Learning sound representations using trainable COPE feature extractors

Sound analysis research has mainly been focused on speech and music processing. The deployed methodologies are not suitable for analysis of sounds with varying background noise, in many cases with very low signal-to-noise ratio (SNR). In this paper, we present a method for the detection of patterns of interest in audio signals. We propose novel trainable feature extractors, which we call COPE (Combination of Peaks of Energy). The structure of a COPE feature extractor is determined using a single prototype sound pattern in an automatic configuration process, which is a type of representation learning. We construct a set of COPE feature extractors, configured on a number of training patterns. Then we take their responses to build feature vectors that we use in combination with a classifier to detect and classify patterns of interest in audio signals. We carried out experiments on four public data sets: MIVIA audio events, MIVIA road events, ESC-10 and TU Dortmund data sets. The results that we achieved (recognition rate equal to 91.71% on the MIVIA audio events, 94% on the MIVIA road events, 81.25% on the ESC-10 and 94.27% on the TU Dortmund) demonstrate the effectiveness of the proposed method and are higher than the ones obtained by other existing approaches. The COPE feature extractors have high robustness to variations of SNR. Real-time performance is achieved even when the value of a large number of features is computed.Comment: Accepted for publication in Pattern Recognitio

Automated detection of breast cancer using SAXS data and wavelet features

The overarching goal of this project was to improve breast cancer screening protocols first by collecting small angle x-ray scattering (SAXS) images from breast biopsy tissue, and second, by applying pattern recognition techniques as a semi-automatic screen. Wavelet based features were generated from the SAXS image data. The features were supplied to a classifier, which sorted the images into distinct groups, such as “normal” and “tumor”. The main problem in the project was to find a set of features that provided sufficient separation for classification into groups of “normal” and “tumor.” In the original SAXS patterns, information useful for classification was obscured. The wavelet maps allowed new scale-based information to be uncovered from each SAXS pattern. The new information was subsequently used to define features that allowed for classification. Several calculations were tested to extract useful features from the wavelet decomposition maps. The wavelet map average intensity feature was selected as the most promising feature. The wavelet map intensity feature was improved by using pre-processing to remove the high central intensities from the SAXS patterns, and by using different wavelet bases for the wavelet decomposition. The investigation undertaken for this project showed very promising results. A classification rate of 100% was achieved for distinguishing between normal samples and tumor samples. The system also showed promising results when tested on unrelated MRI data. In the future, the semi-automatic pattern recognition tool developed for this project could be automated. With a larger set of data for training and testing, the tool could be improved upon and used to assist radiologists in the detection and classification of breast lesions

Quantitative ultrasound texture analysis of fetal lungs to predict neonatal respiratory morbidity

Objective To develop and evaluate the performance of a novel method for predicting neonatal respiratory morbidity based on quantitative analysis of the fetal lung by ultrasound. Methods More than 13¿000 non-clinical images and 900 fetal lung images were used to develop a computerized method based on texture analysis and machine learning algorithms, trained to predict neonatal respiratory morbidity risk on fetal lung ultrasound images. The method, termed ‘quantitative ultrasound fetal lung maturity analysis’ (quantusFLM™), was then validated blindly in 144 neonates, delivered at 28¿+¿0 to 39¿+¿0¿weeks' gestation. Lung ultrasound images in DICOM format were obtained within 48¿h of delivery and the ability of the software to predict neonatal respiratory morbidity, defined as either respiratory distress syndrome or transient tachypnea of the newborn, was determined. Results Mean (SD) gestational age at delivery was 36¿+¿1 (3¿+¿3) weeks. Among the 144 neonates, there were 29 (20.1%) cases of neonatal respiratory morbidity. Quantitative texture analysis predicted neonatal respiratory morbidity with a sensitivity, specificity, positive predictive value and negative predictive value of 86.2%, 87.0%, 62.5% and 96.2%, respectively. Conclusions Quantitative ultrasound fetal lung maturity analysis predicted neonatal respiratory morbidity with an accuracy comparable to that of current tests using amniotic fluid.Peer ReviewedPostprint (published version