75 research outputs found
Book of Abstracts 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and 3rd Conference on Imaging and Visualization
In this edition, the two events will run together as a single conference, highlighting the strong connection with the Taylor & Francis journals: Computer Methods in Biomechanics and Biomedical Engineering (John Middleton and Christopher Jacobs, Eds.) and Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization (JoãoManuel R.S. Tavares, Ed.).
The conference has become a major international meeting on computational biomechanics, imaging andvisualization. In this edition, the main program includes 212 presentations. In addition, sixteen renowned researchers will give plenary keynotes, addressing current challenges in computational biomechanics and biomedical imaging.
In Lisbon, for the first time, a session dedicated to award the winner of the Best Paper in CMBBE Journal will take place.
We believe that CMBBE2018 will have a strong impact on the development of computational biomechanics and biomedical imaging and visualization, identifying emerging areas of research and promoting the collaboration and networking between participants. This impact is evidenced through the well-known research groups, commercial companies and scientific organizations, who continue to support and sponsor the CMBBE meeting
series. In fact, the conference is enriched with five workshops on specific scientific topics and commercial software.info:eu-repo/semantics/draf
Model-based segmentation and registration of multimodal medical images
Ph.DDOCTOR OF PHILOSOPH
Novel methodology for assessing cement injection behaviour in cancellous bone
Understanding the cement injection behaviour in cancellous bone and accurately predicting the cement placement within the vertebral body is extremely challenging. We propose a novel method using reproducible and pathologically representative 2D and 3D bone surrogates to help study the influence of cement properties on injection behaviour.
Bespoke methodology was developed to control the injection volume and flow rate, measure the injection pressure, and allow visualization and quantitative analysis of the
spreading distribution. Morphology analysis showed that the variability in the 2D and 3D bone surrogates was very low, indicating that the geometrical structure of the surrogates
was constant. The overall pore size of the surrogates was very similar to that reported for human osteoporotic vertebral cancellous bone, indicating that the surrogates were pathologically representative. Injections performed into the 3D surrogates revealed that an increase in the fluid starting viscosity significantly increases the injection pressure in all surrogates, decreases the risk of leakage for osteoporosis surrogates only, decreases the
mean spreading distance for multiple myeloma surrogates only and increases the sphericity causing a more uniform spreading pattern for the metastasis surrogates only.
Injections performed into the 2D surrogates highlighted the influence of cement formulations and model structure on the injection behaviour and showed that (i) cements with similar composition/particle size have similar flow behaviour, (ii) cements with a high liquid-to-powder ratio cause irregular filling patterns and have a high risk of leakage, and (iii) the injection behaviour of certain cement formulations improves in the presence
of lesion or fracture, suggesting the notion of pathology specific bone cements. The developed methodology provides a fast, robust tool for discerning subtle differences in
bone cement formulations and allows comprehensive assessment of cement flow behaviour through controlling the surrogate morphology, controlling the injection
parameters, measuring the injection pressure, and allowing the visualization and quantitative analysis of the spreading distribution. The advantage of this methodology is
that it provides a clinically relevant representation of cement flow patterns and a tool for validating computational simulations
Fine‐structure processing, frequency selectivity and speech perception in hearing‐impaired listeners
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