34 research outputs found

    Immunization and Autism of Children 3 to 16 Years Old in Rumah Autis Bekasi

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    Autism is defined as neurology disorder affecting brain functionalities so that resulting communication, social interaction, behavior difficulties and the symptom appears before age 3. This study is aimed at understanding the factors related to autism cases in Rumah Autis Bekasi. Methods: There variables in this study namely, independent variable was immunization and dependent variable was autism and confounding variable were genetic, parents’ age, maternal health history during pregnancy, and medication during pregnancy. Primary data collected through questionaire and interview to the families of autism. This is a case study on 60 samples divided into 30 samples of autism in Rumah Autis and 30 samples of normal people living nearby with the proportion 1:1. The data were analyzed using univariate, bivariate using chi square test, and multivariate statistical analysis using regresi logistic. The results show that there is no correlation between immunization history and the autism with p-value 0.774>0.05. There is a correlation between the father’s age and the autism with p-value 0.038<0.05 and OR 0.333,there is a significant relationship between maternal health history and autism with p-value 0.038<0.05 and OR 3.763 and multivariate analysis shows that the most dominant variable is maternal health history with p-value 0.019 and OR 13.496. This study suggests that the pregnant women should check up their condition if there are some health problems and taking medication without doctor’s prescription. Keyword: Immunization, Autism, Children 3 to 16 years ol

    Visual symptoms in Parkinson's disease and Parkinson's disease dementia

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    Non-motor symptoms such as dementia and visual hallucinations are key determinants of long-term outcome and quality of life in Parkinson’s disease (PD). Attempting to understand these issues better was the motivation behind this thesis. A major aim of the study was to characterise the visual symptoms experienced by patients with PD and PD dementia, focussing not just on complex visual hallucinations, whose prognostic implications are already well-described, but also on a range of other visual symptoms including illusory misperceptions, sensations of passage and presence and double vision. A major objective was to define key measures of visual exploration strategy during visuocognitive assessment and examine the link between strategy, cognition and visual and motor symptoms. We also set out to examine the utility of retina-specific visual assessment techniques to define the potential role of retinal dysfunction in visual impairment and symptomatology. A major finding of this study was that not all visual symptoms share a common pathophysiological basis. Our results argue in favour of splitting hallucinations into separate phenomenological groups in order to better define causation and predictive value in future longitudinal studies. In addition, exploration strategy on a variety of visual tasks was demonstrated to be significantly less efficient in subjects with perceptual difficulties, providing insight into the interaction between cognition and eye movements in PD. Retinal structure, as assessed by optical coherence tomography, was not significantly altered in PD and our results would caution against the use of this technique as a disease biomarker until more is known about the limitations of this method. Finally, our neurophysiological assessment hints at the retina as the site of diminished visual acuity in PD despite there being no striking differences in central and peripheral retinal responses between control and PD subjects.EThOS - Electronic Theses Online ServiceParkinson's UK : UK NIHR Biomedical Research Centre for Ageing and Age-Related Disease : Newcastle upon Tyne Hospitals NHS Foundation TrustGBUnited Kingdo

    Relationship of Attitude about Premarital Pregnancy and the Incidence of Premarital Pregnancies in Kulon Progo 2015

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    Based on Kulon Progo Health Department report in 2012, there were 25% of brides were positively pregnant. In 2013, around 44% of brides were already pregnant. Pre-marital preganancy is influenced by internal and external factors, one of them is attitude about pre-marital pregnancy. This research aims to determine the relationship between attitude about pre-marital pregnancy and pre-marital pregnancy incidence in Kulon Progo. This research is observational research with cross sectional design. The population is brides in Kulon Progo in 2015. The sampel was obtained by simple random sampling, 120 respondents from 1 Community Health Center in every district with inclusive criteria of graduate from elementary school and exclusive criteria of health workers. The independent variable was attitude about pre-marital pregnancy. The dependent variable was pre-marital pregnancy. The instruments were questionairre and data collecting format. The data were analyzed using correlation analysis chi-square with significant level of 5% (p=0,05). This study showed that most of the brides in Kulon Progo were in the age of 20-30 years old, midly educated, and employed. Pre-marital marriage in brides in Kulon Progo was 15 people (12,5). Most of the brides in Kulon Progo had positive attitude about premarital marriage. The Conclusion is there is a significant relationship between attitude about pre-marital marriage and pre-marital pregnancy incidence. Keywords: pre-marital pregnancy, incidence of pre-marital pregnanc

    PROCEEDING BOOK THE 3rd INTERNATIONAL CONFERENCE ON HEALTH SCIENCE 2016 “Optimizing the Mental Health under SDGs”

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    PROCEEDING BOOK THE 3rd INTERNATIONAL CONFERENCE ON HEALTH SCIENCE 2016 “Optimizing theMental Health under SDGs”

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    Dear honorary guests and participants, It is our great pleasure to invite you in The International Conference on Health Science Named “Optimizing the Mental Health under Sustainable Development Goals (SDGs)”. This event is held annually to improve the quality of Yogyakarta Health Polytechnic as a referral institution. The third aim from SDGs’s seventeen aim is to ensure our life healthy and to improve welfare to all people in all ages. That aim has 13 targets of national health system, one of them is in 2030 can decrease one over three of premature death because of Non-communicable diseases and cares, and to improve health also mental health. Mental health is important same as physics health and we have to keep them. Mental health from one person is different from the other, they can change because environmental changes and we have to pass life phase. We hope that we can keep it to have a good mental health, and we hope this conference can give contribution to develop the role of institution supporting Sustainable Development Goals (SDGs). In this meeting we present great qualification scientists to share knowledge and experiences in health sciences such as midwifery, nursing, dental health, environmental health, health analyst, nutrition, and health of community. Health practitioners, students and lecturer are also welcome to the conference. They can share and improve their knowledge in harmonic science atmosphere to get another view of health science. We hope this conference can be one of tools to communicate and interact between those who related to health science. We hope you all enjoy this conference and we would like welcome you in Yogyakarta

    Aerospace Medicine and Biology: A cumulative index to the 1982 issues

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    This publication is a cumulative index to the abstracts contained in the Supplements 229 through 240 of Aerospace Medicine and Biology: A continuing Bibliography. It includes three indexes: subject, personal author, and corporate source

    Misfolded proteins affect synaptic plasticity and network activity

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    Life Sciences Program Tasks and Bibliography for FY 1996

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    This document includes information on all peer reviewed projects funded by the Office of Life and Microgravity Sciences and Applications, Life Sciences Division during fiscal year 1996. This document will be published annually and made available to scientists in the space life sciences field both as a hard copy and as an interactive Internet web page

    Deprescribing tool for STOPPFall (screening tool of older persons prescriptions in older adults with high fall risk) items

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    Background: Health care professionals are often reluctant to deprescribe fall-risk-increasing drugs (FRIDs). Lack of knowledge and skills form a significant barrier. To support clinicians in the management of FRIDs and to facilitate the deprescribing process, a deprescribing tool was developed by a European expert group for STOPPFall (Screening Tool of Older Persons Prescriptions in older adults with high fall risk) items. Methods: STOPPFall was created using an expert Delphi consensus process in 2019 and in 2020, 24 panellists from EuGMS SIG on Pharmacology and Task and Finish on FRIDs completed deprescribing tool questionnaire. To develop the questionnaire, a Medline literature search was performed. The panellists were asked to indicate for every medication class a possible need for stepwise withdrawal and strategy for withdrawal. They were asked in which situations withdrawal should be performed. Furthermore, panellists were requested to indicate those symptoms patients should be monitored for after deprescribing and a possible need for follow-ups. Results: Practical deprescribing guidance was developed for STOPPFall medication classes. For each medication class, a decision tree algorithm was developed including steps from medication review to symptom monitoring after medication withdrawal. Conclusion: STOPPFall was combined with a practical deprescribing tool designed to optimize medication review. This practical guide can help overcome current reluctance towards deprescribing in clinical practice by providing an up-to-date and straightforward source of expert knowledge

    Physical activity and exercise in dementia : an umbrella review of intervention and observational studies

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    Background: Dementia is a common condition in older people. Among the potential risk factors, increasing attention has been focused on sedentary behaviour. However, synthesizing literature exploring whether physical activity/exercise can affect health outcomes in people with dementia or with mild cognitive impairment (MCI) is still limited. Therefore, the aim of this umbrella review, promoted by the European Geriatric Medicine Society (EuGMS), is to understand the importance of physical activity/exercise for improving cognitive and non-cognitive outcomes in people with dementia/MCI. Methods: Umbrella review of systematic reviews (SR) (with or without meta-analyses) of randomized controlled trials (RCTs) and observational (prospective and case-control in people with MCI) studies based on a systematic literature search in several databases. The certainty of evidence of statistically significant outcomes attributable to physical activity/exercise interventions was evaluated using Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results: Among 1,160 articles initially evaluated, 27 systematic reviews (4 without meta-analysis) for a total of 28,205 participants with dementia/MCI were included. No observational study on physical activity/exercise in MCI for preventing dementia was included. In SRs with MAs, physical activity/exercise was effective in improving global cognition in Alzheimer’s disease and in all types of dementia (very low/low certainty of evidence). Moreover, physical activity/ exercise significantly improved global cognition, attention, executive function, and memory in MCI, with a certainty of evidence varying from low to moderate. Finally, physical activity/exercise improved non-cognitive outcomes in people with dementia including falls and neuropsychiatric symptoms. SRs, without meta-analysis, corroborated these results. Conclusions: Supported by very low to moderate certainty of evidence, physical activity/exercise has a positive effect on several cognitive and non-cognitive outcomes in people with dementia and MCI, but RCTs, with low risk of bias/confounding, are still needed to confirm these findings
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