47,477 research outputs found
The OCarePlatform : a context-aware system to support independent living
Background: Currently, healthcare services, such as institutional care facilities, are burdened with an increasing number of elderly people and individuals with chronic illnesses and a decreasing number of competent caregivers. Objectives: To relieve the burden on healthcare services, independent living at home could be facilitated, by offering individuals and their (in)formal caregivers support in their daily care and needs. With the rise of pervasive healthcare, new information technology solutions can assist elderly people ("residents") and their caregivers to allow residents to live independently for as long as possible. Methods: To this end, the OCarePlatform system was designed. This semantic, data-driven and cloud based back-end system facilitates independent living by offering information and knowledge-based services to the resident and his/her (in)formal caregivers. Data and context information are gathered to realize context-aware and personalized services and to support residents in meeting their daily needs. This body of data, originating from heterogeneous data and information sources, is sent to personalized services, where is fused, thus creating an overview of the resident's current situation. Results: The architecture of the OCarePlatform is proposed, which is based on a service-oriented approach, together with its different components and their interactions. The implementation details are presented, together with a running example. A scalability and performance study of the OCarePlatform was performed. The results indicate that the OCarePlatform is able to support a realistic working environment and respond to a trigger in less than 5 seconds. The system is highly dependent on the allocated memory. Conclusion: The data-driven character of the OCarePlatform facilitates easy plug-in of new functionality, enabling the design of personalized, context-aware services. The OCarePlatform leads to better support for elderly people and individuals with chronic illnesses, who live independently. (C) 2016 Elsevier Ireland Ltd. All rights reserved
Machine Learning and Integrative Analysis of Biomedical Big Data.
Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues
ReCon: Revealing and Controlling PII Leaks in Mobile Network Traffic
It is well known that apps running on mobile devices extensively track and
leak users' personally identifiable information (PII); however, these users
have little visibility into PII leaked through the network traffic generated by
their devices, and have poor control over how, when and where that traffic is
sent and handled by third parties. In this paper, we present the design,
implementation, and evaluation of ReCon: a cross-platform system that reveals
PII leaks and gives users control over them without requiring any special
privileges or custom OSes. ReCon leverages machine learning to reveal potential
PII leaks by inspecting network traffic, and provides a visualization tool to
empower users with the ability to control these leaks via blocking or
substitution of PII. We evaluate ReCon's effectiveness with measurements from
controlled experiments using leaks from the 100 most popular iOS, Android, and
Windows Phone apps, and via an IRB-approved user study with 92 participants. We
show that ReCon is accurate, efficient, and identifies a wider range of PII
than previous approaches.Comment: Please use MobiSys version when referencing this work:
http://dl.acm.org/citation.cfm?id=2906392. 18 pages, recon.meddle.mob
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