7,660 research outputs found
Paying for Avoided Deforestation - Should We Do It?
Environmental Economics and Policy, Resource /Energy Economics and Policy, Q23, Q56, Q57,
Dynamic Interaction between Economic Indicators and SO2 Emission in U.S.
Environmental Kuznets Curve, Energy Use, Vector Autoregression, Historical Decomposition, Environmental Economics and Policy, International Relations/Trade, Resource /Energy Economics and Policy, Q43, Q52, Q56,
TO NEGOTIATE OR TO GAME THEORIZE: Negotiation vs. Game Theory Outcomes for Water Allocation Problems in the Kat Basin, South Africa
The 6th MEETING ON GAME THEORY AND PRACTICE Zaragoza, Spain 10-12 July 2006Negotiation, Role-playing game, Core, Nucleolus, Shapley value, Water allocation, Economic efficiency, Planning models, Resource /Energy Economics and Policy, C61, C71, C78, Q25, Q56, R14,
Intraindustry Trade and the Environment: Is There a Selection Effect?
Replaced with revised version of paper 08/06/10.Environment, Trade, Monopolistic Competition, Selection effect, Environmental quality, Panel data, OECD, Pollution, Environmental Economics and Policy, International Development, International Relations/Trade, Q56, Q51, Q53, Q58, F12, F18,
Probing for Binding Regions of the FtsZ Protein Surface through Site-Directed Insertions: Discovery of Fully Functional FtsZ-Fluorescent Proteins
FtsZ, a bacterial tubulin homologue, is a cytoskeletal protein that assembles into protofilaments that are one subunit thick. These protofilaments assemble further to form a âZ ringâ at the center of prokaryotic cells. The Z ring generates a constriction force on the inner membrane and also serves as a scaffold to recruit cell wall remodeling proteins for complete cell division in vivo. One model of the Z ring proposes that protofilaments associate via lateral bonds to form ribbons; however, lateral bonds are still only hypothetical. To explore potential lateral bonding sites, we probed the surface of Escherichia coli FtsZ by inserting either small peptides or whole fluorescent proteins (FPs). Among the four lateral surfaces on FtsZ protofilaments, we obtained inserts on the front and back surfaces that were functional for cell division. We concluded that these faces are not sites of essential interactions. Inserts at two sites, G124 and R174, located on the left and right surfaces, completely blocked function, and these sites were identified as possible sites for essential lateral interactions. However, the insert at R174 did not interfere with association of protofilaments into sheets and bundles in vitro. Another goal was to find a location within FtsZ that supported insertion of FP reporter proteins while allowing the FtsZ-FPs to function as the sole source of FtsZ. We discovered one internal site, G55-Q56, where several different FPs could be inserted without impairing function. These FtsZ-FPs may provide advances for imaging Z-ring structure by superresolution techniques. IMPORTANCE One model for the Z-ring structure proposes that protofilaments are assembled into ribbons by lateral bonds between FtsZ subunits. Our study excluded the involvement of the front and back faces of the protofilament in essential interactions in vivo but pointed to two potential lateral bond sites, on the right and left sides. We also identified an FtsZ loop where various fluorescent proteins could be inserted without blocking function; these FtsZ-FPs functioned as the sole source of FtsZ. This advance provides improved tools for all fluorescence imaging of the Z ring and may be especially important for superresolution imaging
Currents and Moduli in the (4,0) theory
We consider black strings in five dimensions and their description as a (4,0)
CFT. The CFT moduli space is described explicitly, including its subtle global
structure. BPS conditions and global symmetries determine the spectrum of
charged excitations, leading to an entropy formula for near-extreme black holes
in four dimensions with arbitrary charge vector. In the BPS limit, this formula
reduces to the quartic E(7,7) invariant. The prospects for a description of the
(4,0) theory as a solvable CFT are explored.Comment: 40 pages; v2: refs adde
Towards standard methods for benchmark quality ab initio thermochemistry --- W1 and W2 theory
Two new schemes for computing molecular total atomization energies (TAEs)
and/or heats of formation () of first-and second-row
compounds to very high accuracy are presented. The more affordable scheme, W1
(Weizmann-1) theory, yields a mean absolute error of 0.30 kcal/mol and includes
only a single, molecule-independent, empirical parameter. It requires CCSD
(coupled cluster with all single and double substitutions) calculations in
and basis sets, while CCSD(T) [i.e. CCSD with a
quasiperturbative treatment of connected triple excitations] calculations are
only required in and basis sets. On workstation computers and
using conventional coupled cluster algorithms, systems as large as benzene can
be treated, while larger systems are feasible using direct coupled cluster
methods. The more rigorous scheme, W2 (Weizmann-2) theory, contains no
empirical parameters at all and yields a mean absolute error of 0.23 kcal/mol,
which is lowered to 0.18 kcal/mol for molecules dominated by dynamical
correlation. It involves CCSD calculations in and basis sets
and CCSD(T) calculations in and basis sets. On workstation
computers, molecules with up to three heavy atoms can be treated using
conventional coupled cluster algorithms, while larger systems can still be
treated using a direct CCSD code. Both schemes include corrections for scalar
relativistic effects, which are found to be vital for accurate results on
second-row compounds.Comment: J. Chem. Phys., in press; text 30 pages RevTeX; tables 10 pages, HTML
and PostScript versions both included Reason for replacement: fixed typos in
Table II in proo
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