Predicting Pancreatic Cancer Using Support Vector Machine

This report presents an approach to predict pancreatic cancer using Support Vector Machine Classification algorithm. The research objective of this project it to predict pancreatic cancer on just genomic, just clinical and combination of genomic and clinical data. We have used real genomic data having 22,763 samples and 154 features per sample. We have also created Synthetic Clinical data having 400 samples and 7 features per sample in order to predict accuracy of just clinical data. To validate the hypothesis, we have combined synthetic clinical data with subset of features from real genomic data. In our results, we observed that prediction accuracy, precision, recall with just genomic data is 80.77%, 20%, 4%. Prediction accuracy, precision, recall with just synthetic clinical data is 93.33%, 95%, 30%. While prediction accuracy, precision, recall for combination of real genomic and synthetic clinical data is 90.83%, 10%, 5%. The combination of real genomic and synthetic clinical data decreased the accuracy since the genomic data is weakly correlated. Thus we conclude that the combination of genomic and clinical data does not improve pancreatic cancer prediction accuracy. A dataset with more significant genomic features might help to predict pancreatic cancer more accurately

Sabanci-Okan system at ImageClef 2011: plant identication task

We describe our participation in the plant identication task of ImageClef 2011. Our approach employs a variety of texture, shape as well as color descriptors. Due to the morphometric properties of plants, mathematical morphology has been advocated as the main methodology for texture characterization, supported by a multitude of contour-based shape and color features. We submitted a single run, where the focus has been almost exclusively on scan and scan-like images, due primarily to lack of time. Moreover, special care has been taken to obtain a fully automatic system, operating only on image data. While our photo results are low, we consider our submission successful, since besides being our rst attempt, our accuracy is the highest when considering the average of the scan and scan-like results, upon which we had concentrated our eorts

Cancer diagnosis using deep learning: A bibliographic review

In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann’s machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements

Predictive Maintenance on the Machining Process and Machine Tool

This paper presents the process required to implement a data driven Predictive Maintenance (PdM) not only in the machine decision making, but also in data acquisition and processing. A short review of the different approaches and techniques in maintenance is given. The main contribution of this paper is a solution for the predictive maintenance problem in a real machining process. Several steps are needed to reach the solution, which are carefully explained. The obtained results show that the Preventive Maintenance (PM), which was carried out in a real machining process, could be changed into a PdM approach. A decision making application was developed to provide a visual analysis of the Remaining Useful Life (RUL) of the machining tool. This work is a proof of concept of the methodology presented in one process, but replicable for most of the process for serial productions of pieces

Personalized Pancreatic Tumor Growth Prediction via Group Learning

Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models yield promising results, their prediction accuracy may be limited by the absence of population trend data and personalized clinical characteristics. In this paper, we propose a statistical group learning approach to predict the tumor growth pattern that incorporates both the population trend and personalized data, in order to discover high-level features from multimodal imaging data. A deep convolutional neural network approach is developed to model the voxel-wise spatio-temporal tumor progression. The deep features are combined with the time intervals and the clinical factors to feed a process of feature selection. Our predictive model is pretrained on a group data set and personalized on the target patient data to estimate the future spatio-temporal progression of the patient's tumor. Multimodal imaging data at multiple time points are used in the learning, personalization and inference stages. Our method achieves a Dice coefficient of 86.8% +- 3.6% and RVD of 7.9% +- 5.4% on a pancreatic tumor data set, outperforming the DSC of 84.4% +- 4.0% and RVD 13.9% +- 9.8% obtained by a previous state-of-the-art model-based method

Offline signature verification using classifier combination of HOG and LBP features

We present an offline signature verification system based on a signature’s local histogram features. The signature is divided into zones using both the Cartesian and polar coordinate systems and two different histogram features are calculated for each zone: histogram of oriented gradients (HOG) and histogram of local binary patterns (LBP). The classification is performed using Support Vector Machines (SVMs), where two different approaches for training are investigated, namely global and user-dependent SVMs. User-dependent SVMs, trained separately for each user, learn to differentiate a user’s signature from others, whereas a single global SVM trained with difference vectors of query and reference signatures’ features of all users, learns how to weight dissimilarities. The global SVM classifier is trained using genuine and forgery signatures of subjects that are excluded from the test set, while userdependent SVMs are separately trained for each subject using genuine and random forgeries. The fusion of all classifiers (global and user-dependent classifiers trained with each feature type), achieves a 15.41% equal error rate in skilled forgery test, in the GPDS-160 signature database without using any skilled forgeries in training