45,293 research outputs found
Data access and integration in the ISPIDER proteomics grid
Grid computing has great potential for supporting the integration of complex, fast changing biological data repositories to enable distributed data analysis. One scenario where Grid computing has such potential is provided by proteomics resources which are rapidly being developed with the emergence of affordable, reliable methods to study the proteome. The protein identifications arising from these methods derive from multiple repositories which need to be integrated to enable uniform access to them. A number of technologies exist which enable these resources to be accessed in a Grid environment, but the independent development of these resources means that significant data integration challenges, such as heterogeneity and schema evolution, have to be met. This paper presents an architecture which supports the combined use of Grid data access (OGSA-DAI), Grid distributed querying (OGSA-DQP) and data integration (AutoMed) software tools to support distributed data analysis. We discuss the application of this architecture for the integration of several autonomous proteomics data resources
Differentially Private Convex Optimization with Piecewise Affine Objectives
Differential privacy is a recently proposed notion of privacy that provides
strong privacy guarantees without any assumptions on the adversary. The paper
studies the problem of computing a differentially private solution to convex
optimization problems whose objective function is piecewise affine. Such
problem is motivated by applications in which the affine functions that define
the objective function contain sensitive user information. We propose several
privacy preserving mechanisms and provide analysis on the trade-offs between
optimality and the level of privacy for these mechanisms. Numerical experiments
are also presented to evaluate their performance in practice
Web and Semantic Web Query Languages
A number of techniques have been developed to facilitate
powerful data retrieval on the Web and Semantic Web. Three categories
of Web query languages can be distinguished, according to the format
of the data they can retrieve: XML, RDF and Topic Maps. This article
introduces the spectrum of languages falling into these categories
and summarises their salient aspects. The languages are introduced using
common sample data and query types. Key aspects of the query
languages considered are stressed in a conclusion
Reasoning & Querying – State of the Art
Various query languages for Web and Semantic Web data, both for practical use and as an area of research in the scientific community, have emerged in recent years. At the same time, the broad adoption of the internet where keyword search is used in many applications, e.g. search engines, has familiarized casual users with using keyword queries to retrieve information on the internet. Unlike this easy-to-use querying, traditional query languages require knowledge of the language itself as well as of the data to be queried. Keyword-based query languages for XML and RDF bridge the gap between the two, aiming at enabling simple querying of semi-structured data, which is relevant e.g. in the context of the emerging Semantic Web. This article presents an overview of the field of keyword querying for XML and RDF
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