15,575 research outputs found
The Death Penalty and Reversible Error in Massachusetts
[Excerpt] “This article will survey Massachusetts homicide cases from 1805 to 1996 in which the SJC found reversible error. For comparative purposes, the data will be grouped into three periods: from 1805, the year the SJC began to publish its decisions, to 1891, the year original jurisdiction for homicide cases was transferred from the SJC to the Superior Court; 1892 to 1939, the year Massachusetts law allowed the SJC to review the facts as well as the law of capital cases; and from 1940 to 1996, the year Chief Justice Paul Liacos resigned from the court and the importance of state constitutionalism declined. First, the data on reversible error will be situated within its proper legal-historical context and analyzed. Second, using key cases, this article will illustrate some of the major changes in criminal procedure initiated by the court’s finding of reversible error. I argue that the sharp increase in the number of homicide cases in which the SJC found reversible error and the resulting transformation of capital procedure was stimulated chiefly by the SJC’s commitment to state constitutionalism after Warren’s retirement in 1969. For these reasons, from 1970 to 1996 the SJC reversed a greater percentage of capital cases than ever before in its long history. Most importantly, in 1975 the court abolished the mandatory death penalty for murder committed during a rape and in three subsequent opinions found the death penalty violated Articles 12 and 26 of the Massachusetts Declaration of Rights.
The WiRE Summer 2019
The Summer 2019 issue of The WiRE covers the Professor Andy Nash\u27s departure from Southern Adventist University and an SJC adjunct\u27s win of a top journalism honor. Also featured is the remodel of the SJC office and photography studio, recent SJC graduates, and department award winners.https://knowledge.e.southern.edu/wire/1003/thumbnail.jp
Coculture of bovine cartilage with synovium and fibrous joint capsule increases aggrecanase and matrix metalloproteinase activity
Background
A hallmark of osteoarthritis is increased proteolytic cleavage of aggrecan. Cross talk between cartilage and the synovium + joint capsule (SJC) can drive cartilage degradation by activating proteases in both tissues. We investigated aggrecan proteolysis patterns in cartilage explants using a physiologically relevant explant model of joint injury combining cartilage mechanical compression and coincubation with SJC.
Methods
Bovine cartilage explants were untreated; coincubated with SJC; or subjected to mechanical injury and coincubated with SJC, mechanical injury alone, or mechanical injury and incubated with tumor necrosis factor-α (TNF-α). To compare the patterns of aggrecan proteolysis between 6 h and 16 days, release of sulfated glycosaminoglycans and specific proteolytic aggrecan fragments into medium or remaining in cartilage explants was measured by dimethylmethylene blue and Western blot analysis.
Results
Aggrecanase activity toward aggrecan was observed in all conditions, but it was directed toward the TEGE↓ARGS interglobular domain (IGD) site only when cartilage was coincubated with SJC or TNF-α. Matrix metalloproteinase (MMP) activity at the aggrecan IGD site (IPES↓FFGV) was not detected when cartilage was exposed to TNF-α (up to 6 days), but it was in all other conditions. Compared with when bovine cartilage was left untreated or subjected to mechanical injury alone, additional aggrecan fragment types were released into medium and proteolysis of aggrecan started at an earlier time when SJC was present.
Conclusions
Indicative of different proteolytic pathways for aggrecan degradation, the SJC increases both aggrecanase and MMP activity toward aggrecan, whereas TNF-α inhibits MMP activity against the IGD of aggrecan.National Institutes of Health (U.S.) (AR060331
Fluorescence optical imaging for treatment monitoring in patients with early and active rheumatoid arthritis in a 1-year follow-up period
BACKGROUND:
Fluorescence optical imaging (FOI) enables visualization of inflammation in the hands in rheumatic joint diseases with currently a lack of long-term follow-up studies.
OBJECTIVE:
To investigate FOI for treatment monitoring in a homogenous cohort of patients with early (disease duration  3.2) RA over a period of 12 months.
METHODS:
Thirty-five RA patients (24 (68.6%) females, mean age 53.3 years (SD 13.6)) were investigated clinically by DAS28, tender joint count (TJC) and swollen joint count (SJC) and by FOI in phases 1-3 and PrimaVistaMode (PVM) before therapy change and after 12 months. The FOI activity score (FOIAS) was calculated based on individual joint scores from 0 to 3 in 30 joints per patient, adding up to a sum score (0-90).
RESULTS:
We found a statistically significant reduction of FOIAS in phase 1 from baseline (median 5.0, IQR 24.96) to follow-up (median 1.0, IQR 4.0) in all patients (p = 0.0045), both in responders and non-responders according to EULAR response criteria by DAS28. Statistically significant reductions over 12 months were found for median DAS28(ESR) 5.61 to 3.31, TJC 7.0 to 1.0, and SJC 5.0 to 1.0 (each p <  0.001). No statistically significant correlations were detected between the FOIAS change in phase 1 and DAS28(ESR), TJC, or SJC. Correlations between the other phases and clinical outcomes were weak to moderate.
CONCLUSION:
Reduced early enhancement in FOI phase 1 can be observed in clinically responding and non-responding early RA patients under treatment. Regarding potential marker performance, FOI probably shows a reduction of inflammation more objectively
MAINTAINING THE ILLUSION OF DEMOCRACY: POLICY-MAKING AND ABORIGINAL EDUCATION IN CANADA, 1946-1948 1
Following the 1949 recommendations of the Joint Committee of the Senate and House of Commons (SJC), the Canadian government shifted away from a policy of segregated to integrated schooling for Aboriginal children. This paper examines the minutes and proceedings of the SJC. Fewer than 10% of the briefs presented to the SJC called for integration indicating that government’s policy shift was less reflective of the needs of the citizens who addressed the SJC than of government ―insiders‖ who had first promoted integration in the early 1940s. Nevertheless, the SJC’s open proceedings helped government to maintain the illusion of democratic processes
How We Do It in Massachusetts: An Overview of How the Massachusetts Supreme Judicial Court Has Interpreted Its State Constitution to Address Contemporary Legal Issues
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