Non-invasive vascular assessment using photoplethysmography

Photoplethysmography (PPG) has become widely accepted as a valuable clinical tool for performing non-invasive biomedical monitoring. The dominant clinical application of PPG has been pulse oximetry, which uses spectral analysis of the peripheral blood supply to establish haemoglobin saturation. PPG has also found success in screening for venous dysfunction, though to a limited degree. Arterial Disease (AD) is a condition where blood flow in the arteries of the body is reduced,a condition known as ischaernia. Ischaernia can result in pain in the affected areas, such as chest pain for an ischearnic heart, but does not always produce symptoms. The most common form of AD is arteriosclerosis, which affects around 5% of the population over 50 years old. Arteriosclerosis, more commonly known as 'hardening of the arteries' is a condition that results in a gradual thickening, hardening and loss of elasticity in the walls of the arteries, reducing overall blood flow. This thesis investigates the possibility of employing PPG to perform vascular assessment, specifically arterial assessment, in two ways. PPG based perfusion monitoring may allow identification of ischaernia in the periphery. To further investigate this premise, prospective experimental trials are performed, firstly to assess the viability of PPG based perfusion monitoring and culminating in the development of a more objective method for determining ABPI using PPG based vascular assessment. A complex interaction between the heart and the connective vasculature, detected at the measuring site, generates the PPG signal. The haemodynamic properties of the vasculature will affect the shape of the PPG waveform, characterising the PPG signal with the properties of the intermediary vasculature. This thesis investigates the feasibility of deriving quantitative vascular parameters from the PPG signal. A quantitative approach allows direct identification of pathology, simplifying vascular assessment. Both forward and inverse models are developed in order to investigate this topic. Application of the models in prospective experimental trials with both normal subjects and subjects suffering PVD have shown encouraging results. It is concluded that the PPG signal contains information on the connective vasculature of the subject. PPG may be used to perform vascular assessment using either perfusion based techniques, where the magnitude of the PPG signal is of interest, or by directly assessing the connective vasculature using PPG, where the shape of the PPG signal is of interest. it is argued that PPG perfusion based techniques for performing the ABPI diagnosis protocol can offer greater sensitivity to the onset of PAD, compared to more conventional methods. It is speculated that the PPG based ABPI diagnosis protocol could provide enhanced PAD diagnosis, detecting the onset of the disease and allowing a treatmenpt lan to be formed soonert han was possible previously. The determination of quantitative vascular parameters using PPG shape could allow direct vascular diagnosis, reducing subjectivity due to interpretation. The prospective trials investigating PPG shape analysis concentrated on PVD diagnosis, but it is speculated that quantitative PPG shaped based vascular assessment could be a powerful tool in the diagnosis of many vascular based pathological conditions

1-D broadside-radiating leaky-wave antenna based on a numerically synthesized impedance surface

A newly-developed deterministic numerical technique for the automated design of metasurface antennas is applied here for the first time to the design of a 1-D printed Leaky-Wave Antenna (LWA) for broadside radiation. The surface impedance synthesis process does not require any a priori knowledge on the impedance pattern, and starts from a mask constraint on the desired far-field and practical bounds on the unit cell impedance values. The designed reactance surface for broadside radiation exhibits a non conventional patterning; this highlights the merit of using an automated design process for a design well known to be challenging for analytical methods. The antenna is physically implemented with an array of metal strips with varying gap widths and simulation results show very good agreement with the predicted performance

Beam scanning by liquid-crystal biasing in a modified SIW structure

A fixed-frequency beam-scanning 1D antenna based on Liquid Crystals (LCs) is designed for application in 2D scanning with lateral alignment. The 2D array environment imposes full decoupling of adjacent 1D antennas, which often conflicts with the LC requirement of DC biasing: the proposed design accommodates both. The LC medium is placed inside a Substrate Integrated Waveguide (SIW) modified to work as a Groove Gap Waveguide, with radiating slots etched on the upper broad wall, that radiates as a Leaky-Wave Antenna (LWA). This allows effective application of the DC bias voltage needed for tuning the LCs. At the same time, the RF field remains laterally confined, enabling the possibility to lay several antennas in parallel and achieve 2D beam scanning. The design is validated by simulation employing the actual properties of a commercial LC medium

Mobile and Wireless Communications

Mobile and Wireless Communications have been one of the major revolutions of the late twentieth century. We are witnessing a very fast growth in these technologies where mobile and wireless communications have become so ubiquitous in our society and indispensable for our daily lives. The relentless demand for higher data rates with better quality of services to comply with state-of-the art applications has revolutionized the wireless communication field and led to the emergence of new technologies such as Bluetooth, WiFi, Wimax, Ultra wideband, OFDMA. Moreover, the market tendency confirms that this revolution is not ready to stop in the foreseen future. Mobile and wireless communications applications cover diverse areas including entertainment, industrialist, biomedical, medicine, safety and security, and others, which definitely are improving our daily life. Wireless communication network is a multidisciplinary field addressing different aspects raging from theoretical analysis, system architecture design, and hardware and software implementations. While different new applications are requiring higher data rates and better quality of service and prolonging the mobile battery life, new development and advanced research studies and systems and circuits designs are necessary to keep pace with the market requirements. This book covers the most advanced research and development topics in mobile and wireless communication networks. It is divided into two parts with a total of thirty-four stand-alone chapters covering various areas of wireless communications of special topics including: physical layer and network layer, access methods and scheduling, techniques and technologies, antenna and amplifier design, integrated circuit design, applications and systems. These chapters present advanced novel and cutting-edge results and development related to wireless communication offering the readers the opportunity to enrich their knowledge in specific topics as well as to explore the whole field of rapidly emerging mobile and wireless networks. We hope that this book will be useful for students, researchers and practitioners in their research studies

Progress in general physics, plasma dynamics, communication sciences, and engineering Quarterly progress report no. 79, period ending 31 Aug. 1965

Physics, plasma dynamics, communication sciences, and engineerin

Cooperative Radio Communications for Green Smart Environments

The demand for mobile connectivity is continuously increasing, and by 2020 Mobile and Wireless Communications will serve not only very dense populations of mobile phones and nomadic computers, but also the expected multiplicity of devices and sensors located in machines, vehicles, health systems and city infrastructures. Future Mobile Networks are then faced with many new scenarios and use cases, which will load the networks with different data traffic patterns, in new or shared spectrum bands, creating new specific requirements. This book addresses both the techniques to model, analyse and optimise the radio links and transmission systems in such scenarios, together with the most advanced radio access, resource management and mobile networking technologies. This text summarises the work performed by more than 500 researchers from more than 120 institutions in Europe, America and Asia, from both academia and industries, within the framework of the COST IC1004 Action on "Cooperative Radio Communications for Green and Smart Environments". The book will have appeal to graduates and researchers in the Radio Communications area, and also to engineers working in the Wireless industry. Topics discussed in this book include: • Radio waves propagation phenomena in diverse urban, indoor, vehicular and body environments• Measurements, characterization, and modelling of radio channels beyond 4G networks• Key issues in Vehicle (V2X) communication• Wireless Body Area Networks, including specific Radio Channel Models for WBANs• Energy efficiency and resource management enhancements in Radio Access Networks• Definitions and models for the virtualised and cloud RAN architectures• Advances on feasible indoor localization and tracking techniques• Recent findings and innovations in antenna systems for communications• Physical Layer Network Coding for next generation wireless systems• Methods and techniques for MIMO Over the Air (OTA) testin

New Advances in Semiconductors

New Advances in Semiconductors brings together contributions from important researchers around the world on semiconductor materials and their applications. It includes seven chapters in two sections: “Calculations and Simulations in Semiconductors” and “Semiconductor Materials.” The world will emerge different after the social and economic reorganizations caused by the COVID-19 pandemic and will be even more dependent on semiconductors than ever before. New Advances in Semiconductors is a book that brings together the contributions of important researchers around the world and is able to give an idea about the different characteristics of semiconductor materials and their applications. There is a section dedicated to theory, calculations and logic and another dedicated to the development and characterization of semiconductor materials of great future interest. I really hope that this book will help to spread knowledge about this research field to other researchers and students working in this area or even to those interested in starting their more advanced studies

Compact Models for Integrated Circuit Design

This modern treatise on compact models for circuit computer-aided design (CAD) presents industry standard models for bipolar-junction transistors (BJTs), metal-oxide-semiconductor (MOS) field-effect-transistors (FETs), FinFETs, and tunnel field-effect transistors (TFETs), along with statistical MOS models. Featuring exercise problems at the end of each chapter and extensive references at the end of the book, the text supplies fundamental and practical knowledge necessary for efficient integrated circuit (IC) design using nanoscale devices. It ensures even those unfamiliar with semiconductor physics gain a solid grasp of compact modeling concepts