18,536 research outputs found
Collaborative signal and information processing for target detection with heterogeneous sensor networks
In this paper, an approach for target detection and acquisition with heterogeneous sensor networks through strategic resource allocation and coordination is presented. Based on sensor management and collaborative signal and information processing, low-capacity low-cost sensors are strategically deployed to guide and cue scarce high performance sensors in the network to improve the data quality, with which the mission is eventually completed more efficiently with lower cost. We focus on the problem of designing such a network system in which issues of resource selection and allocation, system behaviour and capacity, target behaviour and patterns, the environment, and multiple constraints such as the cost must be addressed simultaneously. Simulation results offer significant insight into sensor selection and network operation, and demonstrate the great benefits introduced by guided search in an application of hunting down and capturing hostile vehicles on the battlefield
Cloudbus Toolkit for Market-Oriented Cloud Computing
This keynote paper: (1) presents the 21st century vision of computing and
identifies various IT paradigms promising to deliver computing as a utility;
(2) defines the architecture for creating market-oriented Clouds and computing
atmosphere by leveraging technologies such as virtual machines; (3) provides
thoughts on market-based resource management strategies that encompass both
customer-driven service management and computational risk management to sustain
SLA-oriented resource allocation; (4) presents the work carried out as part of
our new Cloud Computing initiative, called Cloudbus: (i) Aneka, a Platform as a
Service software system containing SDK (Software Development Kit) for
construction of Cloud applications and deployment on private or public Clouds,
in addition to supporting market-oriented resource management; (ii)
internetworking of Clouds for dynamic creation of federated computing
environments for scaling of elastic applications; (iii) creation of 3rd party
Cloud brokering services for building content delivery networks and e-Science
applications and their deployment on capabilities of IaaS providers such as
Amazon along with Grid mashups; (iv) CloudSim supporting modelling and
simulation of Clouds for performance studies; (v) Energy Efficient Resource
Allocation Mechanisms and Techniques for creation and management of Green
Clouds; and (vi) pathways for future research.Comment: 21 pages, 6 figures, 2 tables, Conference pape
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
Beyond sample curation and basic pathologic characterization, the digitized H&E-stained images
of TCGA samples remain underutilized. To highlight this resource, we present mappings of tumorinfiltrating lymphocytes (TILs) based on H&E images from 13 TCGA tumor types. These TIL
maps are derived through computational staining using a convolutional neural network trained to
classify patches of images. Affinity propagation revealed local spatial structure in TIL patterns and
correlation with overall survival. TIL map structural patterns were grouped using standard
histopathological parameters. These patterns are enriched in particular T cell subpopulations
derived from molecular measures. TIL densities and spatial structure were differentially enriched
among tumor types, immune subtypes, and tumor molecular subtypes, implying that spatial
infiltrate state could reflect particular tumor cell aberration states. Obtaining spatial lymphocytic
patterns linked to the rich genomic characterization of TCGA samples demonstrates one use for
the TCGA image archives with insights into the tumor-immune microenvironment
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