Establishment and operation of a Good Manufacturing Practice-compliant allogeneic Epstein-Barr virus (EBV)-specific cytotoxic cell bank for the treatment of EBV-associated lymphoproliferative disease

Funded by Wellcome Trust Translational Award SNBTSPeer reviewedPublisher PD

Spartan Daily, February 25, 1981

Volume 76, Issue 21https://scholarworks.sjsu.edu/spartandaily/6725/thumbnail.jp

Haematological malignancy: are we measuring what is important to patients? A systematic review of quality of life instruments

© 2018 The Authors. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.The wide range of health‐related quality‐of‐life (HRQoL) instruments used in haematology makes it challenging for haematologists and other care team members in practice to select, use and understand the scoring system and finally interpret the results. The main objectives of this study were to: (a) provide a comprehensive list of quality‐of‐life issues important to patients suffering from haematological malignancies, identified through the literature; (b) provide a list of health‐related quality‐of‐life (HRQoL) instruments used in haematological malignancies in both daily clinical practice and research; and (c) evaluate the relevance and comprehensibility of the identified instruments in haematological malignancies. Systematic literature review of two databases, followed by addition of articles by manual searching, was carried out. The articles focusing on the primary studies, which have used semi‐structured/structured interviews or surveys to identify issues important to HM patients, and other studies describing the results of testing measurement properties, such as reliability, validity and responsiveness of the instruments currently used to evaluate the HRQoL in different HMs, were included. Fifty‐seven studies reported development and validation of 30 HRQoL instruments, which have been used in haematology. Twenty‐four studies were identified using qualitative methods to report HRQoL issues and symptoms from a patient's perspective. No identified instrument captured all the issues identified from the qualitative studies. None of the instruments reviewed appeared to have been developed for use in clinical practice and specifically for patients with HM, except MyPOS. Furthermore, measurement properties were established, largely, in clinical trial scenarios. There is a need for development of a new HRQoL instrument entirely based on involvement of patients with haematological malignancies.Peer reviewe

Access Magazine, May 2015

https://scholarworks.sjsu.edu/accessmagazine/1013/thumbnail.jp

Biology, Ecology, and Management of Deer in the Chicago Metropolitan Area W-87-R-8, Annual Job Progress Report

Annual Job Progress Report July 1, 1986 - June 30, 1987 issued September 28, 1987. Includes Appendix A: Helminthic and protozoan parasites of white-tailed deer in urban areas of northeastern Illinois, Jose G. Cisneros; Appendix B: Recommendations for a cooperative new initiative on urban deer management for Cook County, Illinois; Appendix C: Recommendations for deer removal on O'Hare International Airport.Report issued on: 28 September 1987INHS Technical Report prepared for Illinois Department of Conservation Division of Wildlife Resource

Parks, Buffer Zones, and Costly Enforcement

The reality of protected area management is that enforcing forest and park boundaries is costly and so most likely incomplete, due in part to the pressures exerted on the boundaries by local people who often have traditionally relied on the park resources. Buffer zones are increasingly being proposed and implemented to protect both forest resources and livelihoods. Developing a spatially-explicit optimal enforcement model, this paper demonstrates that there is a trade-off between the amount spent on enforcement, the size of a formal buffer zone, and the extent to which a forest can be protected from illegal extraction. Indeed, given the reality of limited enforcement budgets, a forest manager with a mandate to protect a whole forest may in fact end up doing a worse job than one who is able to incorporate an appropriately sized buffer zone into their management plans that, combined with more effective enforcement of a smaller exclusion zone, provide the appropriate incentives for villagers to extract only in the periphery of the forest, rather than venture further into the forest.

The Continuous Challenge of Diagnosing patients with Fabry disease in Argentina : Genotype, Experiences, Anecdotes, and New Learnings

The lysosomal storage disorder Fabry disease (FD) is caused by pathogenic mutations in the α-galactosidase A gene, localized in X chromosome. Deficient enzymatic activity of the product of this gene, the lysosomal hydrolase α-galactosidase A, leads to accumulation of its substrate globotriaosylceramide. Diagnosis of FD starts with clinical suspicion followed by confirmatory laboratory testing. The aim of this work is to report the 14 years’ experience and learnings in the diagnosis of patients with Fabry disease in Argentina from a specialized lysosomal diseases diagnosis laboratory and to report the genotype characterization of the 25 families from Argentina with FD detected by us.Fil: Rozenfeld, Paula Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Ceci, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Roa, Norma. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Kisinovsky, Isaac. Sanatorio Urquiza; Argentin

The Effect of Business Improvement Methods on Innovation in Small and Medium-Sized Enterprises in Peripheral Regions

The effect of business improvement methods on innovation in small and medium-sized enterprises in peripheral regions, Regional Studies. This paper tests whether commonly used business improvement methods (BIM) foster or inhibit innovation in small and medium-sized enterprises (SMEs) in peripheral regions. The findings show that adopting BIM diverts firms away from successful innovation (i.e., in terms of new products/services and new processes in the past three years), and instead is associated with undertaking innovation-related activities while remaining non-innovators. Indeed, reinforcing BIM (through greater ‘depth’ of use) may lead to further exclusion from successful innovation