42,554 research outputs found
Storage Solutions for Big Data Systems: A Qualitative Study and Comparison
Big data systems development is full of challenges in view of the variety of
application areas and domains that this technology promises to serve.
Typically, fundamental design decisions involved in big data systems design
include choosing appropriate storage and computing infrastructures. In this age
of heterogeneous systems that integrate different technologies for optimized
solution to a specific real world problem, big data system are not an exception
to any such rule. As far as the storage aspect of any big data system is
concerned, the primary facet in this regard is a storage infrastructure and
NoSQL seems to be the right technology that fulfills its requirements. However,
every big data application has variable data characteristics and thus, the
corresponding data fits into a different data model. This paper presents
feature and use case analysis and comparison of the four main data models
namely document oriented, key value, graph and wide column. Moreover, a feature
analysis of 80 NoSQL solutions has been provided, elaborating on the criteria
and points that a developer must consider while making a possible choice.
Typically, big data storage needs to communicate with the execution engine and
other processing and visualization technologies to create a comprehensive
solution. This brings forth second facet of big data storage, big data file
formats, into picture. The second half of the research paper compares the
advantages, shortcomings and possible use cases of available big data file
formats for Hadoop, which is the foundation for most big data computing
technologies. Decentralized storage and blockchain are seen as the next
generation of big data storage and its challenges and future prospects have
also been discussed
A Taxonomy of Data Grids for Distributed Data Sharing, Management and Processing
Data Grids have been adopted as the platform for scientific communities that
need to share, access, transport, process and manage large data collections
distributed worldwide. They combine high-end computing technologies with
high-performance networking and wide-area storage management techniques. In
this paper, we discuss the key concepts behind Data Grids and compare them with
other data sharing and distribution paradigms such as content delivery
networks, peer-to-peer networks and distributed databases. We then provide
comprehensive taxonomies that cover various aspects of architecture, data
transportation, data replication and resource allocation and scheduling.
Finally, we map the proposed taxonomy to various Data Grid systems not only to
validate the taxonomy but also to identify areas for future exploration.
Through this taxonomy, we aim to categorise existing systems to better
understand their goals and their methodology. This would help evaluate their
applicability for solving similar problems. This taxonomy also provides a "gap
analysis" of this area through which researchers can potentially identify new
issues for investigation. Finally, we hope that the proposed taxonomy and
mapping also helps to provide an easy way for new practitioners to understand
this complex area of research.Comment: 46 pages, 16 figures, Technical Repor
Secure and Trustable Electronic Medical Records Sharing using Blockchain
Electronic medical records (EMRs) are critical, highly sensitive private
information in healthcare, and need to be frequently shared among peers.
Blockchain provides a shared, immutable and transparent history of all the
transactions to build applications with trust, accountability and transparency.
This provides a unique opportunity to develop a secure and trustable EMR data
management and sharing system using blockchain. In this paper, we present our
perspectives on blockchain based healthcare data management, in particular, for
EMR data sharing between healthcare providers and for research studies. We
propose a framework on managing and sharing EMR data for cancer patient care.
In collaboration with Stony Brook University Hospital, we implemented our
framework in a prototype that ensures privacy, security, availability, and
fine-grained access control over EMR data. The proposed work can significantly
reduce the turnaround time for EMR sharing, improve decision making for medical
care, and reduce the overall costComment: AMIA 2017 Annual Symposium Proceeding
A Technology Proposal for a Management Information System for the Director’s Office, NAL.
This technology proposal attempts in giving a viable solution for a Management Information System (MIS) for the Director's Office. In today's IT scenario, an Organization's success greatly depends on its ability to get accurate and timely data on its operations of varied nature and to manage this data effectively to guide its activities and meet its goals. To cater to the information needs of an Organization or an Office like the Director's Office, information systems are developed and deployed to gather and process data in ways that produce a variety of information to the end-user. MIS can therefore can be defined as an integrated user-machine system for providing information to support operations, management and decision-making functions in an Organization. The system in a nutshell, utilizes computer hardware and software, manual procedures, models for analysis planning, control and decision-making and a database. Using state-of-the-art front-end and back-end web based tools, this technology proposal attempts to provide a single-point Information Management, Information Storage, Information Querying and Information Retrieval interface to the Director and his office for handling all information traffic flow in and out of the Director's Office
Assessment of the genetic basis of rosacea by genome-wide association study.
Rosacea is a common, chronic skin disease that is currently incurable. Although environmental factors influence rosacea, the genetic basis of rosacea is not established. In this genome-wide association study, a discovery group of 22,952 individuals (2,618 rosacea cases and 20,334 controls) was analyzed, leading to identification of two significant single-nucleotide polymorphisms (SNPs) associated with rosacea, one of which replicated in a new group of 29,481 individuals (3,205 rosacea cases and 26,262 controls). The confirmed SNP, rs763035 (P=8.0 × 10(-11) discovery group; P=0.00031 replication group), is intergenic between HLA-DRA and BTNL2. Exploratory immunohistochemical analysis of HLA-DRA and BTNL2 expression in papulopustular rosacea lesions from six individuals, including one with the rs763035 variant, revealed staining in the perifollicular inflammatory infiltrate of rosacea for both proteins. In addition, three HLA alleles, all MHC class II proteins, were significantly associated with rosacea in the discovery group and confirmed in the replication group: HLA-DRB1*03:01 (P=1.0 × 10(-8) discovery group; P=4.4 × 10(-6) replication group), HLA-DQB1*02:01 (P=1.3 × 10(-8) discovery group; P=7.2 × 10(-6) replication group), and HLA-DQA1*05:01 (P=1.4 × 10(-8) discovery group; P=7.6 × 10(-6) replication group). Collectively, the gene variants identified in this study support the concept of a genetic component for rosacea, and provide candidate targets for future studies to better understand and treat rosacea
On-Demand Big Data Integration: A Hybrid ETL Approach for Reproducible Scientific Research
Scientific research requires access, analysis, and sharing of data that is
distributed across various heterogeneous data sources at the scale of the
Internet. An eager ETL process constructs an integrated data repository as its
first step, integrating and loading data in its entirety from the data sources.
The bootstrapping of this process is not efficient for scientific research that
requires access to data from very large and typically numerous distributed data
sources. a lazy ETL process loads only the metadata, but still eagerly. Lazy
ETL is faster in bootstrapping. However, queries on the integrated data
repository of eager ETL perform faster, due to the availability of the entire
data beforehand.
In this paper, we propose a novel ETL approach for scientific data
integration, as a hybrid of eager and lazy ETL approaches, and applied both to
data as well as metadata. This way, Hybrid ETL supports incremental integration
and loading of metadata and data from the data sources. We incorporate a
human-in-the-loop approach, to enhance the hybrid ETL, with selective data
integration driven by the user queries and sharing of integrated data between
users. We implement our hybrid ETL approach in a prototype platform, Obidos,
and evaluate it in the context of data sharing for medical research. Obidos
outperforms both the eager ETL and lazy ETL approaches, for scientific research
data integration and sharing, through its selective loading of data and
metadata, while storing the integrated data in a scalable integrated data
repository.Comment: Pre-print Submitted to the DMAH Special Issue of the Springer DAPD
Journa
A soa-based e-government data integration
Data Integration presents a core issue in the Palestinian e-Government Technical Framework. The currently used data integration model relies on the Integrated Central Database which lacks quality attributes such as: interoperability and flexibility. We purpose a SOA-based approach for data integration that achieves the above attributes. We present and analyze the current architecture and implementation of the Palestinian e-Government Integrated Central Database model. We transform the current model into a SOA framework that is realized using Enterprise Service Bus (ESB) and Web Services. The proposed framework offers database replication and connectivity functionalities for the Central Database. The proposed framework is evaluated using a scenario-based software architecture evaluation method and proves that it achieves the framework goals of quality attributes: interoperability and flexibility. Moreover, a prototype of the framework is implemented and validates the framework correctness. A specific usage is presented and further proves that the framework accomplishes its functionality and quality attributes
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