Improving Knowledge Retrieval in Digital Libraries Applying Intelligent Techniques

Nowadays an enormous quantity of heterogeneous and distributed information is stored in the digital University. Exploring online collections to find knowledge relevant to a user’s interests is a challenging work. The artificial intelligence and Semantic Web provide a common framework that allows knowledge to be shared and reused in an efficient way. In this work we propose a comprehensive approach for discovering E-learning objects in large digital collections based on analysis of recorded semantic metadata in those objects and the application of expert system technologies. We have used Case Based-Reasoning methodology to develop a prototype for supporting efficient retrieval knowledge from online repositories. We suggest a conceptual architecture for a semantic search engine. OntoUS is a collaborative effort that proposes a new form of interaction between users and digital libraries, where the latter are adapted to users and their surroundings

A Clinical Prognostic Framework for Classifying Severe Liver Disorders (SLDs) and Lungs’ Vulnerability to Virus

Most severe liver diseases (SLDs) are attributed to increased risk for cancer, and cirrhosis, through which the manifestation of fibrotic tissues and scars tends to affect liver function The role of liver is indispensable, as inner organ performing services that ranges from metabolism, immune guide, energy producer and digestive aid, just to mention a few. Prevalence of classification problem and the need for automated prognosis is the continual drive to apply data mining techniques and/or machine learning algorithms in medical diagnosis and clinical support systems. Computational scientists and researchers in the field of artificial intelligence have recorded notable efforts with existing methods/models for diagnosis or prognosis, yet their effectiveness and functional performance is not without drawback due to ambiguity of medical information and selected features in patients’ data to tell the future course. In this paper, a novel hybridized machine learning model was provided (Fuzzy c-BC) for clinical classification of Severe Liver Disorders (SLDs) and to determine Lungs Vulnerability (LV) to virus; by incorporating individual strength of fuzzy cluster means (FCM) and naive Bayes classifier (NBC) for projecting future course of every categorized liver disease (LD) and its implication to aggravate lungs infection if preventive measures are not taken in timely manner

A case-based reasoning framework for prediction of stroke

© Springer Nature Singapore Pte Ltd. 2018. Case-based reasoning (CBR) has been a popular method in health care sector from the last two decades. It is used for analysis, prediction, diagnosis and recommending treatment for patients. This research purposes a conceptual CBR framework for stroke disease prediction that uses previous case-based knowledge. The outcomes of this approach not only assist in stroke disease decision-making, but also will be very useful for prevention and early treatment of patients

A novel combination of Cased-Based Reasoning and Multi Criteria Decision Making approach to radiotherapy dose planning

In this thesis, a set of novel approaches has been developed by integration of Cased-Based Reasoning (CBR) and Multi-Criteria Decision Making (MCDM) techniques. Its purpose is to design a support system to assist oncologists with decision making about the dose planning for radiotherapy treatment with a focus on radiotherapy for prostate cancer. CBR, an artificial intelligence approach, is a general paradigm to reasoning from past experiences. It retrieves previous cases similar to a new case and exploits the successful past solutions to provide a suggested solution for the new case. The case pool used in this research is a dataset consisting of features and details related to successfully treated patients in Nottingham University Hospital. In a typical run of prostate cancer radiotherapy simple CBR, a new case is selected and thereafter based on the features available at our data set the most similar case to the new case is obtained and its solution is prescribed to the new case. However, there are a number of deficiencies associated with this approach. Firstly, in a real-life scenario, the medical team considers multiple factors rather than just the similarity between two cases and not always the most similar case provides with the most appropriate solution. Thus, in this thesis, the cases with high similarity to a new case have been evaluated with the application of the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). This approach takes into account multiple criteria besides similarity to prescribe a final solution. Moreover, the obtained dose plans were optimised through a Goal Programming mathematical model to improve the results. By incorporating oncologists’ experiences about violating the conventionally available dose limits a system was devised to manage the trade-off between treatment risk for sensitive organs and necessary actions to effectively eradicate cancer cells. Additionally, the success rate of the treatment, the 2-years cancer free possibility, has a vital role in the efficiency of the prescribed solutions. To consider the success rate, as well as uncertainty involved in human judgment about the values of different features of radiotherapy Data Envelopment Analysis (DEA) based on grey numbers, was used to assess the efficiency of different treatment plans on an input and output based approach. In order to deal with limitations involved in DEA regarding the number of inputs and outputs, we presented an approach for Factor Analysis based on Principal Components to utilize the grey numbers. Finally, to improve the CBR base of the system, we applied Grey Relational Analysis and Gaussian distant based CBR along with features weight selection through Genetic Algorithm to better handle the non-linearity exists within the problem features and the high number of features. Finally, the efficiency of each system has been validated through leave-one-out strategy and the real dataset. The results demonstrated the efficiency of the proposed approaches and capability of the system to assist the medical planning team. Furthermore, the integrated approaches developed within this thesis can be also applied to solve other real-life problems in various domains other than healthcare such as supply chain management, manufacturing, business success prediction and performance evaluation

Addressing trust and mutability issues in XAI utilising case based reasoning.

Explainable AI (XAI) research is required to ensure that explanations are human readable and understandable. The present XAI approaches are useful for observing and comprehending some of the most important underlying properties of any Black-box AI model. However, when it comes to pushing them into production, certain critical concerns may arise: (1) How can end-users rely on the output of an XAI platform and trust the system? (2) How can end-users customise the platform's output depending on their own preferences In this project, we will explore how to address these concerns by utilising Cased-based Reasoning. Accordingly, we propose to exploit the neighbourhood to improve end-user trust by offering similar cases and confidence scores and using different retrieval strategies to address end-user preferences. Additionally, this project will also look at how to leverage Conversational AI and Natural Language Generation approaches to improve the interactive and engaging user experience with example-based XAI systems

Interpretable Medical Diagnostics with Structured Data Extraction by Large Language Models

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large language models (LLMs) which excel at textual tasks, are probably not the best tool for modeling tabular data. Therefore, we propose a novel, simple, and effective methodology for extracting structured tabular data from textual medical reports, called TEMED-LLM. Drawing upon the reasoning capabilities of LLMs, TEMED-LLM goes beyond traditional extraction techniques, accurately inferring tabular features, even when their names are not explicitly mentioned in the text. This is achieved by combining domain-specific reasoning guidelines with a proposed data validation and reasoning correction feedback loop. By applying interpretable ML models such as decision trees and logistic regression over the extracted and validated data, we obtain end-to-end interpretable predictions. We demonstrate that our approach significantly outperforms state-of-the-art text classification models in medical diagnostics. Given its predictive performance, simplicity, and interpretability, TEMED-LLM underscores the potential of leveraging LLMs to improve the performance and trustworthiness of ML models in medical applications