Integrated Application and Improvement of Selection Method of Storage Sales Industry

In recent years, in order to adapt to the rapid development of the warehouse-storage sales industry and to solve the problems of location cost and efficiency and optimization of the methods of the new retail store, we have integrated and innovated the barycenter method and grey correlation method, and analyzed the grey correlation method with the weight obtained by the comprehensive analysis. In order to achieve the optimal cost effect, we choose the optimal solution from several alternative address schemes. It is found that using the integrated method as the reference standard for the location calculation of Warehouse Logistics Enterprises under the new retail background is helpful to improve the accuracy rate, and reduce the defects and defects caused by the independent use of the various methods, and adapt to the more practical and concrete conditions of the location selection of warehouse storage enterprises. At the same time, it is also an innovative attempt to cross discrete and continuous boundaries

Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictions

BACKGROUND: Understanding the dynamics of biological processes can substantially be supported by computational models in the form of nonlinear ordinary differential equations (ODE). Typically, this model class contains many unknown parameters, which are estimated from inadequate and noisy data. Depending on the ODE structure, predictions based on unmeasured states and associated parameters are highly uncertain, even undetermined. For given data, profile likelihood analysis has been proven to be one of the most practically relevant approaches for analyzing the identifiability of an ODE structure, and thus model predictions. In case of highly uncertain or non-identifiable parameters, rational experimental design based on various approaches has shown to significantly reduce parameter uncertainties with minimal amount of effort. RESULTS: In this work we illustrate how to use profile likelihood samples for quantifying the individual contribution of parameter uncertainty to prediction uncertainty. For the uncertainty quantification we introduce the profile likelihood sensitivity (PLS) index. Additionally, for the case of several uncertain parameters, we introduce the PLS entropy to quantify individual contributions to the overall prediction uncertainty. We show how to use these two criteria as an experimental design objective for selecting new, informative readouts in combination with intervention site identification. The characteristics of the proposed multi-criterion objective are illustrated with an in silico example. We further illustrate how an existing practically non-identifiable model for the chlorophyll fluorescence induction in a photosynthetic organism, D. salina, can be rendered identifiable by additional experiments with new readouts. CONCLUSIONS: Having data and profile likelihood samples at hand, the here proposed uncertainty quantification based on prediction samples from the profile likelihood provides a simple way for determining individual contributions of parameter uncertainties to uncertainties in model predictions. The uncertainty quantification of specific model predictions allows identifying regions, where model predictions have to be considered with care. Such uncertain regions can be used for a rational experimental design to render initially highly uncertain model predictions into certainty. Finally, our uncertainty quantification directly accounts for parameter interdependencies and parameter sensitivities of the specific prediction. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-014-0436-5) contains supplementary material, which is available to authorized users

Full Proceedings, 2018

Full conference proceedings for the 2018 International Building Physics Association Conference hosted at Syracuse University