On the uniform one-dimensional fragment

The uniform one-dimensional fragment of first-order logic, U1, is a recently introduced formalism that extends two-variable logic in a natural way to contexts with relations of all arities. We survey properties of U1 and investigate its relationship to description logics designed to accommodate higher arity relations, with particular attention given to DLR_reg. We also define a description logic version of a variant of U1 and prove a range of new results concerning the expressivity of U1 and related logics

Categorical Ontology of Complex Systems, Meta-Systems and Theory of Levels: The Emergence of Life, Human Consciousness and Society

Single cell interactomics in simpler organisms, as well as somatic cell interactomics in multicellular organisms, involve biomolecular interactions in complex signalling pathways that were recently represented in modular terms by quantum automata with ‘reversible behavior’ representing normal cell cycling and division. Other implications of such quantum automata, modular modeling of signaling pathways and cell differentiation during development are in the fields of neural plasticity and brain development leading to quantum-weave dynamic patterns and specific molecular processes underlying extensive memory, learning, anticipation mechanisms and the emergence of human consciousness during the early brain development in children. Cell interactomics is here represented for the first time as a mixture of ‘classical’ states that determine molecular dynamics subject to Boltzmann statistics and ‘steady-state’, metabolic (multi-stable) manifolds, together with ‘configuration’ spaces of metastable quantum states emerging from complex quantum dynamics of interacting networks of biomolecules, such as proteins and nucleic acids that are now collectively defined as quantum interactomics. On the other hand, the time dependent evolution over several generations of cancer cells --that are generally known to undergo frequent and extensive genetic mutations and, indeed, suffer genomic transformations at the chromosome level (such as extensive chromosomal aberrations found in many colon cancers)-- cannot be correctly represented in the ‘standard’ terms of quantum automaton modules, as the normal somatic cells can. This significant difference at the cancer cell genomic level is therefore reflected in major changes in cancer cell interactomics often from one cancer cell ‘cycle’ to the next, and thus it requires substantial changes in the modeling strategies, mathematical tools and experimental designs aimed at understanding cancer mechanisms. Novel solutions to this important problem in carcinogenesis are proposed and experimental validation procedures are suggested. From a medical research and clinical standpoint, this approach has important consequences for addressing and preventing the development of cancer resistance to medical therapy in ongoing clinical trials involving stage III cancer patients, as well as improving the designs of future clinical trials for cancer treatments.\ud \ud \ud KEYWORDS: Emergence of Life and Human Consciousness;\ud Proteomics; Artificial Intelligence; Complex Systems Dynamics; Quantum Automata models and Quantum Interactomics; quantum-weave dynamic patterns underlying human consciousness; specific molecular processes underlying extensive memory, learning, anticipation mechanisms and human consciousness; emergence of human consciousness during the early brain development in children; Cancer cell ‘cycling’; interacting networks of proteins and nucleic acids; genetic mutations and chromosomal aberrations in cancers, such as colon cancer; development of cancer resistance to therapy; ongoing clinical trials involving stage III cancer patients’ possible improvements of the designs for future clinical trials and cancer treatments. \ud \u

Cut-free Calculi and Relational Semantics for Temporal STIT Logics

We present cut-free labelled sequent calculi for a central formalism in logics of agency: STIT logics with temporal operators. These include sequent systems for Ldm , Tstit and Xstit. All calculi presented possess essential structural properties such as contraction- and cut-admissibility. The labelled calculi G3Ldm and G3Tstit are shown sound and complete relative to irreflexive temporal frames. Additionally, we extend current results by showing that also Xstit can be characterized through relational frames, omitting the use of BT+AC frames

Querying the Guarded Fragment

Evaluating a Boolean conjunctive query Q against a guarded first-order theory F is equivalent to checking whether "F and not Q" is unsatisfiable. This problem is relevant to the areas of database theory and description logic. Since Q may not be guarded, well known results about the decidability, complexity, and finite-model property of the guarded fragment do not obviously carry over to conjunctive query answering over guarded theories, and had been left open in general. By investigating finite guarded bisimilar covers of hypergraphs and relational structures, and by substantially generalising Rosati's finite chase, we prove for guarded theories F and (unions of) conjunctive queries Q that (i) Q is true in each model of F iff Q is true in each finite model of F and (ii) determining whether F implies Q is 2EXPTIME-complete. We further show the following results: (iii) the existence of polynomial-size conformal covers of arbitrary hypergraphs; (iv) a new proof of the finite model property of the clique-guarded fragment; (v) the small model property of the guarded fragment with optimal bounds; (vi) a polynomial-time solution to the canonisation problem modulo guarded bisimulation, which yields (vii) a capturing result for guarded bisimulation invariant PTIME.Comment: This is an improved and extended version of the paper of the same title presented at LICS 201

Łukasiewicz-Moisil Many-Valued Logic Algebra of Highly-Complex Systems

A novel approach to self-organizing, highly-complex systems (HCS), such as living organisms and artificial intelligent systems (AIs), is presented which is relevant to Cognition, Medical Bioinformatics and Computational Neuroscience. Quantum Automata (QAs) were defined in our previous work as generalized, probabilistic automata with quantum state spaces (Baianu, 1971). Their next-state functions operate through transitions between quantum states defined by the quantum equations of motion in the Schroedinger representation, with both initial and boundary conditions in space-time. Such quantum automata operate with a quantum logic, or Q-logic, significantly different from either Boolean or Łukasiewicz many-valued logic. A new theorem is proposed which states that the category of quantum automata and automata--homomorphisms has both limits and colimits. Therefore, both categories of quantum automata and classical automata (sequential machines) are bicomplete. A second new theorem establishes that the standard automata category is a subcategory of the quantum automata category. The quantum automata category has a faithful representation in the category of Generalized (M,R)--Systems which are open, dynamic biosystem networks with defined biological relations that represent physiological functions of primordial organisms, single cells and higher organisms

A logic with temporally accessible iteration

Deficiency in expressive power of the first-order logic has led to developing its numerous extensions by fixed point operators, such as Least Fixed-Point (LFP), inflationary fixed-point (IFP), partial fixed-point (PFP), etc. These logics have been extensively studied in finite model theory, database theory, descriptive complexity. In this paper we introduce unifying framework, the logic with iteration operator, in which iteration steps may be accessed by temporal logic formulae. We show that proposed logic FO+TAI subsumes all mentioned fixed point extensions as well as many other fixed point logics as natural fragments. On the other hand we show that over finite structures FO+TAI is no more expressive than FO+PFP. Further we show that adding the same machinery to the logic of monotone inductions (FO+LFP) does not increase its expressive power either

Logics of Finite Hankel Rank

We discuss the Feferman-Vaught Theorem in the setting of abstract model theory for finite structures. We look at sum-like and product-like binary operations on finite structures and their Hankel matrices. We show the connection between Hankel matrices and the Feferman-Vaught Theorem. The largest logic known to satisfy a Feferman-Vaught Theorem for product-like operations is CFOL, first order logic with modular counting quantifiers. For sum-like operations it is CMSOL, the corresponding monadic second order logic. We discuss whether there are maximal logics satisfying Feferman-Vaught Theorems for finite structures.Comment: Appeared in YuriFest 2015, held in honor of Yuri Gurevich's 75th birthday. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-23534-9_1

Relation-changing modal operators

We study dynamic modal operators that can change the accessibility relation of a model during the evaluation of a formula. In particular, we extend the basic modal language with modalities that are able to delete, add or swap an edge between pairs of elements of the domain. We define a generic framework to characterize this kind of operations. First, we investigate relation-changing modal logics as fragments of classical logics. Then, we use the new framework to get a suitable notion of bisimulation for the logics introduced, and we investigate their expressive power. Finally, we show that the complexity of the model checking problem for the particular operators introduced is PSpace-complete, and we study two subproblems of model checking: formula complexity and program complexity.Fil: Areces, Carlos Eduardo. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fervari, Raul Alberto. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hoffmann, Guillaume Emmanuel. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Randomisation and Derandomisation in Descriptive Complexity Theory

We study probabilistic complexity classes and questions of derandomisation from a logical point of view. For each logic L we introduce a new logic BPL, bounded error probabilistic L, which is defined from L in a similar way as the complexity class BPP, bounded error probabilistic polynomial time, is defined from PTIME. Our main focus lies on questions of derandomisation, and we prove that there is a query which is definable in BPFO, the probabilistic version of first-order logic, but not in Cinf, finite variable infinitary logic with counting. This implies that many of the standard logics of finite model theory, like transitive closure logic and fixed-point logic, both with and without counting, cannot be derandomised. Similarly, we present a query on ordered structures which is definable in BPFO but not in monadic second-order logic, and a query on additive structures which is definable in BPFO but not in FO. The latter of these queries shows that certain uniform variants of AC0 (bounded-depth polynomial sized circuits) cannot be derandomised. These results are in contrast to the general belief that most standard complexity classes can be derandomised. Finally, we note that BPIFP+C, the probabilistic version of fixed-point logic with counting, captures the complexity class BPP, even on unordered structures