20,919 research outputs found
The Infrared Imaging Spectrograph (IRIS) for TMT: optical design of IRIS imager with "Co-axis double TMA"
IRIS (InfraRed Imaging Spectrograph) is one of the first-generation
instruments for the Thirty Meter Telescope (TMT). IRIS is composed of a
combination of near-infrared (0.84--2.4 m) diffraction limited imager and
integral field spectrograph. To achieve near-diffraction limited resolutions in
the near-infrared wavelength region, IRIS uses the advanced adaptive optics
system NFIRAOS (Narrow Field Infrared Adaptive Optics System) and integrated
on-instrument wavefront sensors (OIWFS). However, IRIS itself has challenging
specifications. First, the overall system wavefront error should be less than
40 nm in Y, z, J, and H-band and 42 nm in K-band over a 34.0 34.0
arcsecond field of view. Second, the throughput of the imager components should
be more than 42 percent. To achieve the extremely low wavefront error and high
throughput, all reflective design has been newly proposed. We have adopted a
new design policy called "Co-Axis double-TMA", which cancels the asymmetric
aberrations generated by "collimator/TMA" and "camera/TMA" efficiently. The
latest imager design meets all specifications, and, in particular, the
wavefront error is less than 17.3 nm and throughput is more than 50.8 percent.
However, to meet the specification of wavefront error and throughput as built
performance, the IRIS imager requires both mirrors with low surface
irregularity after high-reflection coating in cryogenic and high-level Assembly
Integration and Verification (AIV). To deal with these technical challenges, we
have done the tolerance analysis and found that total pass rate is almost 99
percent in the case of gauss distribution and more than 90 percent in the case
of parabolic distribution using four compensators. We also have made an AIV
plan and feasibility check of the optical elements. In this paper, we will
present the details of this optical system.Comment: 18 pages, 14 figures, Proceeding 9908-386 of the SPIE Astronomical
Telescopes + Instrumentation 201
Statistical methods for tissue array images - algorithmic scoring and co-training
Recent advances in tissue microarray technology have allowed
immunohistochemistry to become a powerful medium-to-high throughput analysis
tool, particularly for the validation of diagnostic and prognostic biomarkers.
However, as study size grows, the manual evaluation of these assays becomes a
prohibitive limitation; it vastly reduces throughput and greatly increases
variability and expense. We propose an algorithm - Tissue Array Co-Occurrence
Matrix Analysis (TACOMA) - for quantifying cellular phenotypes based on
textural regularity summarized by local inter-pixel relationships. The
algorithm can be easily trained for any staining pattern, is absent of
sensitive tuning parameters and has the ability to report salient pixels in an
image that contribute to its score. Pathologists' input via informative
training patches is an important aspect of the algorithm that allows the
training for any specific marker or cell type. With co-training, the error rate
of TACOMA can be reduced substantially for a very small training sample (e.g.,
with size 30). We give theoretical insights into the success of co-training via
thinning of the feature set in a high-dimensional setting when there is
"sufficient" redundancy among the features. TACOMA is flexible, transparent and
provides a scoring process that can be evaluated with clarity and confidence.
In a study based on an estrogen receptor (ER) marker, we show that TACOMA is
comparable to, or outperforms, pathologists' performance in terms of accuracy
and repeatability.Comment: Published in at http://dx.doi.org/10.1214/12-AOAS543 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Plasma Processing of III-V Materials for Energy Efficient Electronics Applications
This paper reviews some recent activity at the James Watt Nanofabrication Centre in the University of Glasgow in the area of plasma processing for energy efficient compound semiconductor-based transistors. Atomic layer etching suitable for controllable recess etching in GaN power transistors will be discussed. In addition, plasma based surface passivation techniques will be reviewed for a variety of compound semiconductor materials ((100) and (110) oriented InGaAs and InGaSb)
Modelling the behaviour of microbulk Micromegas in Xenon/trimethylamine gas
We model the response of a state of the art micro-hole single-stage charge
amplication device (`microbulk' Micromegas) in a gaseous atmosphere consisting
of Xenon/trimethylamine at various concentrations and pressures. The amplifying
structure, made with photo-lithographic techniques similar to those followed in
the fabrication of gas electron multipliers (GEMs), consisted of a 100 um-side
equilateral-triangle pattern with 50 um-diameter holes placed at its vertexes.
Once the primary electrons are guided into the holes by virtue of an optimized
field configuration, avalanches develop along the 50 um-height channels etched
out of the original doubly copper-clad polyimide foil. In order to properly
account for the strong field gradients at the holes' entrance as well as for
the fluctuations of the avalanche process (that ultimately determine the
achievable energy resolution), we abandoned the hydrodynamic framework,
resorting to a purely microscopic description of the electron trajectories as
obtained from elementary cross-sections. We show that achieving a satisfactory
description needs additional assumptions about atom-molecule (Penning) transfer
reactions and charge recombination to be made
An Efficient Data-aided Synchronization in L-DACS1 for Aeronautical Communications
L-band Digital Aeronautical Communication System type-1 (L-DACS1) is an
emerging standard that aims at enhancing air traffic management (ATM) by
transitioning the traditional analog aeronautical communication systems to the
superior and highly efficient digital domain. L-DACS1 employs modern and
efficient orthogonal frequency division multiplexing (OFDM) modulation
technique to achieve more efficient and higher data rate in comparison to the
existing aeronautical communication systems. However, the performance of OFDM
systems is very sensitive to synchronization errors. L-DACS1 transmission is in
the L-band aeronautical channels that suffer from large interference and large
Doppler shifts, which makes the synchronization for L-DACS more challenging.
This paper proposes a novel computationally efficient synchronization method
for L-DACS1 systems that offers robust performance. Through simulation, the
proposed method is shown to provide accurate symbol timing offset (STO)
estimation as well as fractional carrier frequency offset (CFO) estimation in a
range of aeronautical channels. In particular, it can yield excellent
synchronization performance in the face of a large carrier frequency offset.Comment: In the proceeding of International Conference on Data Mining,
Communications and Information Technology (DMCIT
Recommended from our members
Trace doping of multiple elements enables stable battery cycling of LiCoO2 at 4.6 V
LiCoO2 is a dominant cathode material for lithium-ion (Li-ion) batteries due to its high volumetric energy density, which could potentially be further improved by charging to high voltages. However, practical adoption of high-voltage charging is hindered by LiCoO2’s structural instability at the deeply delithiated state and the associated safety concerns. Here, we achieve stable cycling of LiCoO2 at 4.6 V (versus Li/Li+) through trace Ti–Mg–Al co-doping. Using state-of-the-art synchrotron X-ray imaging and spectroscopic techniques, we report the incorporation of Mg and Al into the LiCoO2 lattice, which inhibits the undesired phase transition at voltages above 4.5 V. We also show that, even in trace amounts, Ti segregates significantly at grain boundaries and on the surface, modifying the microstructure of the particles while stabilizing the surface oxygen at high voltages. These dopants contribute through different mechanisms and synergistically promote the cycle stability of LiCoO2 at 4.6 V
- …