Effect of increased left ventricle mass on ischemia assessment in electrocardiographic signals: rabbit isolated heart study

Detailed quantitative analysis of the effect of left ventricle (LV) hypertrophy on myocardial ischemia manifestation in ECG is still missing. The associations between both phenomena can be studied in animal models. In this study, rabbit isolated hearts with spontaneously increased LV mass were used to evaluate the effect of such LV alteration on ischemia detection criteria and performance. Electrophysiological effects of increased LV mass were evaluated on sixteen New Zealand rabbit isolated hearts under non-ischemic and ischemic conditions by analysis of various electrogram (EG) parameters. To reveal hearts with increased LV mass, LV weight/heart weight ratio was proposed. Standard paired and unpaired statistical tests and receiver operating characteristics analysis were used to compare data derived from different groups of animals, monitor EG parameters during global ischemia and evaluate their ability to discriminate between unchanged and increased LV as well as non-ischemic and ischemic state. Successful evaluation of both increased LV mass and ischemia is lead-dependent. Particularly, maximal deviation of QRS and area under QRS associated with anterolateral heart wall respond significantly to even early phase (the 1st-3rd min) of ischemia. Besides ischemia, these parameters reflect increased LV mass as well (with sensitivity reaching approx. 80%). However, the sensitivity of the parameters to both phenomena may lead to misinterpretations, when inappropriate criteria for ischemia detection are selected. Particularly, use of cut-off-based criteria defined from control group for ischemia detection in hearts with increased LV mass may result in dramatic reduction (approx. 15%) of detection specificity due to increased number of false positives. Nevertheless, criteria adjusted to particular experimental group allow achieving ischemia detection sensitivity of 89–100% and specificity of 94–100%, respectively. It was shown that response of the heart to myocardial ischemia can be successfully evaluated only when taking into account heart-related factors (such as LV mass) and other methodological aspects (such as recording electrodes position, selected EG parameters, cut-off criteria, etc.). Results of this study might be helpful for developing new clinical diagnostic strategies in order to improve myocardial ischemia detection in patients with LV hypertrophy

A Novel Architecture of Software Testing based on SDN Hypervisor Technique for Big Data

There is a lack of network standard skills in present networking landscape. There is an increase in data plane granularity, data plane separation and simplifies the network devices, even networking industry has experienced a renewal with Software-Defined Networking (SDN). The device performance is improve by the linearly protocol by using SDN controller. The SDN-based software testing architecture is the basics of hypervisor approach. The application layer is initially combined with network updates, security and Quality of service. Software Defined Network (SDN) is a main feature. By using data plane communication protocol, the protocol communication is simplified. The physical switch controls the network data plane and virtual switch. The performance and efficiency are the accurate results that are achieved. Therefore, processing, storage, acquisition of big data and transmission are highly possible by SDN. The operation and design of SDN has big data impact. Hence, this method shows better results interms of accuracy, efficiency, computational time and security

A Systematic Review of the State of Cyber-Security in Water Systems

Critical infrastructure systems are evolving from isolated bespoke systems to those that use general-purpose computing hosts, IoT sensors, edge computing, wireless networks and artificial intelligence. Although this move improves sensing and control capacity and gives better integration with business requirements, it also increases the scope for attack from malicious entities that intend to conduct industrial espionage and sabotage against these systems. In this paper, we review the state of the cyber-security research that is focused on improving the security of the water supply and wastewater collection and treatment systems that form part of the critical national infrastructure. We cover the publication statistics of the research in this area, the aspects of security being addressed, and future work required to achieve better cyber-security for water systems

Automated Test Generation for REST APIs: No Time to Rest Yet

Modern web services routinely provide REST APIs for clients to access their functionality. These APIs present unique challenges and opportunities for automated testing, driving the recent development of many techniques and tools that generate test cases for API endpoints using various strategies. Understanding how these techniques compare to one another is difficult, as they have been evaluated on different benchmarks and using different metrics. To fill this gap, we performed an empirical study aimed to understand the landscape in automated testing of REST APIs and guide future research in this area. We first identified, through a systematic selection process, a set of 10 state-of-the-art REST API testing tools that included tools developed by both researchers and practitioners. We then applied these tools to a benchmark of 20 real-world open-source RESTful services and analyzed their performance in terms of code coverage achieved and unique failures triggered. This analysis allowed us to identify strengths, weaknesses, and limitations of the tools considered and of their underlying strategies, as well as implications of our findings for future research in this area.Comment: 13 pages, 6 figures, In Proceedings of the 31st ACM SIGSOFT International Symposium on Software Testing and Analysis (ISSTA) 202

iTrust News Certificate: A Blockchain-Based Solution for News Verification and Reputation Management

The proliferation of fake news and misinformation in the digital era poses a significant challenge to news organizations and content creators. In this paper, we intro-duce the iTrust News Certificate, the architecture of an online blockchain-based solution designed to combat fake news, enhance news verification, and maintain reputation within the media ecosystem. Unlike previous attempts, iTrust News Certificate focuses on us-er-friendly features while ensuring transparency and reliability. By leveraging blockchain technology, iTrust News Certificate establishes a decentralized and immutable ledger for storing news-related metadata. This ledger ensures the integrity and traceability of news articles, making it extremely difficult for malicious actors to tamper with or propagate false information

Cascading Failures Analysis Considering Extreme Virus Propagation of Cyber-Physical Systems in Smart Grids

Communication networks as smart infrastructure systems play an important role in smart girds to monitor, control, and manage the operation of electrical networks. However, due to the interdependencies between communication networks and electrical networks, once communication networks fail (or are attacked), the faults can be easily propagated to electrical networks which even lead to cascading blackout; therefore it is crucial to investigate the impacts of failures of communication networks on the operation of electrical networks. This paper focuses on cascading failures in interdependent systems from the perspective of cyber-physical security. In the interdependent fault propagation model, the complex network-based virus propagation model is used to describe virus infection in the scale-free and small-world topologically structured communication networks. Meanwhile, in the electrical network, dynamic power flow is employed to reproduce the behaviors of the electrical networks after a fault. In addition, two time windows, i.e., the virus infection cycle and the tripping time of overloaded branches, are considered to analyze the fault characteristics of both electrical branches and communication nodes along time under virus propagation. The proposed model is applied to the IEEE 118-bus system and the French grid coupled with different communication network structures. The results show that the scale-free communication network is more vulnerable to virus propagation in smart cyber-physical grids