The pseudotemporal bootstrap for predicting glaucoma from cross-sectional visual field data

Progressive loss of the field of vision is characteristic of a number of eye diseases such as glaucoma, a leading cause of irreversible blindness in the world. Recently, there has been an explosion in the amount of data being stored on patients who suffer from visual deterioration, including visual field (VF) test, retinal image, and frequent intraocular pressure measurements. Like the progression of many biological and medical processes, VF progression is inherently temporal in nature. However, many datasets associated with the study of such processes are often cross sectional and the time dimension is not measured due to the expensive nature of such studies. In this paper, we address this issue by developing a method to build artificial time series, which we call pseudo time series from cross-sectional data. This involves building trajectories through all of the data that can then, in turn, be used to build temporal models for forecasting (which would otherwise be impossible without longitudinal data). Glaucoma, like many diseases, is a family of conditions and it is, therefore, likely that there will be a number of key trajectories that are important in understanding the disease. In order to deal with such situations, we extend the idea of pseudo time series by using resampling techniques to build multiple sequences prior to model building. This approach naturally handles outliers and multiple possible disease trajectories. We demonstrate some key properties of our approach on synthetic data and present very promising results on VF data for predicting glaucoma

VIQID: a no-reference bit stream-based visual quality impairment detector

In order to ensure adequate quality towards the end users at all time, video service providers are getting more interested in monitoring their video streams. Objective video quality metrics provide a means of measuring (audio)visual quality in an automated manner. Unfortunately, most of the current existing metrics cannot be used for real-time monitoring due to their dependencies on the original video sequence. In this paper we present a new objective video quality metric which classifies packet loss as visible or invisible based on information extracted solely from the captured encoded H.264/AVC video bit stream. Our results show that the visibility of packet loss can be predicted with a high accuracy, without the need for deep packet inspection. This enables service providers to monitor quality in real-time