at -20oC before serological assay. The sera were subjected to Haemagglutination Inhibition (HI) test to check for the presence of Newcastle disease virus (NDV) antibody following a standard procedure with titer values for each sample recorded. The geometric mean of the HI antibody titer (GMT) and the percentages of detectable NDV HI antibody titer were calculated using descriptive statistics. Of the 400 serum samples examined, 53 (13.25%) were positive for ND antibodies, with titre value ≥ 1:16. The location from which the birds were selected had no significant relationship with the prevalence of ND antibodies as both Oja tuntun (11.9%), and Ipata market (14.6%) had a closely similar prevalence of antibodies (p > 0.05). The feather arrangement of birds did not also have any significant impact on the prevalence of antibodies (p > 0.05). However, in this study, we observed a higher prevalence of antibodies among hens (14.7%) than in cocks (12.5%) or growers (8.9%). The high prevalence of ND antibodies in indigenous chickens in the study area showed the endemicity of the disease in the study areas. With most of the chickens are not vaccinated amid non-compliance to vaccine administration for local chickens. There is a need for poultry farmers in the study location to be educated on the importance of vaccinating poultry birds against ND

Seroprevalence and risk factors associated with Newcastle disease in backyard chickens in West Kordofan State, Sudan

Background and Aim: Newcastle disease (ND), a major constraint to poultry production worldwide, is a highly contagious disease of many species of domestic, exotic, and wild birds caused by ND virus (NDV). Epidemiological studies are lacking regarding ND in village chickens, including the traditional and intensive production systems used in Sudan. However, it is necessary to develop appropriate strategies to control the disease. Therefore, this study aimed to estimate the flock- and bird-level seroprevalence of NDV in backyard chickens in West Kordofan State, Sudan, and to identify the risk factors associated with ND in the study area. Materials and Methods: The seroprevalence of the circulating NDV and bird-level risk factors associated with ND was determined in backyard chickens from March to October 2017, in six villages (Alnowara, Alleait, Geibaish, Baiad, Sougoh, and Alnuhoud) in the Geibaish and Elnuhoud localities of West Kordofan State. Results: Using the hemagglutination-inhibition test, the bird- and flock-level seroprevalences of antibodies to NDV were estimated as 20.6% (78/378) and 45% (18/40), respectively. Bird-level NDV seropositivity in backyard chickens was significantly associated with the reason for raising chickens, type of housing, contact with neighboring poultry, contact with wild birds, and chicken mortality caused by infectious diseases (p ≤ 0.05). Conclusion: This study indicated that NDV is circulating in backyard chickens and may act as a potential source of infection for other birds and thus persistence of ND among local traditionally managed chickens in the areas of West Kordofan State. Risk factors contributing to ND occurrence are important for designing appropriate prevention and control strategies

Financial costs of disease burden, morbidity and mortality from priority livestock diseases in Nigeria: Disease burden and cost-benefit analysis of targeted interventions

Nigeria’s agriculture sector generates one-third of its Gross Domestic Product (GDP) and employs two-thirds of the workforce. Its recent growth dominates Nigerian non-oil economic growth. Small-scale, semi-commercial farms, settled agricultural households and transhumant pastoralists dominate production. Livestock is the second largest agricultural sub-sector and features 16.43 million cattle, 34.69 million sheep, 55.15 million goats, 7.18 million pigs and 183.16 million poultry. These provide nutrition and food security, and a range of services including draught power for cropping activities. Poor animal productivity is widely attributed to the occurrence and endemicity of certain animal diseases. These are often unreported, unconfirmed or poorly documented. The financial losses associated with such outbreaks and costs associated with the disease burden are also rarely documented. Efforts at control of such animal diseases have yielded poor returns due to ineffective or absent control programs, insufficient inputs (such as vaccines), poor vaccination coverage due to limited vaccine supplies and constraints in field mobility and support funds, illiteracy of farmers and poor management systems. In preparation for the World Bank’s Integrated Animal and Human Health Management project for Nigeria, estimates of the economic and financial implications of high disease burden, morbidity and mortality and the costs of implementing various interventions, for all or a combination of priority diseases were required. The Government of Nigeria invited ILRI to provide such estimates for priority diseases: NCD in rural poultry flocks; PPR in sheep and goats; CBPP in cattle; ASF in pigs; and trypanosomosis in ruminants and pigs. For these diseases, and across agroecological zones, the study’s objectives were to: • assess the direct and indirect financial burden of inaction; • estimate the costs of targeted interventions; • determine the additional benefits, additional costs and net benefits associated with interventions; • evaluate of the benefit-cost ratios (BCRs) of targeted interventions; and • make recommendations on the feasibility of the targeted interventions. The study featured epidemiology and economic components. Spreadsheet-based economic modelling was effectively combined with participatory epidemiological fieldwork and analysis, and both national and international specialists contributed. Both primary and secondary data were obtained, and stakeholder consultations and expert interviews were conducted. An extensive literature review was compiled

Emerg Infect Dis

PMC4550154611