Challenges in the Analysis of Mass-Throughput Data: A Technical Commentary from the Statistical Machine Learning Perspective

Sound data analysis is critical to the success of modern molecular medicine research that involves collection and interpretation of mass-throughput data. The novel nature and high-dimensionality in such datasets pose a series of nontrivial data analysis problems. This technical commentary discusses the problems of over-fitting, error estimation, curse of dimensionality, causal versus predictive modeling, integration of heterogeneous types of data, and lack of standard protocols for data analysis. We attempt to shed light on the nature and causes of these problems and to outline viable methodological approaches to overcome them

Electrical and Computer Engineering Annual Report 2018

Welcome New President and Dean Faculty Directory Faculty Highlights Exciting Challenges for Expert Teacher Mobility Research: Sumit Paudyal Mobility Research: Chee-Wooi Ten Mobility Research: Bruce Mork Faculty Profile and Department Award Faculty Publications Staff Profile and Directory Graduate Student Awards and Degrees Student Highlights Senior Design Enterprise Enterprise and Undergraduate Student Awards ECE Academy Class of 2018 External Advisory Committee Contracts and Grants Department Statisticshttps://digitalcommons.mtu.edu/ece-annualreports/1000/thumbnail.jp

A Survey of Learning in Multiagent Environments: Dealing with Non-Stationarity

The key challenge in multiagent learning is learning a best response to the behaviour of other agents, which may be non-stationary: if the other agents adapt their strategy as well, the learning target moves. Disparate streams of research have approached non-stationarity from several angles, which make a variety of implicit assumptions that make it hard to keep an overview of the state of the art and to validate the innovation and significance of new works. This survey presents a coherent overview of work that addresses opponent-induced non-stationarity with tools from game theory, reinforcement learning and multi-armed bandits. Further, we reflect on the principle approaches how algorithms model and cope with this non-stationarity, arriving at a new framework and five categories (in increasing order of sophistication): ignore, forget, respond to target models, learn models, and theory of mind. A wide range of state-of-the-art algorithms is classified into a taxonomy, using these categories and key characteristics of the environment (e.g., observability) and adaptation behaviour of the opponents (e.g., smooth, abrupt). To clarify even further we present illustrative variations of one domain, contrasting the strengths and limitations of each category. Finally, we discuss in which environments the different approaches yield most merit, and point to promising avenues of future research

Santa Clara Magazine, Volume 38 Number 3, Summer 1996

6 - THE BEATEN TRACK SCU Psychologist Stephanie Etukudo and Senior Lecturer in English Jeffrey Zorn debate whether ability groupings serve students\u27 best interests. 12 - WHAT WOULD SOLOMON SAY? Adoptions gone awry trigger controversy over how to safeguard the rights of parents while protecting the welfare of the child. By Elizabeth Fernandez \u2779 18 - A THIRST FOR HEALING A pilgrim to Lourdes finds that the cures offered by the blessed waters can be mostly invisible. By Dee Danna \u2768 (MBA \u2772) 24 - THE FLOWERING OF SANTA CLARA UNIVERSITY For more than a century, the Mission Gardens have offered spiritual and aesthetic refreshment. By Miriam Schulman 30 - SECOND-PLACE TROPHIES RARELY GET POLISHED Just one run short of the national championship, the 1962 Bronco baseball team was the finest ever fielded by the University. By Dan Peterson \u2797https://scholarcommons.scu.edu/sc_mag/1061/thumbnail.jp

A Survey of Learning in Multiagent Environments: Dealing with Non-Stationarity

The key challenge in multiagent learning is learning a best response to the behaviour of other agents, which may be non-stationary: if the other agents adapt their strategy as well, the learning target moves. Disparate streams of research have approached non-stationarity from several angles, which make a variety of implicit assumptions that make it hard to keep an overview of the state of the art and to validate the innovation and significance of new works. This survey presents a coherent overview of work that addresses opponent-induced non-stationarity with tools from game theory, reinforcement learning and multi-armed bandits. Further, we reflect on the principle approaches how algorithms model and cope with this non-stationarity, arriving at a new framework and five categories (in increasing order of sophistication): ignore, forget, respond to target models, learn models, and theory of mind. A wide range of state-of-the-art algorithms is classified into a taxonomy, using these categories and key characteristics of the environment (e.g., observability) and adaptation behaviour of the opponents (e.g., smooth, abrupt). To clarify even further we present illustrative variations of one domain, contrasting the strengths and limitations of each category. Finally, we discuss in which environments the different approaches yield most merit, and point to promising avenues of future research

Multi-Robot Systems: Challenges, Trends and Applications

This book is a printed edition of the Special Issue entitled “Multi-Robot Systems: Challenges, Trends, and Applications” that was published in Applied Sciences. This Special Issue collected seventeen high-quality papers that discuss the main challenges of multi-robot systems, present the trends to address these issues, and report various relevant applications. Some of the topics addressed by these papers are robot swarms, mission planning, robot teaming, machine learning, immersive technologies, search and rescue, and social robotics

Robust distributed planning strategies for autonomous multi-agent teams

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2012.Cataloged from department-submitted PDF version of thesis. This electronic version was submitted and approved by the author's academic department as part of an electronic thesis pilot project. The certified thesis is available in the Institute Archives and Special Collections.Includes bibliographical references (p. 225-244).The increased use of autonomous robotic agents, such as unmanned aerial vehicles (UAVs) and ground rovers, for complex missions has motivated the development of autonomous task allocation and planning methods that ensure spatial and temporal coordination for teams of cooperating agents. The basic problem can be formulated as a combinatorial optimization (mixed-integer program) involving nonlinear and time-varying system dynamics. For most problems of interest, optimal solution methods are computationally intractable (NP-Hard), and centralized planning approaches, which usually require high bandwidth connections with a ground station (e.g. to transmit received sensor data, and to dispense agent plans), are resource intensive and react slowly to local changes in dynamic environments. Distributed approximate algorithms, where agents plan individually and coordinate with each other locally through consensus protocols, can alleviate many of these issues and have been successfully used to develop real-time conflict-free solutions for heterogeneous networked teams. An important issue associated with autonomous planning is that many of the algorithms rely on underlying system models and parameters which are often subject to uncertainty. This uncertainty can result from many sources including: inaccurate modeling due to simplifications, assumptions, and/or parameter errors; fundamentally nondeterministic processes (e.g. sensor readings, stochastic dynamics); and dynamic local information changes. As discrepancies between the planner models and the actual system dynamics increase, mission performance typically degrades. The impact of these discrepancies on the overall quality of the plan is usually hard to quantify in advance due to nonlinear effects, coupling between tasks and agents, and interdependencies between system constraints. However, if uncertainty models of planning parameters are available, they can be leveraged to create robust plans that explicitly hedge against the inherent uncertainty given allowable risk thresholds. This thesis presents real-time robust distributed planning strategies that can be used to plan for multi-agent networked teams operating in stochastic and dynamic environments. One class of distributed combinatorial planning algorithms involves using auction algorithms augmented with consensus protocols to allocate tasks amongst a team of agents while resolving conflicting assignments locally between the agents. A particular algorithm in this class is the Consensus-Based Bundle Algorithm (CBBA), a distributed auction protocol that guarantees conflict-free solutions despite inconsistencies in situational awareness across the team. CBBA runs in polynomial time, demonstrating good scalability with increasing numbers of agents and tasks. This thesis builds upon the CBBA framework to address many realistic considerations associated with planning for networked teams, including time-critical mission constraints, limited communication between agents, and stochastic operating environments. A particular focus of this work is a robust extension to CBBA that handles distributed planning in stochastic environments given probabilistic parameter models and different stochastic metrics. The Robust CBBA algorithm proposed in this thesis provides a distributed real-time framework which can leverage different stochastic metrics to hedge against parameter uncertainty. In mission scenarios where low probability of failure is required, a chance-constrained stochastic metric can be used to provide probabilistic guarantees on achievable mission performance given allowable risk thresholds. This thesis proposes a distributed chance-constrained approximation that can be used within the Robust CBBA framework, and derives constraints on individual risk allocations to guarantee equivalence between the centralized chance-constrained optimization and the distributed approximation. Different risk allocation strategies for homogeneous and heterogeneous teams are proposed that approximate the agent and mission score distributions a priori, and results are provided showing improved performance in time-critical mission scenarios given allowable risk thresholds.by Sameera S. Ponda.Ph.D